INDUSTRY
Biotechnology Industry Stocks
The Biotechnology industry covers 555 US-listed companies on StockSifting — NYSE and NASDAQ stocks operating within the Healthcare sector of the American equity market. Companies in the Biotechnology space compete on recurring themes including Treatment, Clinical, Phase, Disease, Trial, which drive revenue growth, margin expansion, and long-term capital allocation decisions across the group. Representative names such as Vertex Pharmaceuticals Incorporated, Regeneron Pharmaceuticals, Inc., Moderna, Inc., and Revolution Medicines, Inc. show how businesses in this industry pursue differentiated strategies — through proprietary technology, distribution scale, pricing power, brand strength, or regulatory moats — to sustain returns above the cost of capital. For US investors, an industry-level screener is one of the most efficient ways to compare true peers: companies that face the same end-market demand, regulatory framework, raw material costs, and macroeconomic sensitivities, making valuation comparisons far more meaningful than cross-sector analysis. Key metrics to compare across Biotechnology industry stocks include P/E ratio for earnings valuation, ROCE for capital efficiency, ROE for equity profitability, Dividend Yield for income generation, Market Capitalisation for size and liquidity context, and the 52-week trading range for price momentum signals. Use the sortable table below to rank all 555 Biotechnology companies by any fundamental metric and identify which US-listed stocks in this industry offer the most attractive combination of quality, value, and income for your investment portfolio.
How to Analyse Biotechnology Industry Stocks
The Biotechnology industry page on StockSifting is built for US investors who want true peer comparison — businesses facing the same end-market dynamics, regulatory environment, and competitive pressures. Start by sorting the table by ROCE to identify the most capital-efficient operators in the group, then cross-reference with P/E to find high-quality companies available at reasonable valuations. Check Dividend Yield for income-oriented screening and the 52-week High/Low range for price momentum context. Click any company name to open its full profile — including quarterly financials, analyst data, and key ratios — to complete your due diligence before making any investment decision. All data is sourced from NYSE and NASDAQ filings and refreshed daily after US market close.
Key Metrics Explained for Biotechnology Industry Stocks
Every metric in the table below has a specific analytical purpose when comparing Biotechnology industry companies. Understanding what each ratio measures — and what a strong or weak reading looks like within this industry — is essential for making informed investment decisions.
- P/E Ratio (Price-to-Earnings)
- Measures how much investors pay for each dollar of trailing twelve-month earnings. A lower P/E relative to Biotechnology industry peers suggests a cheaper valuation; a higher P/E may reflect premium growth expectations or temporary earnings compression. Always compare P/E within the same industry — cross-sector P/E comparisons are misleading because capital intensity, growth rates, and margin profiles differ structurally.
- Market Capitalisation
- Total market value of a company's outstanding shares (price × shares outstanding). Within the Biotechnology industry, market cap indicates size, liquidity, and index eligibility. Large-cap companies (above $10B) typically offer more analyst coverage and tighter bid-ask spreads; small-caps may offer higher growth potential with commensurately higher risk and lower trading liquidity.
- ROCE — Return on Capital Employed
- Operating profit divided by total capital employed (equity + debt). ROCE is one of the most revealing profitability metrics for Biotechnology industry comparison: it shows which companies generate the most operating profit per dollar of total capital invested. ROCE consistently above 15% signals a strong competitive position; above 25% signals an exceptional business with durable advantages. Companies with high ROCE can self-fund growth and generate superior long-term shareholder returns without requiring continuous equity dilution or heavy borrowing.
- ROE — Return on Equity
- Net income divided by shareholders' equity. ROE measures how efficiently management generates profit from the equity shareholders have invested. In the Biotechnology industry, ROE above 15% is generally considered strong; below 8% raises questions about capital allocation efficiency. Note: high ROE driven by excessive leverage (high D/E ratio) is a warning sign rather than a quality indicator — always check debt levels alongside ROE.
- Dividend Yield
- Annual dividends per share as a percentage of the current share price. For income-oriented US investors, dividend yield is a key criterion — particularly in Biotechnology industry companies with stable, recurring cash flows. A yield significantly above the industry median may indicate an attractive income opportunity or, alternatively, a price decline that warrants further investigation into dividend sustainability. Always verify payout ratio and free cash flow coverage before relying on a high yield as an investment signal.
- 52-Week High / 52-Week Low
- The highest and lowest traded prices over the past 52 weeks. The 52-week range provides immediate context on price momentum and volatility within the Biotechnology industry: stocks trading near their 52-week high may reflect strong business momentum or elevated valuation; stocks near their 52-week low may represent contrarian opportunities or reflect deteriorating fundamentals. Always cross-reference with fundamental metrics rather than relying on price range alone.
Data Sources & Methodology
All financial data displayed on this Biotechnology industry page is sourced from NYSE and NASDAQ company filings, processed through StockSifting's daily data pipeline, and refreshed after each US market close. Fundamental metrics — earnings per share, book value, debt, and revenue — are updated as companies file quarterly reports (10-Q) and annual reports (10-K) with the SEC. Price data reflects the most recent closing price. StockSifting does not provide financial advice. All screening tools are for research and informational purposes only. Conduct your own due diligence before making any investment decision.
Biotechnology Industry Stocks — Frequently Asked Questions
Common questions US investors ask about the Biotechnology industry, answered with data from StockSifting's live screener.
What industry is Biotechnology on the US stock market?
Biotechnology is a recognised industry classification on the US equity market. StockSifting currently tracks 555 NYSE- and NASDAQ-listed companies in the Biotechnology industry, ranging from large-cap S&P 500 constituents to smaller-cap names. The Biotechnology industry page consolidates all these companies into a single sortable view, with live P/E ratio, market cap, ROCE, ROE, dividend yield, and 52-week price range data refreshed daily after US market close.
How many US stocks are in the Biotechnology industry?
StockSifting tracks 555 US-listed companies in the Biotechnology industry across NYSE and NASDAQ. Use the sortable table above to compare them by valuation, profitability, dividend yield, and trading range. Click any company name to open its full profile page with quarterly financials, key ratios, and historical data.
What metrics matter most for Biotechnology industry analysis?
For the Biotechnology industry, the most informative metrics to compare across peers are:
- ROCE — identifies companies with durable competitive advantages generating high returns on invested capital.
- P/E Ratio — measures relative valuation; low P/E within the industry may signal undervaluation.
- ROE — reveals how efficiently management deploys shareholder equity to generate profit.
- Dividend Yield — key for income-oriented US investors screening for reliable cash distributions.
- Market Cap — size and liquidity context; large-caps offer stability, small-caps offer growth potential.
- 52-Week Range — price momentum and volatility signal at a glance.
Comparing these metrics within the Biotechnology industry is more meaningful than cross-sector comparisons, because all companies face similar structural dynamics, cost bases, and regulatory environments.
How do I find the best Biotechnology industry stocks?
There is no single definition of "best" — it depends on your investment objective:
- Quality investors: Sort by ROCE descending to identify the most capital-efficient operators. Look for ROCE above 15% sustained over multiple years, combined with low D/E.
- Value investors: Sort by P/E ascending to find the cheapest earnings. Cross-reference with ROCE to avoid cheap junk — look for low P/E AND high ROCE simultaneously.
- Income investors: Sort by Dividend Yield descending. Verify sustainability by checking payout ratio and free cash flow in individual company profiles.
- Growth investors: Filter by market cap for smaller-cap names with high ROE, indicating efficient growth reinvestment.
Always click through to individual company pages for full due diligence. Nothing on this page constitutes financial advice. Past performance does not guarantee future results.
How often is the Biotechnology industry data updated?
StockSifting refreshes all Biotechnology industry data — price, P/E, market cap, ROCE, ROE, dividend yield, and 52-week range — daily after US market close. Fundamental data (earnings, book value, debt ratios) updates as companies file quarterly 10-Q and annual 10-K reports with the SEC. This means the screener reflects the most current publicly available information for every NYSE- and NASDAQ-listed company in the Biotechnology industry.
555 Companies in the Biotechnology Industry
Compare US-listed Biotechnology industry stocks by price, P/E ratio, market cap, dividend yield, ROCE, ROE, and 52-week high-low range. Click any column header to sort. Click any company name for the full profile.
| #↑ | Company↕ | Price↕ | P/E↕ | Mkt Cap↕ | Div Yield↕ | ROCE↕ | ROE↕ | 52W High↕ | 52W Low↕ |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals Incorporated | $451.63 | 26.79 | $114.63 B | — | — | 0.24% | $507.92 | $362.5 |
| 2 | Regeneron Pharmaceuticals, Inc. | $805.02 | 19.23 | $83.26 B | 0.45% | 10.23% | 13.81% | $859.34 | $572.75 |
| 3 | Moderna, Inc. | $200.1 | — | $79.56 B | — | -29.7% | -39.2% | $254.48 | $22.28 |
| 4 | Revolution Medicines, Inc. | $186.99 | — | $40.33 B | — | -57.28% | -54.06% | $224.31 | $52.48 |
| 5 | Royalty Pharma plc | $63.86 | 44.99 | $36.67 B | 2.96% | 8.21% | 12.25% | $64.38 | $35.91 |
| 6 | Roivant Sciences Ltd. | $36.49 | — | $35.24 B | — | -21.06% | -6.12% | $42.5 | $17.64 |
| 7 | Alnylam Pharmaceuticals, Inc. | $224.03 | 36.94 | $29.85 B | — | 14.33% | 93.61% | $485.36 | $197.81 |
| 8 | Incyte Corporation | $115.71 | 14.59 | $23.53 B | — | 24.67% | 29.6% | $132.6 | $84.02 |
| 9 | Insmed Incorporated | $93.39 | — | $20.56 B | — | -55.4% | -111.26% | $212.75 | $90.39 |
| 10 | Exelixis, Inc. | $64.53 | 18.62 | $16.02 B | — | 36.6% | 42.49% | $65.5 | $35.44 |
| 11 | Ascendis Pharma A/S | $230.83 | 26.29 | $15.14 B | — | — | 3.33% | $250.74 | $160.86 |
| 12 | Halozyme Therapeutics, Inc. | $125.63 | 34.07 | $14.09 B | — | 34.18% | 180.63% | $125.43 | $61.23 |
| 13 | Jazz Pharmaceuticals plc | $214 | 14.75 | $13.88 B | — | 5.5% | 21.37% | $266.38 | $128.8 |
| 14 | BridgeBio Pharma, Inc. | $68.56 | — | $13.4 B | — | -77.47% | -206.74% | $93.42 | $52.75 |
| 15 | Summit Therapeutics Inc. | $15.47 | — | $12.37 B | — | -161.37% | -168.93% | $29.23 | $12.07 |
| 16 | Bio-Techne Corporation | $72.55 | 62.6 | $11.38 B | 0.5% | 10.19% | 8.9% | $72.69 | $43.2 |
| 17 | Corcept Therapeutics Incorporated | $85.86 | 203.85 | $11.25 B | — | 6.68% | 8.41% | $126.38 | $28.66 |
| 18 | BioMarin Pharmaceutical Inc. | $55.95 | 147.72 | $10.78 B | — | 5.99% | 1.18% | $70.98 | $49.26 |
| 19 | Apogee Therapeutics, Inc. | $0 | — | $10.22 B | — | -31.41% | -29.88% | $135.09 | $51.8 |
| 20 | Madrigal Pharmaceuticals, Inc. | $434.24 | — | $10.03 B | — | -31.61% | -56.65% | $615 | $393.61 |
| 21 | Nuvalent, Inc. | $0 | — | $9.79 B | — | -31.35% | -42.78% | $123.99 | $87.3 |
| 22 | Vaxcyte, Inc. | $60.43 | — | $9.58 B | — | -33.02% | -37.57% | $90.75 | $39.87 |
| 23 | Krystal Biotech, Inc. | $311.5 | 38.32 | $9.25 B | — | 13.1% | 19.34% | $382.54 | $183.03 |
| 24 | Kymera Therapeutics, Inc. | $110.76 | — | $9.21 B | — | -20.82% | -21.5% | $130.05 | $55.26 |
| 25 | Crinetics Pharmaceuticals, Inc. | $0 | — | $9.01 B | — | -49.63% | -44.22% | $85.01 | $32.3 |
| 26 | Caris Life Sciences, Inc. | $32 | 85.23 | $8.96 B | — | 4.52% | 18.77% | $33.13 | $14.19 |
| 27 | Protagonist Therapeutics, Inc. | $138.43 | 107.71 | $8.93 B | — | -25.39% | 12.03% | $160.81 | $73.08 |
| 28 | ImmunityBio, Inc. | $8.22 | — | $8.75 B | — | -58.17% | -193.29% | $12.43 | $1.95 |
| 29 | Cytokinetics, Incorporated | $61.23 | — | $8.54 B | — | -50.1% | -131.19% | $88.31 | $54.3 |
| 30 | Spyre Therapeutics, Inc. | $90.33 | — | $8.39 B | — | -30.53% | -24.32% | $110.17 | $21.14 |
| 31 | Arrowhead Pharmaceuticals, Inc. | $58.02 | 53.97 | $8.19 B | — | 8.27% | -60.54% | $95.49 | $36.73 |
| 32 | TG Therapeutics, Inc. | $54.17 | 18.43 | $8.14 B | — | 13.56% | 72.3% | $59.3 | $26.76 |
| 33 | Axsome Therapeutics, Inc. | $145.04 | — | $7.65 B | — | -54.42% | -255.6% | $260.19 | $123.5 |
| 34 | Ionis Pharmaceuticals, Inc. | $42.93 | — | $7.11 B | — | -13.92% | -110.92% | $86.74 | $42.08 |
| 35 | Praxis Precision Medicines, Inc. | $252.96 | — | $7.06 B | — | -37.15% | -43.02% | $392.7 | $154.45 |
| 36 | Arcellx Inc | $0 | — | $6.73 B | — | -50.64% | -55.46% | $115.13 | $60.35 |
| 37 | Iovance Biotherapeutics, Inc. | $14.09 | — | $6.37 B | — | -51.39% | -40.51% | $15.37 | $1.76 |
| 38 | Rhythm Pharmaceuticals, Inc. | $89.27 | — | $6.19 B | — | -51.31% | -80.48% | $122.2 | $74.5 |
| 39 | Ligand Pharmaceuticals Incorporated | $303.53 | 31.08 | $6.13 B | — | 3.1% | 20.06% | $326.63 | $175.89 |
| 40 | Terns Pharmaceuticals, Inc. | $0 | — | $6.12 B | — | -10.92% | -20.02% | $53.19 | $6.99 |
| 41 | Immunovant, Inc. | $28.41 | — | $5.89 B | — | -61.93% | -69.59% | $45.42 | $18.51 |
| 42 | Veradermics, Incorporated | $138.78 | — | $5.79 B | — | -49.88% | -35.49% | $139.12 | $32 |
| 43 | CG Oncology, Inc. | $61.71 | — | $5.54 B | — | -25.08% | -25.2% | $80.97 | $35.8 |
| 44 | Kodiak Sciences Inc. | $87.63 | — | $5.51 B | — | -76.6% | -273.23% | $104 | $15.83 |
| 45 | Cogent Biosciences, Inc. | $31.21 | — | $5.42 B | — | -38.16% | -72.57% | $43.73 | $13.78 |
| 46 | Oruka Therapeutics, Inc. | $80.15 | — | $5.33 B | — | -25.79% | -20.76% | $115.52 | $25.11 |
| 47 | PTC Therapeutics, Inc. | $60.59 | 792.55 | $5.26 B | — | 44.37% | -351.91% | $90.87 | $58.8 |
| 48 | Mirum Pharmaceuticals, Inc. | $80.39 | — | $5.25 B | — | -3.47% | -289.33% | $130 | $63.23 |
| 49 | Apellis Pharmaceuticals, Inc. | $0 | 39.41 | $5.25 B | — | 7.37% | 39.71% | $41.14 | $16.83 |
| 50 | Scholar Rock Holding Corporation | $41.49 | — | $5.09 B | — | -110.26% | -159.12% | $61.76 | $27.07 |
| 51 | Erasca, Inc. | $14.39 | — | $5.03 B | — | -35.74% | -80.43% | $24.28 | $2.1 |
| 52 | Definium Therapeutics, Inc. | $35.67 | — | $4.83 B | — | -44.54% | -85.23% | $49.7 | $10.46 |
| 53 | CRISPR Therapeutics AG | $49.39 | — | $4.76 B | — | -31.41% | -24.39% | $70.73 | $44.12 |
| 54 | Travere Therapeutics, Inc. | $50.08 | — | $4.72 B | — | -14.11% | -55.79% | $68.73 | $22.59 |
| 55 | Amicus Therapeutics Inc | $0 | — | $4.55 B | — | 4.84% | -12.02% | $14.5 | $8.09 |
| 56 | Dianthus Therapeutics, Inc. | $76.78 | — | $4.31 B | — | -35.57% | -22.53% | $117.88 | $32.22 |
| 57 | Edgewise Therapeutics, Inc. | $39.31 | — | $4.27 B | — | -36.44% | -39.01% | $48.51 | $14.68 |
| 58 | Relay Therapeutics, Inc. | $18.18 | — | $3.95 B | — | -50.82% | -42.27% | $21.27 | $5.95 |
| 59 | Arcutis Biotherapeutics, Inc. | $31.2 | 138.17 | $3.94 B | — | -4.03% | 15.05% | $33.3 | $19.3 |
| 60 | Tango Therapeutics, Inc. | $23.34 | — | $3.94 B | — | -29.52% | -25.74% | $34.39 | $6.69 |
| 61 | Catalyst Pharmaceuticals, Inc. | $0 | 17.42 | $3.85 B | — | 26.94% | 23.65% | $32.56 | $20.32 |
| 62 | AbCellera Biologics Inc. | $11.82 | — | $3.83 B | — | -15.72% | -17.49% | $15.02 | $2.75 |
| 63 | Xenon Pharmaceuticals Inc. | $35.34 | — | $3.54 B | — | -63.09% | -43.98% | $72.66 | $33.38 |
| 64 | Viking Therapeutics, Inc. | $30.38 | — | $3.53 B | — | — | -0.7% | $43.15 | $22.96 |
| 65 | ACADIA Pharmaceuticals Inc. | $19.73 | 9.02 | $3.43 B | — | 8.14% | 32.39% | $30.96 | $18.39 |
| 66 | IDEAYA Biosciences, Inc. | $34.71 | — | $3.37 B | — | -15.17% | -16.47% | $42.68 | $26.81 |
| 67 | Tarsus Pharmaceuticals, Inc. | $68.2 | — | $3.36 B | — | -16.64% | -13.53% | $91.53 | $53.89 |
| 68 | Celcuity Inc. | $65.25 | — | $3.22 B | — | -40.76% | -244.61% | $151.02 | $53.54 |
| 69 | Enliven Therapeutics, Inc. | $41.52 | — | $3.03 B | — | -26.04% | -18.55% | $62.32 | $14.79 |
| 70 | Denali Therapeutics Inc. | $18.41 | — | $2.93 B | — | -53.07% | -55.27% | $27.3 | $13.75 |
| 71 | Dyne Therapeutics, Inc. | $15.62 | — | $2.92 B | — | -41.2% | -64.3% | $27.3 | $14 |
| 72 | NewAmsterdam Pharma Company N.V. | $19.71 | — | $2.89 B | — | -33.02% | -38.33% | $42.2 | $19.58 |
| 73 | Disc Medicine, Inc. | $74.51 | — | $2.86 B | — | -30.64% | -37.17% | $99.5 | $40 |
| 74 | Nurix Therapeutics, Inc. | $25.34 | 9.4 | $2.77 B | — | -47.48% | 49.34% | $28.23 | $10.28 |
| 75 | Soleno Therapeutics, Inc. | $0 | 28.77 | $2.76 B | — | 2.98% | 22.86% | $72.8 | $29.43 |
| 76 | AtaiBeckley Inc. | $7.35 | — | $2.73 B | — | -76% | -353.23% | $7.45 | $3.27 |
| 77 | Viridian Therapeutics, Inc. | $22.37 | — | $2.58 B | — | -43.85% | -61.35% | $34.29 | $13.18 |
| 78 | Kailera Therapeutics, Inc. | $19.9 | — | $2.58 B | — | — | -0.37% | $28.23 | $18.5 |
| 79 | Beam Therapeutics Inc. | $24.05 | — | $2.48 B | — | -27.72% | -7.7% | $38.26 | $20.23 |
| 80 | Pharvaris N.V. | $31.41 | — | $2.46 B | — | -54.28% | -61.01% | $43.25 | $21.02 |
| 81 | ADMA Biologics, Inc. | $10.68 | 14.52 | $2.45 B | — | 34.51% | 39.59% | $20.46 | $7.21 |
| 82 | MBX Biosciences, Inc. | $48.5 | — | $2.43 B | — | -26.53% | -26.01% | $72.64 | $14.61 |
| 83 | Arcus Biosciences, Inc. | $18.54 | — | $2.38 B | — | -42.51% | -89.54% | $31.73 | $16.41 |
| 84 | SELLAS Life Sciences Group, Inc. | $11.54 | — | $2.31 B | — | -39.64% | -35.91% | $15.88 | $1.39 |
| 85 | Celldex Therapeutics, Inc. | $29.25 | — | $2.29 B | — | -54.02% | -52.35% | $45.14 | $22.1 |
| 86 | Fortrea Holdings Inc. | $23.63 | — | $2.27 B | — | -1.7% | -15.53% | $24.84 | $8.55 |
| 87 | Aurinia Pharmaceuticals Inc. | $16.86 | 7.15 | $2.25 B | — | 16.2% | 59% | $19.25 | $11.48 |
| 88 | Day One Biopharmaceuticals Inc | $0 | — | $2.22 B | — | -28.56% | -23.43% | $21.53 | $6.9 |
| 89 | Agios Pharmaceuticals, Inc. | $37 | — | $2.22 B | — | -38.86% | -35.67% | $46 | $22.24 |
| 90 | Biohaven Ltd. | $13.88 | — | $2.22 B | — | -222.16% | -639.95% | $18.57 | $7.48 |
| 91 | Precigen, Inc. | $6.19 | — | $2.21 B | — | -90.19% | -498.32% | $8.98 | $3.04 |
| 92 | Recursion Pharmaceuticals, Inc. | $3.7 | — | $2.21 B | — | -48.86% | -50.41% | $6.5 | $2.77 |
| 93 | Vera Therapeutics, Inc. | $27.99 | — | $2.2 B | — | -46.31% | -84.13% | $56.05 | $23.05 |
| 94 | Immunome, Inc. | $17.99 | — | $2.12 B | — | -35.12% | -50.56% | $30.06 | $14.64 |
| 95 | Harmony Biosciences Holdings, Inc. | $36.13 | 11.61 | $2.1 B | — | 20.45% | 20.06% | $43.49 | $25.9 |
| 96 | Vericel Corporation | $40.1 | 93.26 | $2.05 B | — | — | 0.07% | $43.57 | $28.95 |
| 97 | Zymeworks Inc. | $28.22 | — | $1.99 B | — | -30.42% | -72.07% | $31.34 | $16 |
| 98 | Septerna, Inc. | $40.41 | — | $1.91 B | — | -15.87% | -6.31% | $51.1 | $17.55 |
| 99 | Maravai LifeSciences Holdings, Inc. | $7.32 | — | $1.9 B | — | -17.71% | -35.42% | $9.42 | $2.54 |
| 100 | Mineralys Therapeutics, Inc. | $20.55 | — | $1.9 B | — | -26.38% | -57.97% | $47.65 | $20.12 |
| 101 | Xencor, Inc. | $25.18 | — | $1.87 B | — | -22.77% | -28.66% | $30.61 | $10.38 |
| 102 | Sarepta Therapeutics, Inc. | $17.73 | 27.89 | $1.85 B | — | -29.18% | -9.96% | $24.68 | $14.68 |
| 103 | Zenas BioPharma, Inc. | $26.87 | — | $1.85 B | — | -65.85% | -189.68% | $44.6 | $13.5 |
| 104 | Palvella Therapeutics, Inc. | $125.1 | — | $1.8 B | — | -80.06% | -47.84% | $161.38 | $68.96 |
| 105 | uniQure N.V. | $22.43 | — | $1.8 B | — | -24.65% | -111.96% | $71.5 | $8.73 |
| 106 | Trevi Therapeutics, Inc. | $12.61 | — | $1.79 B | — | -26.85% | -23.59% | $20.22 | $9.82 |
| 107 | Vir Biotechnology, Inc. | $10.57 | — | $1.78 B | — | -52.69% | -14.86% | $12 | $4.82 |
| 108 | Maze Therapeutics, Inc. | $31.01 | — | $1.77 B | — | -38.15% | -34.94% | $53.65 | $21.95 |
| 109 | UroGen Pharma Ltd. | $34.49 | — | $1.69 B | — | -81.06% | -204.47% | $50.81 | $16.5 |
| 110 | Nuvation Bio Inc. | $4.57 | — | $1.65 B | — | -41.57% | -49.73% | $9.75 | $3.92 |
| 111 | Generate Biomedicines, Inc. | $12.41 | — | $1.64 B | — | -94.79% | -103.72% | $22.67 | $11 |
| 112 | Forte Biosciences, Inc. | $0 | — | $1.63 B | — | -113.91% | -94.82% | $77.2 | $10.3 |
| 113 | Silence Therapeutics plc | $19.67 | — | $1.63 B | — | -76.17% | -103.26% | $6.38 | $1.06 |
| 114 | Stoke Therapeutics, Inc. | $25.04 | — | $1.61 B | — | -5.71% | -59.36% | $40.22 | $20.32 |
| 115 | Novavax, Inc. | $9.7 | 3.52 | $1.61 B | — | 76.84% | 283.08% | $13.38 | $6.2 |
| 116 | Ascentage Pharma Group Internat | $15.44 | — | $1.59 B | — | -25.48% | -156.17% | $70.05 | $27.12 |
| 117 | Absci Corporation | $9.18 | — | $1.58 B | — | -64.8% | -59.21% | $12.05 | $2.24 |
| 118 | Ultragenyx Pharmaceutical Inc. | $15.65 | — | $1.57 B | — | -46.6% | -414.17% | $39.89 | $12.73 |
| 119 | Intellia Therapeutics, Inc. | $11.21 | — | $1.55 B | — | -59.74% | -57.79% | $26.9 | $7.95 |
| 120 | Cyclerion Therapeutics, Inc. | $31.41 | — | $1.55 B | — | -40.99% | -87.96% | $59.36 | $7.19 |
| 121 | Innoviva, Inc. | $20.66 | 4.19 | $1.5 B | — | 10.33% | 30.03% | $25.15 | $17.22 |
| 122 | Ocular Therapeutix, Inc. | $6.5 | — | $1.45 B | — | -35.66% | -59.87% | $16.44 | $6 |
| 123 | AnaptysBio, Inc. | $48.73 | 7.35 | $1.44 B | — | 14.7% | 894.97% | $72.36 | $20.18 |
| 124 | KalVista Pharmaceuticals, Inc. | $0 | — | $1.44 B | — | -89% | -237.53% | $27 | $10.41 |
| 125 | Inhibrx Biosciences, Inc. | $93.38 | — | $1.43 B | — | -119.83% | -269.56% | $155.29 | $28.16 |
| 126 | Tyra Biosciences, Inc. | $20.45 | — | $1.41 B | — | -50.19% | -46.39% | $40.65 | $13.35 |
| 127 | Avalyn Pharma Inc. | $31.45 | — | $1.39 B | — | — | -0.68% | $32.23 | $24.15 |
| 128 | Hemab Therapeutics Holdings, Inc. | $29.24 | — | $1.37 B | — | — | -0.47% | $36.61 | $23 |
| 129 | ORIC Pharmaceuticals, Inc. | $13.17 | — | $1.36 B | — | -36.81% | -35.35% | $14.68 | $7.23 |
| 130 | Damora Therapeutics, Inc. | $21.09 | — | $1.3 B | — | -87.69% | -83.06% | $34.89 | $16.5 |
| 131 | Taysha Gene Therapies, Inc. | $3.96 | — | $1.29 B | — | -34.88% | -56.19% | $7.3 | $3.46 |
| 132 | Rapport Therapeutics, Inc. | $25.93 | — | $1.27 B | — | -25.36% | -29.02% | $52.93 | $23.75 |
| 133 | LB Pharmaceuticals Inc | $38.73 | — | $1.27 B | — | -9.95% | -25.91% | $50.16 | $14.32 |
| 134 | Nektar Therapeutics | $37.22 | — | $1.26 B | — | -57.64% | -37.54% | $109 | $33.4 |
| 135 | GH Research PLC | $18.07 | — | $1.24 B | — | -21.68% | -20.86% | $31.44 | $12.04 |
| 136 | Immatics N.V. | $7.31 | — | $1.22 B | — | -35.05% | -47.04% | $12.41 | $6.65 |
| 137 | Alpha Tau Medical Ltd. | $13.16 | — | $1.22 B | — | -44.45% | -73.23% | $15.79 | $3.43 |
| 138 | Omeros Corporation | $16.57 | 9.64 | $1.2 B | — | -49.6% | 107.5% | $21.24 | $6.24 |
| 139 | Syndax Pharmaceuticals, Inc. | $13.4 | — | $1.19 B | — | -66.67% | -372.94% | $25.59 | $12.79 |
| 140 | Verastem, Inc. | $10.04 | — | $1.19 B | — | -97.68% | -165.4% | $10.82 | $3.43 |
| 141 | Bicara Therapeutics Inc. | $17.07 | — | $1.17 B | — | -38.7% | -41.49% | $30.99 | $13.7 |
| 142 | Replimune Group, Inc. | $11.46 | — | $1.09 B | — | -53.14% | -159.32% | $16.33 | $1.5 |
| 143 | Vor Biopharma Inc. | $18.26 | 1.72 | $1.08 B | — | -84.67% | -142.13% | $28.66 | $6.5 |
| 144 | Janux Therapeutics, Inc. | $16.66 | — | $1.02 B | — | -16.15% | -10.79% | $35.34 | $12.12 |
| 145 | MoonLake Immunotherapeutics | $11.85 | — | $1.01 B | — | -64.61% | -82.68% | $23.29 | $8.9 |
| 146 | MannKind Corporation | $3.19 | 144.86 | $1 B | — | 7.49% | -297.71% | $6.51 | $2.23 |
| 147 | Seaport Therapeutics, Inc. | $18.17 | — | $972.65 M | — | — | -0.28% | $23 | $14.85 |
| 148 | ArriVent BioPharma, Inc. | $21 | — | $946.71 M | — | -57.79% | -50.26% | $35.83 | $11.36 |
| 149 | SpyGlass Pharma, Inc. | $28.48 | — | $943.9 M | — | -38.64% | -56.78% | $32.44 | $17.06 |
| 150 | Aktis Oncology, Inc. | $15.73 | — | $932.18 M | — | -31.96% | -30.8% | $34.19 | $14.72 |
| 151 | Jade Biosciences, Inc. | $14.59 | — | $927.89 M | 0% | -34.07% | -49.11% | $28 | $8.36 |
| 152 | Monte Rosa Therapeutics, Inc. | $10.84 | — | $924.8 M | — | -14.1% | -43.31% | $25.77 | $8.94 |
| 153 | Cullinan Therapeutics, Inc. | $14.37 | — | $924.78 M | — | -58.85% | -52.89% | $23.19 | $6.73 |
| 154 | Alumis Inc. | $6.78 | — | $910.44 M | — | -134.01% | -102.97% | $31.35 | $4.37 |
| 155 | Rigel Pharmaceuticals, Inc. | $48.13 | 2.81 | $902.98 M | — | 30.28% | 96.49% | $52.24 | $24.95 |
| 156 | Odyssey Therapeutics, Inc. | $19.07 | — | $899.61 M | — | — | -0.86% | $20.3 | $15.35 |
| 157 | Theravance Biopharma, Inc. | $17.03 | 16.43 | $884.18 M | — | -0.81% | 19.4% | $21.03 | $13.08 |
| 158 | MeiraGTx Holdings plc | $9.21 | 11.11 | $877.83 M | — | -86.95% | 74.56% | $15.35 | $6.62 |
| 159 | Corvus Pharmaceuticals, Inc. | $10.53 | — | $873.18 M | — | -69.6% | -36.15% | $26.95 | $6.39 |
| 160 | Alto Neuroscience, Inc. | $21.97 | — | $871.17 M | — | -38.28% | -46.46% | $37.48 | $9.73 |
| 161 | Savara Inc. | $4.22 | — | $857.8 M | — | -52.68% | -90.28% | $7 | $3.86 |
| 162 | Kura Oncology, Inc. | $9.61 | — | $851.8 M | — | -48.86% | -207.18% | $13.9 | $7.36 |
| 163 | Arbutus Biopharma Corporation | $4.2 | 5.45 | $834.03 M | — | -30.53% | 90.98% | $5.45 | $3.5 |
| 164 | Ardelyx, Inc. | $3.08 | — | $797.4 M | — | -9.92% | -36% | $8.4 | $3.05 |
| 165 | Annexon, Inc. | $3.75 | — | $710.92 M | — | -92.11% | -106.15% | $7.18 | $2.54 |
| 166 | XOMA Royalty Corporation | $0 | 21 | $710.16 M | 0.78% | 4.79% | 32.41% | $45.22 | $22.29 |
| 167 | Geron Corporation | $1.12 | — | $706.72 M | — | -11.23% | -29.32% | $2.01 | $1.04 |
| 168 | Eupraxia Pharmaceuticals Inc. | $6.87 | — | $701.91 M | — | -47.73% | -45.53% | $13.08 | $7.35 |
| 169 | Sana Biotechnology, Inc. | $2.33 | — | $697.51 M | — | -60.83% | -134.49% | $5.9 | $2.22 |
| 170 | OmniAb, Inc. | $4.66 | — | $694.97 M | — | -24.23% | -16.59% | $5.43 | $1.3 |
| 171 | Prime Medicine, Inc. | $3.67 | — | $676.54 M | — | -68.25% | -188.27% | $5.62 | $2.67 |
| 172 | Immix Biopharma, Inc. | $8.15 | — | $675.66 M | — | -31.62% | -38.44% | $15.1 | $2.85 |
| 173 | Sagimet Biosciences Inc. | $9.58 | — | $673.87 M | — | -51.08% | -31.96% | $11.45 | $4.5 |
| 174 | Ginkgo Bioworks Holdings, Inc. | $9.99 | — | $672.73 M | — | -29.68% | -60.21% | $18.22 | $5.37 |
| 175 | Achieve Life Sciences, Inc. | $6.49 | — | $664.24 M | — | -167.79% | -193.49% | $8.64 | $2.62 |
| 176 | Nuvectis Pharma, Inc. | $20.05 | — | $654.51 M | — | -149.75% | -169.47% | $29.27 | $5.55 |
| 177 | Aura Biosciences, Inc. | $6.3 | — | $653.34 M | — | -74.67% | -73.18% | $9.54 | $4.73 |
| 178 | Design Therapeutics, Inc. | $10.24 | — | $640.84 M | — | -37.28% | -34.03% | $17.25 | $5.28 |
| 179 | Wave Life Sciences Ltd. | $3.18 | — | $639.89 M | — | -39.63% | -49.87% | $21.73 | $3.04 |
| 180 | Lexicon Pharmaceuticals, Inc. | $1.42 | — | $638.51 M | — | -29.8% | -40.4% | $2.68 | $1.1 |
| 181 | Solid Biosciences Inc. | $5.92 | — | $633.17 M | — | -90.02% | -72.28% | $11.45 | $3.79 |
| 182 | CorMedix Inc. | $7.85 | 3.37 | $631.35 M | — | 23.03% | 44.64% | $13.02 | $6.13 |
| 183 | Gyre Therapeutics, Inc. | $5.85 | 119.4 | $623.48 M | — | 7.77% | -15.84% | $9.14 | $5.44 |
| 184 | Candel Therapeutics, Inc. | $8.03 | — | $614.44 M | — | -41.46% | -89.38% | $14 | $4.35 |
| 185 | First Tracks Biotherapeutics, Inc. | $17.42 | — | $607.83 M | — | — | — | $26.8 | $14.72 |
| 186 | Oculis Holding AG | $7.9 | — | $605.35 M | — | -41% | -42.65% | $34.48 | $7.11 |
| 187 | 4D Molecular Therapeutics, Inc. | $10.8 | — | $596.64 M | — | -30.52% | -41.33% | $16.93 | $6.96 |
| 188 | Bright Minds Biosciences Inc. | $60.66 | — | $595.2 M | — | — | -0.15% | $123.75 | $23.18 |
| 189 | Zevra Therapeutics, Inc. | $9.81 | 10.11 | $588.86 M | — | -1.72% | 32.77% | $15.04 | $8.01 |
| 190 | Climb Bio, Inc. | $10.19 | — | $585.28 M | — | -42.23% | -31.79% | $18.33 | $1.64 |
| 191 | MiMedx Group, Inc. | $3.91 | 91.35 | $569.92 M | — | 22.95% | 2.61% | $7.97 | $3.03 |
| 192 | Puma Biotechnology, Inc. | $11.02 | 21.28 | $568.6 M | — | 27.62% | 20.85% | $11.38 | $4.58 |
| 193 | Olema Pharmaceuticals, Inc. | $6.41 | — | $560.86 M | — | -37.1% | -48.22% | $36.26 | $6.48 |
| 194 | Shattuck Labs, Inc. | $5.49 | — | $550.99 M | — | -61.34% | -43.57% | $8.33 | $1.72 |
| 195 | Aclaris Therapeutics, Inc. | $3.75 | — | $549.79 M | — | -53.3% | -61.65% | $6.6 | $2.1 |
| 196 | CytomX Therapeutics, Inc. | $2.32 | — | $514.24 M | — | -21.31% | -38.46% | $8.21 | $2.2 |
| 197 | Entera Bio Ltd. | $2.92 | — | $503.51 M | — | -83.6% | -147.19% | $4.2 | $0.91 |
| 198 | AgomAb Therapeutics NV | $9.05 | — | $502.41 M | — | -24.35% | -47.78% | $17.82 | $7.92 |
| 199 | Crescent Biopharma, Inc. | $12.82 | — | $488.07 M | — | -74.74% | -100.26% | $27.41 | $8.72 |
| 200 | Indaptus Therapeutics, Inc. | $3.16 | — | $485.32 M | — | -629.32% | -302.75% | $5.96 | $0.92 |
| 201 | Arvinas, Inc. | $7.3 | 51.04 | $474.7 M | — | -20.59% | 1.91% | $14.51 | $6.74 |
| 202 | DiaMedica Therapeutics Inc. | $8.72 | — | $470.5 M | — | -61.16% | -77.68% | $10.42 | $5.25 |
| 203 | Neurogene Inc. | $23.55 | — | $469.07 M | — | -37.96% | -25.27% | $43.66 | $15.93 |
| 204 | Phathom Pharmaceuticals, Inc. | $5.74 | — | $464.37 M | — | -125.87% | -232.78% | $18.31 | $6.52 |
| 205 | MapLight Therapeutics, Inc. | $7.97 | — | $458.5 M | — | -36.5% | -63.84% | $40.43 | $7.46 |
| 206 | Monopar Therapeutics Inc. | $67.47 | — | $451.99 M | — | — | -0.16% | $105 | $29.18 |
| 207 | REGENXBIO Inc. | $6.68 | — | $448.23 M | — | -48.13% | -220.07% | $16.19 | $5.46 |
| 208 | Eikon Therapeutics, Inc. | $7.26 | — | $446.32 M | — | -62.8% | -119.66% | $17.4 | $6.45 |
| 209 | Ovid Therapeutics Inc. | $2.16 | — | $431.61 M | — | -29.75% | -23.64% | $3.1 | $1.18 |
| 210 | Allogene Therapeutics, Inc. | $1.25 | — | $430.14 M | — | -53.97% | -35.31% | $4.46 | $1.04 |
| 211 | ProKidney Corp. | $1.41 | — | $426.27 M | — | -54.13% | -28.1% | $3.48 | $1.3 |
| 212 | Prothena Corporation plc | $8.2 | — | $423.53 M | — | -64.54% | -14.98% | $11.8 | $7.73 |
| 213 | Nautilus Biotechnology, Inc. | $3.24 | — | $412.31 M | — | -36.49% | -37.58% | $4.31 | $0.84 |
| 214 | Altimmune, Inc. | $2.12 | — | $411.09 M | — | -35.67% | -31.41% | $6.44 | $2.15 |
| 215 | Assembly Biosciences, Inc. | $19.84 | — | $401.71 M | — | -5.8% | -0.02% | $39.7 | $19.94 |
| 216 | ARS Pharmaceuticals, Inc. | $4.03 | — | $400.77 M | — | -62.2% | -256.67% | $13.15 | $3.81 |
| 217 | Tectonic Therapeutic, Inc. | $20.07 | — | $392.55 M | — | -33.43% | -35.26% | $39.53 | $15.52 |
| 218 | C4 Therapeutics, Inc. | $3.06 | — | $376.46 M | — | -32.05% | -45.45% | $5.17 | $1.69 |
| 219 | Zura Bio Limited | $3.36 | — | $374.59 M | — | -74.11% | -54.45% | $7.44 | $3.15 |
| 220 | Rezolute, Inc. | $3.85 | — | $372.89 M | — | -48.84% | -62.99% | $11.46 | $1.07 |
| 221 | Editas Medicine, Inc. | $2.4 | — | $364.75 M | — | -70.81% | -196.63% | $4.21 | $1.66 |
| 222 | Avalo Therapeutics, Inc. | $6.93 | — | $363.34 M | — | -70.45% | -58.03% | $24.27 | $11.21 |
| 223 | Conexeu Sciences Inc. | $13.28 | — | $355.35 M | — | — | — | $18.79 | $9.6 |
| 224 | Kyverna Therapeutics, Inc. | $5.39 | — | $354.36 M | — | -65.99% | -81.91% | $13.67 | $5.61 |
| 225 | Fennec Pharmaceuticals Inc. | $10.08 | — | $351.37 M | — | -10.57% | -6.78% | $13.25 | $5.65 |
| 226 | Relmada Therapeutics, Inc. | $3.27 | — | $348.28 M | — | -67.49% | -47.52% | $8 | $1.98 |
| 227 | Capricor Therapeutics, Inc. | $5.93 | — | $344.76 M | — | -33.78% | -56.6% | $40.37 | $2.96 |
| 228 | Galectin Therapeutics Inc. | $3.19 | — | $340.87 M | — | -174.62% | -258.62% | $7.13 | $2.02 |
| 229 | Enanta Pharmaceuticals, Inc. | $11.64 | — | $338.44 M | — | -36.76% | -61.84% | $17.15 | $10.2 |
| 230 | Orchestra BioMed Holdings, Inc. | $5.59 | — | $328.77 M | — | -52.8% | -125.78% | $6.5 | $3.46 |
| 231 | Atea Pharmaceuticals, Inc. | $4.04 | — | $324.03 M | — | -65.67% | -64.25% | $6.45 | $2.87 |
| 232 | X4 Pharmaceuticals, Inc. | $3.24 | — | $317.72 M | — | -32.82% | -63.05% | $4.83 | $2.43 |
| 233 | Contineum Therapeutics, Inc. | $8.31 | — | $315.83 M | — | -25.5% | -24.73% | $17.79 | $6.72 |
| 234 | Turn Therapeutics Inc. | $10.28 | — | $310.82 M | — | -134.02% | -281.64% | $16.45 | $2.57 |
| 235 | Benitec Biopharma Inc. | $8.65 | — | $301.79 M | — | -42.71% | -34.82% | $16.76 | $8 |
| 236 | Artiva Biotherapeutics, Inc. | $6.15 | — | $300.67 M | — | -76.21% | -60.22% | $14.53 | $2.96 |
| 237 | Surrozen, Inc. | $25.48 | — | $299.48 M | — | -47.4% | 58.23% | $37.83 | $11.39 |
| 238 | AC Immune SA | $2.42 | — | $297.92 M | — | -115.62% | -99.2% | $4 | $2.1 |
| 239 | Prelude Therapeutics Incorporated | $3.63 | — | $289.69 M | — | -118.39% | -75.35% | $6.83 | $1.17 |
| 240 | Opus Genetics, Inc. | $3.47 | — | $288.69 M | — | -90.9% | -316.35% | $7.07 | $1.7 |
| 241 | Arcturus Therapeutics Holdings Inc. | $9.84 | — | $281.67 M | — | -32.48% | -46.54% | $17.96 | $5.5 |
| 242 | Agenus Inc. | $6.33 | 3.06 | $281.36 M | — | 21.26% | 76.63% | $10.31 | $2.71 |
| 243 | Fulcrum Therapeutics, Inc. | $3.68 | — | $280.39 M | — | -24% | -22.54% | $15.74 | $2.83 |
| 244 | SAB Biotherapeutics, Inc. | $2.84 | 20.84 | $276.6 M | — | -30.19% | 15.17% | $5.15 | $2.44 |
| 245 | Alector, Inc. | $1.83 | — | $270.57 M | — | -69.73% | -295.17% | $2.76 | $1.09 |
| 246 | Century Therapeutics, Inc. | $1.46 | — | $264.37 M | — | -5.16% | -52.76% | $3.04 | $0.43 |
| 247 | InflaRx N.V. | $1.56 | — | $257.44 M | — | -114.26% | -37.43% | $2.95 | $0.8 |
| 248 | Q32 Bio Inc. | $8.65 | 8.61 | $256.76 M | — | 33.52% | 137.41% | $23.57 | $1.91 |
| 249 | Lineage Cell Therapeutics, Inc. | $1 | — | $254.17 M | — | -21.52% | -71.14% | $2.09 | $0.88 |
| 250 | Fate Therapeutics, Inc. | $2.11 | — | $250.42 M | — | -52.22% | -65.08% | $3.23 | $0.95 |
| 251 | Ocugen, Inc. | $0.74 | — | $249.89 M | — | -307.31% | -1306.71% | $2.73 | $0.78 |
| 252 | Abeona Therapeutics Inc. | $4.4 | 5.5 | $247.61 M | — | -47.08% | -41.69% | $7.65 | $4 |
| 253 | Rocket Pharmaceuticals, Inc. | $2.29 | — | $247.54 M | — | -76.11% | -5.76% | $5.45 | $2.17 |
| 254 | Cabaletta Bio, Inc. | $1.47 | — | $246.69 M | — | -149.87% | -128.27% | $4.23 | $1.39 |
| 255 | Larimar Therapeutics, Inc. | $2.35 | — | $244.12 M | — | -212.84% | -137.39% | $6.42 | $1.92 |
| 256 | Immuneering Corporation | $3.73 | — | $241.32 M | — | -26.76% | -27.15% | $8.48 | $3.38 |
| 257 | Vanda Pharmaceuticals Inc. | $4.01 | — | $238.53 M | — | -43.97% | -84.95% | $9.94 | $3.96 |
| 258 | Lexeo Therapeutics, Inc. | $2.8 | — | $237.23 M | — | -85.23% | -41.85% | $10.99 | $2.55 |
| 259 | Palisade Bio, Inc. | $1.33 | — | $233.52 M | — | -13.92% | -33.47% | $2.85 | $1.32 |
| 260 | Greenwich LifeSciences, Inc. | $16.03 | — | $231.84 M | — | -631.87% | -793.76% | $34.1 | $7.78 |
| 261 | MacroGenics, Inc. | $2.25 | — | $231.23 M | — | -34.08% | -31.27% | $5.08 | $1.29 |
| 262 | Lyell Immunopharma, Inc. | $9.39 | — | $230.1 M | — | -69.37% | -91.62% | $45 | $7.2 |
| 263 | BridgeBio Oncology Therapeutics, Inc. | $2.66 | 148.58 | $228.5 M | — | -35.28% | -46.9% | $14.87 | $2.66 |
| 264 | Sol-Gel Technologies Ltd. | $69.45 | — | $226.72 M | — | -31.74% | -44.05% | $97.97 | $28.81 |
| 265 | Keros Therapeutics, Inc. | $11.28 | 2.55 | $222.56 M | — | 21.27% | -21.4% | $22.55 | $9.69 |
| 266 | Inhibikase Therapeutics, Inc. | $1.59 | — | $221.86 M | — | -30.85% | -46.9% | $2.61 | $1.33 |
| 267 | Zentalis Pharmaceuticals, Inc. | $2.21 | — | $213.18 M | — | -57.45% | -52.77% | $6.95 | $1.21 |
| 268 | CAMP4 THERAPEUTICS CORPORATION | $3.3 | — | $212.73 M | — | -50.89% | -194.74% | $7.75 | $2.9 |
| 269 | ProQR Therapeutics N.V. | $1.29 | — | $210.18 M | — | -54.09% | -75.23% | $3 | $1.3 |
| 270 | Protalix BioTherapeutics, Inc. | $2.55 | 10.74 | $203.44 M | — | -9.85% | 31.61% | $3.19 | $1.65 |
| 271 | Pyxis Oncology, Inc. | $1.68 | — | $200.9 M | — | -119.93% | -101.77% | $5.55 | $1.03 |
| 272 | Satellos Bioscience Inc. | $6.42 | — | $193.49 M | — | -95.23% | -71.97% | $18.98 | $7.56 |
| 273 | Niagen Bioscience, Inc. | $2.43 | 12.05 | $192.67 M | — | 16.53% | 20.5% | $7.95 | $2.42 |
| 274 | Cartesian Therapeutics, Inc. | $6.18 | — | $189.4 M | — | -30.8% | -3215.82% | $11 | $5.6 |
| 275 | Evommune, Inc. | $5.1 | — | $189.08 M | — | -39.16% | -46.76% | $33.2 | $5.09 |
| 276 | ADC Therapeutics SA | $1.44 | — | $188.31 M | — | -42.38% | -229.23% | $4.98 | $0.78 |
| 277 | Eledon Pharmaceuticals, Inc. | $2.3 | — | $186.9 M | — | -55.26% | -98.48% | $4.6 | $1.35 |
| 278 | Whitehawk Therapeutics, Inc. | $3.21 | — | $183.21 M | — | -83.93% | -53.89% | $5.5 | $1.97 |
| 279 | Precision BioSciences, Inc. | $6.64 | — | $182.45 M | — | -35.84% | -91.6% | $9.62 | $3.53 |
| 280 | Atrium Therapeutics, Inc. | $8.2 | — | $181.77 M | — | -32.47% | -40.3% | $73.06 | $7.49 |
| 281 | Compugen Ltd. | $1.94 | 5.14 | $180.93 M | — | 23.38% | 42.57% | $3.23 | $1.43 |
| 282 | Invivyd, Inc. | $0.61 | — | $180.81 M | — | -22.89% | -59.73% | $3.07 | $0.53 |
| 283 | Korro Bio, Inc. | $11.98 | — | $180.68 M | — | -85.99% | -114.26% | $42.92 | $5.2 |
| 284 | Alpha Cognition Inc. Common Stock | $8.34 | — | $179.01 M | — | -23.03% | -45.33% | $10.14 | $4.5 |
| 285 | PepGen Inc. | $2.52 | — | $174.53 M | — | -58.05% | -51.01% | $7.8 | $1.31 |
| 286 | Sionna Therapeutics, Inc. | $3.6 | — | $171.81 M | — | -28.32% | -32.94% | $54.97 | $3.64 |
| 287 | Entrada Therapeutics, Inc. | $4.41 | — | $171.71 M | — | -44.74% | -57.61% | $16.45 | $4.11 |
| 288 | Oramed Pharmaceuticals Inc. | $4.13 | 0.98 | $171.38 M | — | -7.12% | 72.96% | $5.47 | $2.09 |
| 289 | Upstream Bio, Inc. | $2.74 | — | $163.77 M | — | -47.12% | -48.4% | $33.68 | $2.7 |
| 290 | Tiziana Life Sciences Ltd | $0.95 | — | $162.98 M | — | -401.27% | -398.42% | $2.1 | $0.76 |
| 291 | Coherus Oncology, Inc. | $1.01 | 1.05 | $162.23 M | — | -155.52% | -183.36% | $2.62 | $0.94 |
| 292 | NervGen Pharma Corp. | $1.43 | — | $161.94 M | — | -721.31% | -399.62% | $8.49 | $3.2 |
| 293 | ALX Oncology Holdings Inc. | $1.17 | — | $161.78 M | — | -292.37% | -90.3% | $2.66 | $0.86 |
| 294 | MediWound Ltd. | $12 | — | $157.25 M | — | -41.75% | -47.24% | $19.7 | $11.84 |
| 295 | Sutro Biopharma, Inc. | $9.33 | — | $154.04 M | — | -106.34% | -223.84% | $43.85 | $7.15 |
| 296 | Canton Strategic Holdings, Inc. | $1.86 | — | $148.21 M | — | -3.9% | -29.54% | $6.89 | $1.66 |
| 297 | Codexis, Inc. | $1.28 | — | $143.45 M | — | -31.3% | -74.36% | $2.98 | $0.96 |
| 298 | Acumen Pharmaceuticals, Inc. | $1.98 | — | $143.19 M | — | -133.4% | -136.27% | $3.6 | $1.5 |
| 299 | TuHURA Biosciences, Inc. | $2.18 | — | $138.92 M | 0.01% | -120.19% | -154.27% | $3.43 | $0.41 |
| 300 | Protara Therapeutics, Inc. | $2.33 | — | $137.69 M | — | -32.51% | -41.72% | $7.82 | $2.29 |
| 301 | Compass Therapeutics, Inc. | $0.76 | — | $137.05 M | — | -35.42% | -29.94% | $6.88 | $0.78 |
| 302 | Armata Pharmaceuticals, Inc. | $3.64 | — | $136.09 M | — | -45.96% | -120% | $16.34 | $2.75 |
| 303 | AN2 Therapeutics, Inc. | $3.55 | — | $133.96 M | — | -71.59% | -53.52% | $7.19 | $1 |
| 304 | Cue Biopharma, Inc. | $18.66 | — | $132.87 M | — | -92.35% | -1032.19% | $45.5 | $4.97 |
| 305 | Spruce Biosciences, Inc. | $45.15 | — | $129.76 M | — | -85.04% | -155.4% | $144 | $38.06 |
| 306 | Outlook Therapeutics, Inc. | $0.52 | — | $128.32 M | — | 246.27% | -415.51% | $2.54 | $0.16 |
| 307 | Nkarta, Inc. | $1.79 | — | $127.13 M | — | -31.94% | -39.64% | $3.72 | $1.7 |
| 308 | Lixte Biotechnology Holdings, Inc. | $3.82 | — | $125.36 M | — | -431.9% | -124.69% | $8.38 | $2.36 |
| 309 | Anavex Life Sciences Corp. | $1.33 | — | $120.97 M | — | -54.15% | -11.43% | $9.5 | $1.14 |
| 310 | Humacyte, Inc. | $0.44 | — | $120.95 M | — | -110.35% | -516.75% | $1.78 | $0.34 |
| 311 | Foghorn Therapeutics Inc. | $2 | — | $118.77 M | — | -59.34% | -301.61% | $7.61 | $1.79 |
| 312 | PDS Biotechnology Corporation | $1.11 | — | $114.98 M | — | -150.13% | -346.03% | $1.79 | $0.2 |
| 313 | Minerva Neurosciences, Inc. | $2.3 | — | $114.59 M | — | -15.79% | -169.62% | $8.8 | $2.24 |
| 314 | Seer, Inc. | $1.97 | — | $109.08 M | — | -27.82% | -27.23% | $2.41 | $1.55 |
| 315 | Unicycive Therapeutics, Inc. | $3.89 | — | $108.36 M | — | -97.75% | -88.81% | $8.74 | $3.35 |
| 316 | Black Diamond Therapeutics, Inc. | $1.88 | 7.22 | $108.3 M | — | 15.61% | -38.8% | $4.94 | $1.6 |
| 317 | Cibus, Inc. | $1.41 | — | $107.01 M | — | -23.41% | -320.6% | $4.19 | $1.09 |
| 318 | vTv Therapeutics Inc. | $25.55 | 55.59 | $106.59 M | — | -39.41% | -6.27% | $44 | $19.5 |
| 319 | Voyager Therapeutics, Inc. | $1.74 | — | $106.09 M | — | -58.41% | -57.92% | $5.48 | $1.75 |
| 320 | enGene Therapeutics Inc. | $1.56 | — | $105.89 M | — | -65% | -55.79% | $12.25 | $1.4 |
| 321 | PolyPid Ltd. | $5.25 | — | $105.21 M | — | -226.3% | -311.07% | $5.73 | $3.1 |
| 322 | Anixa Biosciences, Inc. | $2.99 | — | $104.29 M | — | -82.91% | -70.17% | $5.46 | $2.32 |
| 323 | NRx Pharmaceuticals, Inc. | $2.49 | — | $103.04 M | — | 103.85% | -195.76% | $5.05 | $1.62 |
| 324 | Coeptis Therapeutics Holdings Inc | $3.95 | — | $102.06 M | — | -90.67% | -641.09% | $21.41 | $2.11 |
| 325 | OnKure Therapeutics, Inc. | $2.52 | — | $102.05 M | — | -112.02% | -49.02% | $5.38 | $2.01 |
| 326 | Immunic, Inc. | $7.41 | — | $101.11 M | — | 1572.16% | -95.67% | $17.43 | $5.06 |
| 327 | Vivani Medical, Inc. | $1.11 | — | $101.02 M | — | -84.04% | -191.05% | $1.81 | $0.92 |
| 328 | Fortress Biotech, Inc. | $2.99 | 0.93 | $99.33 M | — | — | 1.1% | $4.53 | $1.7 |
| 329 | LENZ Therapeutics, Inc. | $3.16 | — | $99.29 M | — | -32.01% | -43.72% | $34.27 | $3.12 |
| 330 | OKYO Pharma Limited | $1.4 | — | $98.22 M | — | 127.79% | -51.58% | $3.2 | $1.26 |
| 331 | Coya Therapeutics, Inc. | $3.94 | — | $97.12 M | — | -51.17% | -53.32% | $7.55 | $3.71 |
| 332 | Polaryx Therapeutics, Inc. | $1.85 | — | $96.7 M | — | -171.33% | -644.23% | $48.91 | $1.83 |
| 333 | PMV Pharmaceuticals, Inc. | $1.27 | — | $95.9 M | — | -81.99% | -78.11% | $1.91 | $1.02 |
| 334 | NeurAxis, Inc. | $7.4 | — | $95.44 M | — | -216.78% | -169.07% | $9.33 | $2.21 |
| 335 | Atara Biotherapeutics, Inc. | $8.59 | 2.5 | $94.66 M | — | 674.99% | -315.42% | $19.14 | $3.92 |
| 336 | Oncolytics Biotech Inc. | $0.5 | — | $94.18 M | — | -1939.57% | -440.39% | $4.49 | $1.48 |
| 337 | VYNE Therapeutics Inc. | $28.68 | — | $93.5 M | — | -107.15% | -89.1% | $46.95 | $16.04 |
| 338 | ImmuCell Corporation | $10.25 | 118.23 | $93.09 M | — | 4.28% | 2.68% | $12.1 | $4.52 |
| 339 | Genelux Corporation | $2 | — | $89.59 M | — | -259.44% | -205.85% | $8.54 | $1.96 |
| 340 | Rallybio Corporation | $16.64 | 1.94 | $88.4 M | — | -56.97% | 68.56% | $17.57 | $3.67 |
| 341 | Tonix Pharmaceuticals Holding Corp. | $5.17 | — | $87.98 M | — | -49.81% | -68.99% | $20.58 | $5.05 |
| 342 | Tenaya Therapeutics, Inc. | $0.39 | — | $87.23 M | — | -70.98% | -108.05% | $1.84 | $0.36 |
| 343 | Aardvark Therapeutics, Inc. | $1.39 | — | $86.45 M | — | -58.82% | -71.54% | $16.6 | $3.35 |
| 344 | Inovio Pharmaceuticals, Inc. | $0.9 | — | $86.43 M | — | -283.35% | -190.5% | $2.72 | $0.56 |
| 345 | NeOnc Technologies Holdings, Inc. | $3.27 | — | $84.98 M | — | 129% | 122.08% | $12 | $2.5 |
| 346 | Rani Therapeutics Holdings, Inc. | $0.61 | — | $84.46 M | — | -83.37% | -73.71% | $3.87 | $0.57 |
| 347 | Milestone Pharmaceuticals Inc. | $0.65 | — | $80.86 M | — | -62.4% | -288.36% | $3.06 | $0.69 |
| 348 | ProMIS Neurosciences, Inc. | $8.34 | — | $80.53 M | — | 3267.2% | -79.35% | $27.4 | $6.27 |
| 349 | Corbus Pharmaceuticals Holdings, Inc. | $4.05 | — | $77.75 M | — | -57.84% | -87.05% | $19.55 | $4.03 |
| 350 | Equillium, Inc. | $1.23 | — | $76.72 M | — | -81.63% | -61.43% | $3.54 | $0.76 |
| 351 | Neumora Therapeutics, Inc. | $0.38 | — | $76.23 M | — | -152.06% | -242.28% | $3.65 | $0.32 |
| 352 | Acrivon Therapeutics, Inc. | $1.73 | — | $75.42 M | — | -73.75% | -70.14% | $3.56 | $1.27 |
| 353 | Pelthos Therapeutics Inc. | $17 | — | $75 M | — | -31.06% | -78.04% | $37.5 | $18.19 |
| 354 | Annovis Bio, Inc. | $1.75 | — | $74.45 M | — | — | -2.21% | $5.5 | $1.54 |
| 355 | Telomir Pharmaceuticals, Inc. | $0.98 | — | $74.35 M | — | -178.22% | -102.69% | $1.58 | $0.89 |
| 356 | Cingulate Inc. | $4.98 | — | $72.42 M | — | -418.81% | -238.41% | $11.89 | $3.16 |
| 357 | Cardiff Oncology, Inc. | $0.91 | — | $70.71 M | — | -107.63% | -103.08% | $3.31 | $0.76 |
| 358 | Nutriband Inc. | $5.76 | — | $70.02 M | — | -103.12% | -109.02% | $9.19 | $2.8 |
| 359 | MAIA Biotechnology, Inc. | $1.15 | — | $69.77 M | — | -618.06% | -211.15% | $3.19 | $0.87 |
| 360 | MediciNova, Inc. | $1.39 | — | $68.91 M | — | -31.77% | -26.51% | $3.9 | $1.17 |
| 361 | Cognition Therapeutics, Inc. | $0.72 | — | $68.35 M | — | -70.77% | -50.17% | $1.83 | $0.55 |
| 362 | Tenax Therapeutics, Inc. | $1.72 | — | $64.93 M | — | -58.09% | -61.55% | $19.4 | $1.31 |
| 363 | Champions Oncology, Inc. | $4.72 | — | $64.86 M | — | 57.07% | -27.12% | $8.31 | $4.59 |
| 364 | Spero Therapeutics, Inc. | $1.11 | 8.68 | $64.06 M | — | 11.92% | 16.17% | $3.08 | $1.08 |
| 365 | Apollomics, Inc. | $21.84 | — | $63.66 M | — | -737.55% | -693.39% | $36.52 | $10.01 |
| 366 | Verrica Pharmaceuticals Inc. | $3.53 | — | $62.5 M | — | -38.9% | -205.58% | $9.82 | $3.28 |
| 367 | XBiotech Inc. | $1.93 | — | $58.76 M | — | -39.17% | -31.62% | $3.44 | $1.91 |
| 368 | OS Therapies Incorporated | $1.25 | — | $58.51 M | — | 582.87% | -567.59% | $2.25 | $1.15 |
| 369 | RenovoRx, Inc. | $1.29 | — | $58.22 M | — | -176.68% | -145.63% | $2.59 | $0.7 |
| 370 | Gossamer Bio, Inc. | $9.61 | — | $57.93 M | — | -150.03% | -118.77% | $309.6 | $8.29 |
| 371 | Caribou Biosciences, Inc. | $0.53 | — | $57.12 M | — | -90.82% | -89.11% | $3.54 | $0.44 |
| 372 | Heron Therapeutics, Inc. | $0.3 | — | $56.23 M | — | -1.59% | -300.9% | $1.58 | $0.26 |
| 373 | Boundless Bio, Inc. | $2.36 | — | $55.51 M | — | -43.97% | -70.89% | $3.16 | $0.96 |
| 374 | Gain Therapeutics, Inc. | $1.26 | — | $54.99 M | — | -96.12% | -161.58% | $4.34 | $1.15 |
| 375 | MiNK Therapeutics, Inc. | $10.71 | — | $54.65 M | — | 859.68% | -168.87% | $16.93 | $8.48 |
| 376 | Kezar Life Sciences, Inc. | $0 | — | $53.86 M | — | -74.59% | -64.42% | $7.55 | $5.95 |
| 377 | Xilio Therapeutics, Inc. | $7.57 | — | $53.73 M | — | -42.66% | -9.23% | $12.58 | $6.47 |
| 378 | Pliant Therapeutics, Inc. | $0.86 | — | $53.59 M | — | -74.87% | -69.56% | $1.95 | $0.85 |
| 379 | Dogwood Therapeutics, Inc. | $1.55 | 1.32 | $52.13 M | — | — | -0.35% | $9.5 | $1.28 |
| 380 | NovaBay Pharmaceuticals Inc | $1.27 | — | $51.92 M | 0% | -96.1% | -109.37% | $99.75 | $0.78 |
| 381 | Elicio Therapeutics, Inc. | $1.9 | — | $51.47 M | — | -210.11% | -582.97% | $16 | $1.44 |
| 382 | Rein Therapeutics Inc. | $0.58 | — | $51.06 M | — | -121.99% | -153.23% | $2.18 | $0.54 |
| 383 | Actinium Pharmaceuticals, Inc. | $1.52 | 4.45 | $50.31 M | — | -82.74% | 83.42% | $1.74 | $0.74 |
| 384 | Connect Biopharma Holdings Limited | $0.77 | — | $48.27 M | — | -24.19% | -165.41% | $3.82 | $0.73 |
| 385 | ImageneBio, Inc. | $4.22 | — | $47.9 M | — | -34.18% | -38.99% | $9.1 | $3.9 |
| 386 | iBio, Inc. | $0.72 | — | $47.71 M | — | -108.92% | -47.92% | $3.82 | $0.73 |
| 387 | Werewolf Therapeutics, Inc. | $0.98 | — | $47.63 M | — | -182.5% | -166.98% | $1.83 | $0.27 |
| 388 | LeonaBio, Inc. | $4.84 | — | $45.6 M | — | -76.55% | -411.58% | $14.21 | $2.21 |
| 389 | Hyperion DeFi, Inc. | $2.8 | 6.62 | $44.05 M | — | -38.69% | 9.77% | $9.13 | $2.34 |
| 390 | Serina Therapeutics, Inc. | $1.65 | — | $43.94 M | — | -709.03% | -106.79% | $5.29 | $1.22 |
| 391 | Biomea Fusion, Inc. | $0.6 | — | $43.5 M | — | -171.28% | -171.19% | $2.24 | $0.68 |
| 392 | Estrella Immunopharma, Inc. | $0.98 | — | $42.85 M | — | 126.01% | -259.11% | $3.15 | $0.24 |
| 393 | Kalaris Therapeutics, Inc. | $1.87 | — | $41.5 M | — | -41.2% | -71.71% | $11.88 | $1.87 |
| 394 | Grace Therapeutics, Inc. | $1.93 | — | $41.02 M | — | -23.81% | -33.73% | $5.18 | $1.79 |
| 395 | INmune Bio Inc. | $1.46 | — | $40.52 M | — | -128.97% | -82.87% | $2.6 | $1.09 |
| 396 | Tevogen Bio Holdings Inc. | $9.46 | — | $39.91 M | — | — | — | $71 | $4.13 |
| 397 | Instil Bio, Inc. | $5.84 | — | $39.61 M | — | -26.15% | -26.78% | $20.11 | $5.62 |
| 398 | Aldeyra Therapeutics, Inc. | $0.65 | — | $38.93 M | — | -79.69% | -53.14% | $5.93 | $0.63 |
| 399 | GridAI Technologies Corp. | $5.61 | — | $38.51 M | — | -27% | -56.79% | $6.93 | $1.87 |
| 400 | Veru Inc. | $2.24 | — | $38.37 M | — | -161.13% | -45.89% | $7.33 | $2.05 |
| 401 | MindWalk Holdings Corp. | $1.16 | — | $38.19 M | — | -34.42% | -133.33% | $2.99 | $0.99 |
| 402 | Adicet Bio, Inc. | $3.99 | — | $37.35 M | — | -71.49% | -74.9% | $14.98 | $4.21 |
| 403 | Edesa Biotech, Inc. | $2.77 | — | $36.62 M | — | -57.24% | -124.21% | $20.32 | $0.72 |
| 404 | eXoZymes, Inc. | $4 | — | $36.2 M | — | -220.6% | -292.13% | $18.4 | $3.71 |
| 405 | Lite Strategy, Inc. | $1.16 | — | $35.88 M | 0% | -103.09% | -68.86% | $2.26 | $0.69 |
| 406 | NanoViricides, Inc. | $1.4 | — | $35.48 M | — | -127.59% | -91.11% | $2.23 | $0.85 |
| 407 | EyePoint, Inc. | $0.4 | — | $35.02 M | — | -74.45% | -135.81% | $19.11 | $0.39 |
| 408 | CervoMed Inc. | $2.31 | — | $34.55 M | — | -155.27% | -156.02% | $10 | $2.13 |
| 409 | Impact BioMedical Inc. | $3.6 | 41.15 | $32.47 M | — | -26.29% | 19.45% | $10.47 | $2.43 |
| 410 | Quince Therapeutics, Inc. | $33.08 | — | $32.27 M | — | -33.74% | -127.02% | $910 | $15.1 |
| 411 | Filana Therapeutics, Inc. | $0.64 | — | $31.31 M | — | -128.99% | -58.78% | $2.27 | $0.64 |
| 412 | Celularity Inc. | $0.98 | — | $31.16 M | — | -48.8% | -272.44% | $2.55 | $0.56 |
| 413 | Evaxion A/S | $3.76 | — | $30.94 M | — | -38.23% | -72.61% | $6.92 | $2.72 |
| 414 | Metagenomi Therapeutics, Inc. | $0.81 | — | $30.83 M | — | -48.45% | -51.23% | $3.21 | $0.77 |
| 415 | Hoth Therapeutics, Inc. | $0.5 | — | $30.69 M | — | -200.97% | -165.25% | $2.45 | $0.48 |
| 416 | TransCode Therapeutics, Inc. | $1.77 | — | $29.97 M | — | -334.68% | -39.28% | $15.33 | $1.52 |
| 417 | Aligos Therapeutics, Inc. | $4.78 | — | $29.85 M | — | -130.74% | -160.72% | $13.69 | $3.98 |
| 418 | CEL-SCI Corporation | $1.64 | — | $28.49 M | — | -107.75% | -202.14% | $9.35 | $0.89 |
| 419 | ABVC BioPharma, Inc. | $1.04 | — | $27.76 M | — | -48% | -71.47% | $3.06 | $0.71 |
| 420 | Quantum BioPharma Ltd. | $2.24 | — | $27.74 M | — | -300.19% | -417.21% | $23.1 | $2.85 |
| 421 | Plus Therapeutics, Inc. | $1.65 | — | $26.64 M | — | -381.4% | -83.36% | $18.88 | $1.49 |
| 422 | Atossa Therapeutics, Inc. | $2.6 | — | $26.25 M | — | -94.38% | -102.99% | $14.85 | $1.7 |
| 423 | IGC Pharma, Inc. | $0.25 | — | $25.73 M | — | -114.73% | -113.58% | $0.45 | $0.23 |
| 424 | BriaCell Therapeutics Corp. | $2.9 | — | $25.23 M | — | — | -1.75% | $31.6 | $2.6 |
| 425 | Neuphoria Therapeutics Inc. | $4.31 | — | $23.29 M | — | — | -0.63% | $21.4 | $3.65 |
| 426 | NextCure, Inc. | $4.98 | — | $22.41 M | — | -145.43% | -175.46% | $15.74 | $1.55 |
| 427 | Context Therapeutics Inc. | $0.24 | — | $21.99 M | — | -65.65% | -82.06% | $3.62 | $0.22 |
| 428 | Kyntra Bio, Inc. | $4.58 | 0.12 | $21.14 M | — | -50.18% | -290.91% | $11.65 | $4.85 |
| 429 | Polyrizon Ltd. | $8.73 | — | $20.69 M | — | -27.56% | -17.84% | $18.2 | $2.88 |
| 430 | Seres Therapeutics, Inc. | $2.09 | 12.68 | $20.48 M | — | -79.05% | -60.32% | $29.98 | $2.02 |
| 431 | Sensei Biotherapeutics, Inc. | $33.4 | — | $19.5 M | — | -119.5% | -283.67% | $42.14 | $7.45 |
| 432 | Cocrystal Pharma, Inc. | $0.95 | — | $18.4 M | — | -120.22% | -207.47% | $2.03 | $0.76 |
| 433 | BeyondSpring Inc. | $0.43 | — | $17.68 M | — | -72.39% | -133.13% | $2.44 | $0.42 |
| 434 | Jasper Therapeutics, Inc. | $0.51 | — | $16.68 M | — | -371.51% | -618.87% | $2.57 | $0.32 |
| 435 | aTyr Pharma, Inc. | $0.17 | — | $16.24 M | — | -99.71% | -99.62% | $1.11 | $0.17 |
| 436 | Marker Therapeutics, Inc. | $0.96 | — | $16.21 M | — | -74.05% | -80.86% | $2.46 | $0.84 |
| 437 | Dyadic International, Inc. | $0.4 | — | $16.03 M | — | -114.18% | -350.86% | $1.6 | $0.34 |
| 438 | Psyence Biomedical Ltd. | $4.17 | 51.19 | $15.89 M | — | -54.49% | -53.38% | $134.38 | $1.92 |
| 439 | Fractyl Health, Inc. | $1.08 | — | $14.99 M | — | -93.93% | -852.14% | $29.34 | $1.11 |
| 440 | NewcelX Ltd. | $2.66 | — | $14.32 M | — | 23.66% | -135.12% | $16.6 | $1.83 |
| 441 | BioCardia, Inc. | $0.92 | — | $13.94 M | — | -843.83% | -221.68% | $1.8 | $0.75 |
| 442 | TScan Therapeutics, Inc. | $0.2 | — | $13.77 M | — | -64.64% | -108.72% | $2.43 | $0.2 |
| 443 | Allarity Therapeutics, Inc. | $0.87 | — | $13.77 M | — | -148.49% | -152.77% | $1.84 | $0.77 |
| 444 | Pasithea Therapeutics Corp. | $0.4 | — | $13.53 M | — | -37.74% | -49.49% | $2.06 | $0.28 |
| 445 | Daré Bioscience, Inc. | $0.65 | — | $13.1 M | — | -154.2% | -373.17% | $3.78 | $0.67 |
| 446 | Tvardi Therapeutics, Inc. | $0.94 | — | $12.97 M | — | -127.18% | -145.4% | $5.9 | $0.93 |
| 447 | Vyome Holdings, Inc. | $1.79 | — | $12.56 M | — | -73.02% | -254.62% | $6.56 | $1.75 |
| 448 | SeaStar Medical Holding Corporation | $2.41 | — | $12.56 M | — | -116.89% | -162.75% | $6.48 | $2.07 |
| 449 | Pluri Inc. | $0.99 | — | $12.49 M | — | -348.95% | -53.15% | $4.87 | $0.85 |
| 450 | Actuate Therapeutics, Inc. Common stock | $0.48 | — | $12.4 M | — | -270.08% | -346.18% | $7.9 | $0.41 |
| 451 | Karyopharm Therapeutics Inc. | $0.52 | — | $12.39 M | — | -554.58% | -182.43% | $10.99 | $0.31 |
| 452 | Aspire Biopharma Holdings, Inc. | $8.8 | — | $12.34 M | — | 308.11% | -57.48% | $562.8 | $3.31 |
| 453 | Bolt Biotherapeutics, Inc. | $6.27 | — | $12.08 M | — | -71.68% | -126.23% | $7.2 | $3.1 |
| 454 | Lipocine Inc. | $1.44 | — | $12.04 M | — | -71.64% | -64.75% | $12.37 | $1.4 |
| 455 | AEON Biopharma, Inc. | $0.24 | — | $11.97 M | — | 252.78% | -1.74% | $1.45 | $0.18 |
| 456 | GT Biopharma, Inc. | $5.46 | — | $11.25 M | — | -214.65% | -443.08% | $28.75 | $4.91 |
| 457 | Cellectar Biosciences, Inc. | $1.22 | — | $11.06 M | — | -224.66% | -165.71% | $4.7 | $1.12 |
| 458 | Citius Pharmaceuticals, Inc. | $0.4 | — | $10.98 M | — | -44.79% | -67.15% | $1.98 | $0.39 |
| 459 | Passage Bio, Inc. | $3.37 | — | $10.84 M | — | -110.08% | -218.59% | $20 | $3.29 |
| 460 | YD Bio Ltd | $4.95 | — | $10.76 M | — | -22.15% | 149.77% | $18.66 | $1.7 |
| 461 | Lisata Therapeutics, Inc. | $1 | — | $10.59 M | — | -124.1% | -75.1% | $5.07 | $0.96 |
| 462 | BioVie Inc. | $1.24 | — | $10.58 M | — | -93.67% | -126.02% | $3.79 | $0.82 |
| 463 | Adial Pharmaceuticals, Inc. | $3.92 | — | $10.44 M | — | -147.82% | -1693.21% | $9.75 | $1.31 |
| 464 | Intensity Therapeutics, Inc. | $3.25 | — | $10.41 M | — | -100.14% | -116.61% | $43.5 | $3.09 |
| 465 | IN8bio, Inc. | $1.05 | — | $10.35 M | — | -68.2% | -91.18% | $2.73 | $0.88 |
| 466 | Phio Pharmaceuticals Corp. | $0.85 | — | $10.26 M | — | -45.76% | -87.41% | $4.19 | $0.81 |
| 467 | Kiora Pharmaceuticals, Inc. | $2.29 | — | $10.13 M | — | -45.87% | -63.39% | $2.91 | $1.76 |
| 468 | Ensysce Biosciences, Inc. | $0.47 | — | $9.53 M | — | -355% | -374.96% | $2.56 | $0.23 |
| 469 | Palatin Technologies, Inc. | $5.11 | — | $9.53 M | — | 478.76% | -115% | $31 | $5.4 |
| 470 | Lantern Pharma Inc. | $0.64 | — | $9.26 M | — | -275.14% | -198.35% | $4.34 | $0.6 |
| 471 | MetaVia Inc. | $1.38 | — | $9.09 M | — | -250.37% | -209.67% | $14.85 | $0.97 |
| 472 | Theriva Biologics, Inc. | $0.2 | — | $8.95 M | — | -85.21% | -93.49% | $0.85 | $0.16 |
| 473 | Tempest Therapeutics, Inc. | $0.51 | — | $8.61 M | — | -195.16% | -729.89% | $11.13 | $0.52 |
| 474 | CytoMed Therapeutics Limited | $0.92 | — | $8.5 M | — | -33.09% | -60.9% | $3.68 | $0.68 |
| 475 | CalciMedica, Inc. | $1.23 | — | $8.4 M | — | -235.71% | -138.8% | $36 | $1 |
| 476 | Vistagen Therapeutics, Inc. | $0.18 | — | $8.36 M | — | -78.03% | -152.59% | $5.14 | $0.19 |
| 477 | Curanex Pharmaceuticals Inc | $4.64 | — | $8.15 M | — | -37.04% | -109.11% | $16.94 | $3.58 |
| 478 | Soligenix, Inc. | $0.36 | — | $7.84 M | — | -213.96% | -181.02% | $1.7 | $0.28 |
| 479 | CNS Pharmaceuticals, Inc. | $4.97 | — | $7.31 M | — | -241.26% | -204.25% | $10.54 | $1.9 |
| 480 | OSR Holdings, Inc. | $0.21 | — | $7.29 M | — | 79.82% | -11.67% | $0.9 | $0.07 |
| 481 | Alaunos Therapeutics, Inc. | $2.28 | — | $7.29 M | — | -233.25% | -232.6% | $4.5 | $0.72 |
| 482 | Exicure, Inc. | $1.05 | — | $7.14 M | — | -99.65% | -237.91% | $9.48 | $0.94 |
| 483 | CollPlant Biotechnologies Ltd. | $3.67 | — | $6.84 M | — | -141.54% | -160.28% | $26 | $2.64 |
| 484 | Skye Bioscience, Inc. | $1.54 | — | $6.82 M | — | -289.25% | -217.27% | $13.28 | $1.5 |
| 485 | FibroBiologics, Inc. | $0.95 | — | $6.79 M | — | -211.82% | -536.78% | $9.6 | $0.62 |
| 486 | Imunon, Inc. | $1.24 | — | $6.79 M | — | -191.16% | -314.9% | $5.1 | $0.96 |
| 487 | Evogene Ltd. | $0.36 | — | $6.69 M | — | -84.53% | -38.31% | $1.33 | $0.35 |
| 488 | Lexaria Bioscience Corp. | $3.08 | — | $6.49 M | — | -443.04% | -160.72% | $21.6 | $2.43 |
| 489 | AIM ImmunoTech Inc. | $0.16 | — | $6.37 M | — | 2638.91% | -138.03% | $2.79 | $0.16 |
| 490 | Aprea Therapeutics, Inc. | $0.52 | — | $6.36 M | — | -100.49% | -46.3% | $1.64 | $0.51 |
| 491 | Acurx Pharmaceuticals, Inc. | $1.14 | — | $6.31 M | — | -153.59% | -124.74% | $7.54 | $1.07 |
| 492 | Enveric Biosciences, Inc. | $1.4 | — | $6.27 M | — | -210.04% | -168.05% | $13.25 | $1.17 |
| 493 | Bio Green Med Solution, Inc. | $0.96 | — | $6.13 M | 0.02% | 552.16% | -31.6% | $2.95 | $0.57 |
| 494 | Moleculin Biotech, Inc. | $6.5 | — | $6.12 M | — | -164.37% | -35.39% | $315 | $3.23 |
| 495 | Reviva Pharmaceuticals Holdings, Inc. | $0.45 | — | $5.87 M | — | -233.59% | -111.82% | $15.4 | $0.26 |
| 496 | Senti Biosciences Holdings, Inc. | $0.19 | — | $5.87 M | — | -171.08% | -503.79% | $2.88 | $0.19 |
| 497 | Aptorum Group Limited | $4.82 | — | $5.7 M | — | -12.89% | -9.33% | $17.2 | $4.65 |
| 498 | Lakewood-Amedex Biotherapeutics, Inc. | $0.39 | — | $5.53 M | — | — | — | $9.82 | $0.37 |
| 499 | Alzamend Neuro, Inc. | $1.13 | — | $5.45 M | — | -113.32% | -277.88% | $2.68 | $0.84 |
| 500 | Pulmatrix, Inc. | $1.48 | — | $5.42 M | — | -135.67% | -96.97% | $5.08 | $1.16 |
| 501 | Traws Pharma, Inc. | $0.34 | 2.49 | $5.23 M | — | -185.49% | -225.02% | $3.23 | $0.36 |
| 502 | Longeveron Inc. | $1.6 | — | $5.1 M | — | -377.18% | -223.19% | $12.3 | $1.31 |
| 503 | Processa Pharmaceuticals, Inc. | $1.81 | — | $5.06 M | — | -250.81% | -281.3% | $10.84 | $1.04 |
| 504 | Cardio Diagnostics Holdings, Inc. | $1.69 | — | $5 M | — | -90.54% | -82.27% | $7.91 | $0.97 |
| 505 | Creative Medical Technology Holdings, Inc. | $0.74 | — | $4.88 M | — | -81.64% | -86.7% | $6.25 | $0.62 |
| 506 | NeuroSense Therapeutics Ltd. | $2.46 | — | $4.67 M | — | -383.35% | -395.28% | $25.4 | $2.15 |
| 507 | Xenetic Biosciences, Inc. | $1.72 | — | $4.47 M | — | -38.33% | -40.62% | $4.94 | $1.85 |
| 508 | Azitra, Inc. | $0.07 | — | $4.33 M | — | -277.12% | -284.75% | $1.09 | $0.05 |
| 509 | Liminatus Pharma, Inc. | $2.94 | — | $4.18 M | — | 30.51% | — | $141.5 | $3.01 |
| 510 | Jaguar Health, Inc. | $2.04 | — | $3.99 M | — | -91.43% | -362.42% | $1,118.25 | $2.15 |
| 511 | Jyong Biotech Ltd. | $1.77 | — | $3.96 M | — | 35.69% | 8.55% | $63 | $1.43 |
| 512 | Jupiter Neurosciences, Inc. | $2.98 | — | $3.93 M | — | -73.72% | -352.06% | $135.75 | $2.25 |
| 513 | Dermata Therapeutics, Inc. | $0.78 | — | $3.87 M | — | -124.91% | -166.67% | $4.66 | $0.6 |
| 514 | PharmaCyte Biotech, Inc. | $0.36 | — | $3.81 M | — | -8.38% | -45.88% | $1.51 | $0.33 |
| 515 | Galmed Pharmaceuticals Ltd. | $3.62 | — | $3.7 M | — | -38.45% | -64.1% | $12.32 | $3.27 |
| 516 | KALA BIO, Inc. | $0.19 | — | $3.66 M | — | -88.86% | -28.16% | $95.5 | $0.11 |
| 517 | Enlivex Ltd. | $0.17 | 0 | $3.51 M | — | -0.65% | 248.08% | $27.15 | $0.19 |
| 518 | Cadrenal Therapeutics, Inc. | $0.96 | — | $3.46 M | — | -491.51% | -406.38% | $14.21 | $0.82 |
| 519 | Ernexa Therapeutics Inc. | $2.06 | — | $3.39 M | 0.59% | -342.48% | -169.4% | $71.5 | $1.84 |
| 520 | GRI Bio, Inc. | $1.45 | — | $3.17 M | — | -198.85% | -134.03% | $64.12 | $1.36 |
| 521 | 60 Degrees Pharmaceuticals, Inc. | $0.87 | — | $3.08 M | — | -220.2% | -211.48% | $8.62 | $0.81 |
| 522 | Clearmind Medicine Inc. | $5.87 | — | $3.03 M | — | -475.2% | -143.79% | $3,840 | $5.25 |
| 523 | Aptevo Therapeutics Inc. | $1.61 | — | $2.91 M | — | -124.44% | -201.49% | $28.44 | $1.37 |
| 524 | BioAtla, Inc. | $1.71 | — | $2.85 M | — | 732.7% | -357.92% | $71.5 | $1.07 |
| 525 | Mustang Bio, Inc. | $0.37 | — | $2.83 M | — | -25.13% | -34.23% | $1.54 | $0.37 |
| 526 | Silexion Therapeutics Corp | $0.19 | — | $2.73 M | — | -260.98% | -563.11% | $35.6 | $0.14 |
| 527 | HCW Biologics Inc. | $1.17 | — | $2.62 M | — | -4764.31% | -19.32% | $24.43 | $1.1 |
| 528 | VivoSim Labs, Inc. | $0.15 | 0.85 | $2.51 M | — | -115.61% | -15.56% | $3.4 | $0.15 |
| 529 | XORTX Therapeutics Inc. | $0.92 | — | $2.37 M | — | -156.2% | -150.08% | $6.1 | $2.42 |
| 530 | Calidi Biotherapeutics, Inc. | $0.64 | — | $2.37 M | — | -410.2% | -372.85% | $27.04 | $0.62 |
| 531 | Decoy Therapeutics Inc. | $0.97 | — | $2.36 M | — | -379.33% | -315.23% | $49.56 | $1.04 |
| 532 | Virax Biolabs Group Limited | $1.22 | — | $2.29 M | — | -107.11% | -77.95% | $21.75 | $1.15 |
| 533 | BioRestorative Therapies, Inc. | $1.62 | — | $2.24 M | — | -4386.1% | -423.84% | $34 | $1.28 |
| 534 | Onconetix, Inc. | $0.42 | — | $2.19 M | — | -40.18% | -91.94% | $200 | $0.38 |
| 535 | Revelation Biosciences, Inc. | $3.79 | — | $2.16 M | — | -94.64% | -100.2% | $40.6 | $3.08 |
| 536 | PMGC Holdings Inc. | $2.71 | — | $2.15 M | — | -76.42% | -118.11% | $1,591.8 | $2.58 |
| 537 | GeoVax Labs, Inc. | $0.21 | — | $2.08 M | — | -498.05% | -743.66% | $15.17 | $0.21 |
| 538 | Propanc Biopharma, Inc. | $0.28 | — | $2.04 M | — | -407.57% | -1743.6% | $27.99 | $0.27 |
| 539 | Silo Pharma, Inc. | $1.18 | — | $1.87 M | — | -61.55% | -81.74% | $10.42 | $1.1 |
| 540 | Kairos Pharma, Ltd. | $0.56 | — | $1.84 M | — | -87.87% | -98.77% | $8.12 | $0.52 |
| 541 | Oragenics, Inc. | $0.42 | — | $1.83 M | — | -113.05% | -59.11% | $1.36 | $0.4 |
| 542 | Matinas BioPharma Holdings, Inc. | $1.7 | — | $1.73 M | — | -202.13% | -137.45% | $25.05 | $1.47 |
| 543 | Valion Bio, Inc. | $0.52 | — | $1.66 M | — | — | -1.82% | $5.6 | $0.51 |
| 544 | Lunai Bioworks Inc. | $0.29 | — | $1.51 M | — | 88.63% | -67% | $13.28 | $0.46 |
| 545 | Genprex, Inc. | $1.81 | — | $1.5 M | — | -194.32% | -163.13% | $249.48 | $1.91 |
| 546 | Artelo Biosciences, Inc. | $2.55 | — | $1.44 M | — | 917.46% | -92.3% | $179.19 | $2.56 |
| 547 | Cybin D/B/A Helus Pharma | $10.19 | — | $1.37 M | — | -60.35% | -77.22% | $20.88 | $5.3 |
| 548 | BiomX Inc. | $0.67 | — | $1.24 M | — | -101.67% | -121.19% | $118.8 | $0.63 |
| 549 | Moolec Science SA | $1.72 | — | $1.22 M | — | 11.2% | -150.93% | $23.22 | $1.48 |
| 550 | Bone Biologics Corporation | $0.39 | — | $1.09 M | — | -60.16% | -57.85% | $2.49 | $0.38 |
| 551 | Curis, Inc. | $0.39 | — | $0.86 M | — | -558.61% | -176.14% | $33.6 | $0.33 |
| 552 | SciSparc Ltd. | $1.09 | — | $0.69 M | — | -80.93% | -287.31% | $37.9 | $1.18 |
| 553 | Aditxt, Inc. | $0.01 | — | $0.4 M | — | -318.91% | -150.77% | $8,125.92 | $0 |
| 554 | IO Biotech, Inc. | $0 | — | $0.22 M | — | -197.41% | -465.36% | $1.23 | $0 |
| 555 | CDT Equity Inc. | $0.13 | — | $0.15 M | — | 230.89% | -22.3% | $20,312.5 | $0.13 |