INDUSTRY
Biotechnology Industry Stocks
The Biotechnology industry covers 555 US-listed companies on StockSifting — NYSE and NASDAQ stocks operating within the Healthcare sector of the American equity market. Companies in the Biotechnology space compete on recurring themes including Treatment, Clinical, Phase, Therapeutics, Disease, which drive revenue growth, margin expansion, and long-term capital allocation decisions across the group. Representative names such as Vertex Pharmaceuticals Incorporated, Regeneron Pharmaceuticals, Inc., Revolution Medicines, Inc., and Alnylam Pharmaceuticals, Inc. show how businesses in this industry pursue differentiated strategies — through proprietary technology, distribution scale, pricing power, brand strength, or regulatory moats — to sustain returns above the cost of capital. For US investors, an industry-level screener is one of the most efficient ways to compare true peers: companies that face the same end-market demand, regulatory framework, raw material costs, and macroeconomic sensitivities, making valuation comparisons far more meaningful than cross-sector analysis. Key metrics to compare across Biotechnology industry stocks include P/E ratio for earnings valuation, ROCE for capital efficiency, ROE for equity profitability, Dividend Yield for income generation, Market Capitalisation for size and liquidity context, and the 52-week trading range for price momentum signals. Use the sortable table below to rank all 555 Biotechnology companies by any fundamental metric and identify which US-listed stocks in this industry offer the most attractive combination of quality, value, and income for your investment portfolio.
How to Analyse Biotechnology Industry Stocks
The Biotechnology industry page on StockSifting is built for US investors who want true peer comparison — businesses facing the same end-market dynamics, regulatory environment, and competitive pressures. Start by sorting the table by ROCE to identify the most capital-efficient operators in the group, then cross-reference with P/E to find high-quality companies available at reasonable valuations. Check Dividend Yield for income-oriented screening and the 52-week High/Low range for price momentum context. Click any company name to open its full profile — including quarterly financials, analyst data, and key ratios — to complete your due diligence before making any investment decision. All data is sourced from NYSE and NASDAQ filings and refreshed daily after US market close.
Key Metrics Explained for Biotechnology Industry Stocks
Every metric in the table below has a specific analytical purpose when comparing Biotechnology industry companies. Understanding what each ratio measures — and what a strong or weak reading looks like within this industry — is essential for making informed investment decisions.
- P/E Ratio (Price-to-Earnings)
- Measures how much investors pay for each dollar of trailing twelve-month earnings. A lower P/E relative to Biotechnology industry peers suggests a cheaper valuation; a higher P/E may reflect premium growth expectations or temporary earnings compression. Always compare P/E within the same industry — cross-sector P/E comparisons are misleading because capital intensity, growth rates, and margin profiles differ structurally.
- Market Capitalisation
- Total market value of a company's outstanding shares (price × shares outstanding). Within the Biotechnology industry, market cap indicates size, liquidity, and index eligibility. Large-cap companies (above $10B) typically offer more analyst coverage and tighter bid-ask spreads; small-caps may offer higher growth potential with commensurately higher risk and lower trading liquidity.
- ROCE — Return on Capital Employed
- Operating profit divided by total capital employed (equity + debt). ROCE is one of the most revealing profitability metrics for Biotechnology industry comparison: it shows which companies generate the most operating profit per dollar of total capital invested. ROCE consistently above 15% signals a strong competitive position; above 25% signals an exceptional business with durable advantages. Companies with high ROCE can self-fund growth and generate superior long-term shareholder returns without requiring continuous equity dilution or heavy borrowing.
- ROE — Return on Equity
- Net income divided by shareholders' equity. ROE measures how efficiently management generates profit from the equity shareholders have invested. In the Biotechnology industry, ROE above 15% is generally considered strong; below 8% raises questions about capital allocation efficiency. Note: high ROE driven by excessive leverage (high D/E ratio) is a warning sign rather than a quality indicator — always check debt levels alongside ROE.
- Dividend Yield
- Annual dividends per share as a percentage of the current share price. For income-oriented US investors, dividend yield is a key criterion — particularly in Biotechnology industry companies with stable, recurring cash flows. A yield significantly above the industry median may indicate an attractive income opportunity or, alternatively, a price decline that warrants further investigation into dividend sustainability. Always verify payout ratio and free cash flow coverage before relying on a high yield as an investment signal.
- 52-Week High / 52-Week Low
- The highest and lowest traded prices over the past 52 weeks. The 52-week range provides immediate context on price momentum and volatility within the Biotechnology industry: stocks trading near their 52-week high may reflect strong business momentum or elevated valuation; stocks near their 52-week low may represent contrarian opportunities or reflect deteriorating fundamentals. Always cross-reference with fundamental metrics rather than relying on price range alone.
Data Sources & Methodology
All financial data displayed on this Biotechnology industry page is sourced from NYSE and NASDAQ company filings, processed through StockSifting's daily data pipeline, and refreshed after each US market close. Fundamental metrics — earnings per share, book value, debt, and revenue — are updated as companies file quarterly reports (10-Q) and annual reports (10-K) with the SEC. Price data reflects the most recent closing price. StockSifting does not provide financial advice. All screening tools are for research and informational purposes only. Conduct your own due diligence before making any investment decision.
Biotechnology Industry Stocks — Frequently Asked Questions
Common questions US investors ask about the Biotechnology industry, answered with data from StockSifting's live screener.
What industry is Biotechnology on the US stock market?
Biotechnology is a recognised industry classification on the US equity market. StockSifting currently tracks 555 NYSE- and NASDAQ-listed companies in the Biotechnology industry, ranging from large-cap S&P 500 constituents to smaller-cap names. The Biotechnology industry page consolidates all these companies into a single sortable view, with live P/E ratio, market cap, ROCE, ROE, dividend yield, and 52-week price range data refreshed daily after US market close.
How many US stocks are in the Biotechnology industry?
StockSifting tracks 555 US-listed companies in the Biotechnology industry across NYSE and NASDAQ. Use the sortable table above to compare them by valuation, profitability, dividend yield, and trading range. Click any company name to open its full profile page with quarterly financials, key ratios, and historical data.
What metrics matter most for Biotechnology industry analysis?
For the Biotechnology industry, the most informative metrics to compare across peers are:
- ROCE — identifies companies with durable competitive advantages generating high returns on invested capital.
- P/E Ratio — measures relative valuation; low P/E within the industry may signal undervaluation.
- ROE — reveals how efficiently management deploys shareholder equity to generate profit.
- Dividend Yield — key for income-oriented US investors screening for reliable cash distributions.
- Market Cap — size and liquidity context; large-caps offer stability, small-caps offer growth potential.
- 52-Week Range — price momentum and volatility signal at a glance.
Comparing these metrics within the Biotechnology industry is more meaningful than cross-sector comparisons, because all companies face similar structural dynamics, cost bases, and regulatory environments.
How do I find the best Biotechnology industry stocks?
There is no single definition of "best" — it depends on your investment objective:
- Quality investors: Sort by ROCE descending to identify the most capital-efficient operators. Look for ROCE above 15% sustained over multiple years, combined with low D/E.
- Value investors: Sort by P/E ascending to find the cheapest earnings. Cross-reference with ROCE to avoid cheap junk — look for low P/E AND high ROCE simultaneously.
- Income investors: Sort by Dividend Yield descending. Verify sustainability by checking payout ratio and free cash flow in individual company profiles.
- Growth investors: Filter by market cap for smaller-cap names with high ROE, indicating efficient growth reinvestment.
Always click through to individual company pages for full due diligence. Nothing on this page constitutes financial advice. Past performance does not guarantee future results.
How often is the Biotechnology industry data updated?
StockSifting refreshes all Biotechnology industry data — price, P/E, market cap, ROCE, ROE, dividend yield, and 52-week range — daily after US market close. Fundamental data (earnings, book value, debt ratios) updates as companies file quarterly 10-Q and annual 10-K reports with the SEC. This means the screener reflects the most current publicly available information for every NYSE- and NASDAQ-listed company in the Biotechnology industry.
555 Companies in the Biotechnology Industry
Compare US-listed Biotechnology industry stocks by price, P/E ratio, market cap, dividend yield, ROCE, ROE, and 52-week high-low range. Click any column header to sort. Click any company name for the full profile.
| #↑ | Company↕ | Price↕ | P/E↕ | Mkt Cap↕ | Div Yield↕ | ROCE↕ | ROE↕ | 52W High↕ | 52W Low↕ |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals Incorporated | $451.63 | 26.79 | $114.63 B | — | — | 0.24% | $507.92 | $362.5 |
| 2 | Regeneron Pharmaceuticals, Inc. | $675.19 | 15.81 | $69.94 B | 0.56% | 10.23% | 14.32% | $821.11 | $541 |
| 3 | Revolution Medicines, Inc. | $183.29 | — | $38.94 B | — | -57.28% | -54.06% | $193.82 | $34 |
| 4 | Alnylam Pharmaceuticals, Inc. | $271.37 | 62.78 | $36.24 B | — | 14.33% | 98.29% | $495.55 | $266.27 |
| 5 | Roivant Sciences Ltd. | $34.96 | — | $33.71 B | — | -21.06% | -6.85% | $37 | $10.9 |
| 6 | Royalty Pharma plc | $58.42 | 40.45 | $33.47 B | 1.61% | 8.21% | 12.67% | $59.44 | $34.08 |
| 7 | Moderna, Inc. | $59.66 | — | $23.63 B | — | -29.7% | -36.73% | $85.6 | $22.28 |
| 8 | Incyte Corporation | $117.39 | 16.47 | $23.57 B | — | 24.67% | 29.2% | $119.6 | $67.17 |
| 9 | Insmed Incorporated | $108.62 | — | $23.23 B | — | -55.4% | -130.11% | $212.75 | $90.39 |
| 10 | BridgeBio Pharma, Inc. | $82.45 | — | $16.09 B | — | -77.47% | -206.74% | $93.42 | $42.09 |
| 11 | Jazz Pharmaceuticals plc | $254.22 | 530.21 | $15.64 B | — | 5.5% | 0.71% | $255.2 | $105 |
| 12 | Ascendis Pharma A/S | $230.83 | 26.29 | $15.14 B | — | — | 3.33% | $250.74 | $160.86 |
| 13 | Exelixis, Inc. | $56.12 | 16.9 | $14.09 B | — | 36.6% | 40.21% | $57.57 | $33.76 |
| 14 | Madrigal Pharmaceuticals, Inc. | $546.79 | — | $12.52 B | — | -31.61% | -50.15% | $615 | $286.44 |
| 15 | Axsome Therapeutics, Inc. | $236.95 | — | $11.76 B | — | -54.42% | -260.01% | $260.19 | $96.09 |
| 16 | BioMarin Pharmaceutical Inc. | $59.21 | 42.58 | $11.44 B | — | 5.99% | 4.41% | $66.28 | $49.26 |
| 17 | Summit Therapeutics Inc. | $14.63 | — | $11.32 B | — | -161.37% | -291.24% | $30.98 | $12.55 |
| 18 | Bio-Techne Corporation | $71.63 | 103.23 | $11.2 B | 0.45% | 10.19% | 5.44% | $72.16 | $43.2 |
| 19 | Arrowhead Pharmaceuticals, Inc. | $74.52 | 53.97 | $10.39 B | — | 8.27% | -55.45% | $87.83 | $14.3 |
| 20 | Corcept Therapeutics Incorporated | $95.65 | 214.5 | $10.16 B | — | 6.68% | 7.42% | $95.79 | $28.66 |
| 21 | Apogee Therapeutics, Inc. | $134.2 | — | $10.11 B | — | -31.41% | -32.64% | $134.32 | $34.34 |
| 22 | Cytokinetics, Incorporated | $81.11 | — | $10.03 B | — | -50.1% | -131.19% | $88.31 | $32.89 |
| 23 | Krystal Biotech, Inc. | $339.06 | 44.45 | $10 B | — | 13.1% | 19.25% | $382.54 | $130.5 |
| 24 | Nuvalent, Inc. | $123.96 | — | $9.79 B | — | -31.35% | -42.78% | $123.99 | $71.13 |
| 25 | Kymera Therapeutics, Inc. | $113.37 | — | $9.3 B | — | -20.82% | -25.02% | $130.05 | $36.65 |
| 26 | Halozyme Therapeutics, Inc. | $78.6 | 26.28 | $9.17 B | — | 34.18% | 126.27% | $82.26 | $55.64 |
| 27 | Spyre Therapeutics, Inc. | $102.7 | — | $8.92 B | — | -30.53% | -31.25% | $105.09 | $14.51 |
| 28 | Praxis Precision Medicines, Inc. | $317.87 | — | $8.9 B | — | -37.15% | -43.02% | $366.52 | $37.19 |
| 29 | Protagonist Therapeutics, Inc. | $138.31 | — | $8.88 B | — | -25.39% | -17.76% | $143.29 | $50.48 |
| 30 | Crinetics Pharmaceuticals, Inc. | $83.9 | — | $8.88 B | — | -49.63% | -43.96% | $84 | $25.83 |
| 31 | Ionis Pharmaceuticals, Inc. | $53.39 | — | $8.82 B | — | -13.92% | -58.65% | $86.74 | $40.03 |
| 32 | ImmunityBio, Inc. | $8.07 | — | $8.43 B | — | -58.17% | -193.29% | $12.43 | $1.95 |
| 33 | Vaxcyte, Inc. | $58.04 | — | $8.36 B | — | -33.02% | -32.51% | $65 | $29.08 |
| 34 | TG Therapeutics, Inc. | $53.95 | 17.88 | $8.26 B | — | 13.56% | 87.36% | $59.3 | $25.28 |
| 35 | Immunovant, Inc. | $39.53 | — | $8.19 B | — | -61.93% | -68.16% | $41.23 | $14.32 |
| 36 | Rhythm Pharmaceuticals, Inc. | $106.6 | — | $7.27 B | — | -51.31% | -86.53% | $122.2 | $74.5 |
| 37 | Mirum Pharmaceuticals, Inc. | $117.05 | — | $7.21 B | — | -3.47% | -289.33% | $130 | $50.25 |
| 38 | Cogent Biosciences, Inc. | $39.64 | — | $6.74 B | — | -38.16% | -83.29% | $43.73 | $10.38 |
| 39 | Arcellx Inc | $0 | — | $6.73 B | — | -50.64% | -55.46% | $115.13 | $60.35 |
| 40 | Erasca, Inc. | $19.38 | — | $6.69 B | — | -35.74% | -77.01% | $24.28 | $1.33 |
| 41 | Xenon Pharmaceuticals Inc. | $66.74 | — | $6.6 B | — | -63.09% | -49.23% | $72.66 | $30 |
| 42 | PTC Therapeutics, Inc. | $78.5 | 875.98 | $6.47 B | — | 44.37% | 0.13% | $90.87 | $43.17 |
| 43 | CG Oncology, Inc. | $71.72 | — | $6.19 B | — | -25.08% | -23.33% | $77 | $23.65 |
| 44 | Terns Pharmaceuticals, Inc. | $0 | — | $6.12 B | — | -10.92% | -20.02% | $53.19 | $5.24 |
| 45 | Scholar Rock Holding Corporation | $50.88 | — | $6.09 B | — | -110.26% | -162.89% | $58.49 | $27.07 |
| 46 | Ligand Pharmaceuticals Incorporated | $305.47 | 38.86 | $5.97 B | — | 3.1% | 16.19% | $326.63 | $129.55 |
| 47 | Definium Therapeutics, Inc. | $45.08 | — | $5.93 B | — | -44.54% | -102.48% | $49.2 | $7.96 |
| 48 | Dianthus Therapeutics, Inc. | $105.72 | — | $5.73 B | — | -35.57% | -27.3% | $107.99 | $18.08 |
| 49 | Oruka Therapeutics, Inc. | $94.32 | — | $5.65 B | — | -25.79% | -25.99% | $97.78 | $12.84 |
| 50 | Travere Therapeutics, Inc. | $56.58 | — | $5.26 B | — | -14.11% | -26.79% | $60.1 | $15.03 |
| 51 | Apellis Pharmaceuticals, Inc. | $0 | 39.41 | $5.25 B | — | 7.37% | 39.71% | $41.14 | $16.83 |
| 52 | Tango Therapeutics, Inc. | $29.02 | — | $4.69 B | — | -29.52% | -41.54% | $34.39 | $5.77 |
| 53 | CRISPR Therapeutics AG | $48.15 | — | $4.65 B | — | -31.41% | -30.88% | $78.48 | $44.12 |
| 54 | Amicus Therapeutics Inc | $0 | — | $4.55 B | — | 4.84% | -12.02% | $14.5 | $5.92 |
| 55 | Caris Life Sciences, Inc. | $15.73 | 130.56 | $4.44 B | — | 4.52% | 6.47% | $42.5 | $14.19 |
| 56 | Veradermics, Incorporated | $109.49 | — | $4.43 B | — | -49.88% | -48.79% | $131.24 | $32 |
| 57 | Celcuity Inc. | $91.69 | — | $4.42 B | — | -40.76% | -244.61% | $151.02 | $13.47 |
| 58 | ACADIA Pharmaceuticals Inc. | $25.43 | 11.47 | $4.31 B | — | 8.14% | 35.65% | $28.35 | $19.69 |
| 59 | Relay Therapeutics, Inc. | $19.3 | — | $4.3 B | — | -50.82% | -43.94% | $20.79 | $3.02 |
| 60 | Edgewise Therapeutics, Inc. | $39.58 | — | $4.28 B | — | -36.44% | -32.55% | $48.4 | $12.3 |
| 61 | NewAmsterdam Pharma Company N.V. | $32.34 | — | $4.27 B | — | -33.02% | -29.8% | $42.2 | $21.14 |
| 62 | Dyne Therapeutics, Inc. | $23.83 | — | $3.94 B | — | -41.2% | -58.28% | $25 | $8.88 |
| 63 | Enliven Therapeutics, Inc. | $54.33 | — | $3.89 B | — | -26.04% | -21.04% | $54.1 | $14.79 |
| 64 | Catalyst Pharmaceuticals, Inc. | $31.49 | 17.42 | $3.85 B | — | 26.94% | 23.65% | $32.56 | $19.05 |
| 65 | Denali Therapeutics Inc. | $23.83 | — | $3.77 B | — | -53.07% | -50.13% | $27.3 | $12.58 |
| 66 | Arcus Biosciences, Inc. | $29.48 | — | $3.68 B | — | -42.51% | -68.97% | $31.73 | $8.84 |
| 67 | Alumis Inc. | $30.05 | — | $3.57 B | — | -134.01% | -54.71% | $31.35 | $3.25 |
| 68 | Arcutis Biotherapeutics, Inc. | $28.26 | — | $3.54 B | — | -4.03% | -1.41% | $31.77 | $13.7 |
| 69 | Viking Therapeutics, Inc. | $30.38 | — | $3.53 B | — | — | -0.7% | $43.15 | $22.96 |
| 70 | IDEAYA Biosciences, Inc. | $35.99 | — | $3.42 B | — | -15.17% | -13.92% | $40.58 | $21.33 |
| 71 | uniQure N.V. | $40.09 | — | $3.08 B | — | -24.65% | -88.99% | $71.5 | $8.73 |
| 72 | MBX Biosciences, Inc. | $60.28 | — | $2.86 B | — | -26.53% | -24.5% | $66.55 | $9.63 |
| 73 | Disc Medicine, Inc. | $75.58 | — | $2.85 B | — | -30.64% | -36.95% | $99.5 | $40 |
| 74 | Celldex Therapeutics, Inc. | $35.66 | — | $2.82 B | — | -54.02% | -50.72% | $40.3 | $19.72 |
| 75 | Ultragenyx Pharmaceutical Inc. | $28.62 | — | $2.81 B | — | -46.6% | -414.17% | $39.89 | $18.29 |
| 76 | Beam Therapeutics Inc. | $27.29 | — | $2.78 B | — | -27.72% | -5.89% | $38.26 | $15.6 |
| 77 | Soleno Therapeutics, Inc. | $0 | 28.77 | $2.76 B | — | 2.98% | 22.86% | $89.12 | $29.43 |
| 78 | Pharvaris N.V. | $34.45 | — | $2.74 B | — | -54.28% | -67.14% | $36.6 | $19.12 |
| 79 | Kodiak Sciences Inc. | $42.42 | — | $2.7 B | — | -76.6% | -253.85% | $47.84 | $5 |
| 80 | Vera Therapeutics, Inc. | $37.17 | — | $2.66 B | — | -46.31% | -74.86% | $56.05 | $19.07 |
| 81 | AtaiBeckley Inc. | $7.13 | — | $2.65 B | — | -76% | -366.49% | $7.22 | $3.06 |
| 82 | Trevi Therapeutics, Inc. | $18.18 | — | $2.59 B | — | -26.85% | -24.53% | $20.22 | $6.55 |
| 83 | Kailera Therapeutics, Inc. | $19.9 | — | $2.58 B | — | — | -0.37% | $28.23 | $18.5 |
| 84 | Immunome, Inc. | $22.78 | — | $2.57 B | — | -35.12% | -51.15% | $27.65 | $8.66 |
| 85 | Nurix Therapeutics, Inc. | $23.48 | — | $2.45 B | — | -47.48% | -76.09% | $25.09 | $8.2 |
| 86 | Tarsus Pharmaceuticals, Inc. | $57.26 | — | $2.44 B | — | -16.64% | -14.19% | $85.25 | $38.51 |
| 87 | SELLAS Life Sciences Group, Inc. | $12.9 | — | $2.42 B | — | -39.64% | -47.12% | $15.88 | $1.39 |
| 88 | Agios Pharmaceuticals, Inc. | $37.36 | — | $2.38 B | — | -38.86% | -34.11% | $46 | $22.24 |
| 89 | Mineralys Therapeutics, Inc. | $27.52 | — | $2.35 B | — | -26.38% | -27.92% | $47.65 | $12.59 |
| 90 | Biohaven Ltd. | $15.51 | — | $2.32 B | — | -222.16% | -450% | $18.57 | $7.48 |
| 91 | Iovance Biotherapeutics, Inc. | $5.48 | — | $2.32 B | — | -51.39% | -50.17% | $5.63 | $1.76 |
| 92 | Nektar Therapeutics | $68.67 | — | $2.24 B | — | -57.64% | -45.78% | $109 | $21.02 |
| 93 | Day One Biopharmaceuticals Inc | $0 | — | $2.22 B | — | -28.56% | -23.43% | $21.53 | $5.63 |
| 94 | Nuvation Bio Inc. | $6.43 | — | $2.19 B | — | -41.57% | -44.1% | $9.75 | $2.18 |
| 95 | Harmony Biosciences Holdings, Inc. | $36.84 | 14.55 | $2.12 B | — | 20.45% | 17.19% | $40.87 | $25.52 |
| 96 | Viridian Therapeutics, Inc. | $19.18 | — | $2.11 B | — | -43.85% | -60.7% | $34.29 | $13.18 |
| 97 | UroGen Pharma Ltd. | $43.78 | — | $2.07 B | — | -81.06% | -204.47% | $43.93 | $15.04 |
| 98 | Sionna Therapeutics, Inc. | $47.21 | — | $2.06 B | — | -28.32% | -27.31% | $51.56 | $16.38 |
| 99 | Damora Therapeutics, Inc. | $32.99 | — | $2.06 B | — | -87.69% | -123.08% | $34.89 | $16.5 |
| 100 | Palvella Therapeutics, Inc. | $143.94 | — | $2.06 B | — | -80.06% | -56.87% | $161.38 | $29.59 |
| 101 | Vericel Corporation | $40.1 | 93.26 | $2.05 B | — | — | 0.07% | $43.57 | $28.95 |
| 102 | ADMA Biologics, Inc. | $8.59 | 12.26 | $2.03 B | — | 34.51% | 38.97% | $20.46 | $7.21 |
| 103 | Monte Rosa Therapeutics, Inc. | $23.63 | — | $2 B | — | -14.1% | -40.99% | $25.77 | $4.12 |
| 104 | Syndax Pharmaceuticals, Inc. | $22.64 | — | $2 B | — | -66.67% | -256.66% | $25.59 | $9.38 |
| 105 | Aurinia Pharmaceuticals Inc. | $15.64 | 6.65 | $1.98 B | — | 16.2% | 64.48% | $19.25 | $8.55 |
| 106 | Precigen, Inc. | $5.49 | — | $1.97 B | — | -90.19% | -642.46% | $6.04 | $1.47 |
| 107 | Ascentage Pharma Group Internat | $19.1 | — | $1.95 B | — | -25.48% | -124.87% | $95.35 | $30 |
| 108 | GH Research PLC | $28.35 | — | $1.93 B | — | -21.68% | -19.83% | $31 | $11.32 |
| 109 | Rapport Therapeutics, Inc. | $42.56 | — | $1.92 B | — | -25.36% | -24.79% | $44.28 | $13.62 |
| 110 | Ocular Therapeutix, Inc. | $8.93 | — | $1.91 B | — | -35.66% | -64.55% | $16.44 | $6.23 |
| 111 | Tyra Biosciences, Inc. | $31.85 | — | $1.88 B | — | -50.19% | -42.66% | $40.65 | $9.96 |
| 112 | Zenas BioPharma, Inc. | $32.36 | — | $1.86 B | — | -65.85% | -167.71% | $44.6 | $13.07 |
| 113 | Maravai LifeSciences Holdings, Inc. | $7.1 | — | $1.84 B | — | -17.71% | -44.72% | $7.3 | $1.99 |
| 114 | Taysha Gene Therapies, Inc. | $5.67 | — | $1.82 B | — | -34.88% | -56.07% | $7.3 | $2.34 |
| 115 | AbCellera Biologics Inc. | $5.97 | — | $1.82 B | — | -15.72% | -14.86% | $8.44 | $2.75 |
| 116 | Sarepta Therapeutics, Inc. | $16.21 | 27.48 | $1.79 B | — | -29.18% | 4.89% | $25.32 | $10.42 |
| 117 | Bicara Therapeutics Inc. | $28.15 | — | $1.78 B | — | -38.7% | -35.89% | $30.99 | $9.57 |
| 118 | Stoke Therapeutics, Inc. | $28.81 | — | $1.78 B | — | -5.71% | -48.84% | $40.22 | $12.25 |
| 119 | Zymeworks Inc. | $24.05 | — | $1.75 B | — | -30.42% | -37.79% | $29.75 | $11.51 |
| 120 | Generate Biomedicines, Inc. | $14.39 | — | $1.74 B | — | -94.79% | -103.72% | $18.18 | $11 |
| 121 | Fortrea Holdings Inc. | $17.91 | — | $1.68 B | — | -1.7% | -79.12% | $18.67 | $4.57 |
| 122 | MoonLake Immunotherapeutics | $20.06 | — | $1.65 B | — | -64.61% | -85.61% | $62.75 | $5.95 |
| 123 | Recursion Pharmaceuticals, Inc. | $3.08 | — | $1.61 B | — | -48.86% | -54.32% | $7.18 | $2.77 |
| 124 | Intellia Therapeutics, Inc. | $11.47 | — | $1.59 B | — | -59.74% | -57.27% | $28.25 | $7.95 |
| 125 | Innoviva, Inc. | $21.58 | 3.15 | $1.59 B | — | 10.33% | 47.59% | $25.15 | $16.52 |
| 126 | Vir Biotechnology, Inc. | $9.42 | — | $1.59 B | — | -52.69% | -49.31% | $11.66 | $4.16 |
| 127 | Maze Therapeutics, Inc. | $29.3 | — | $1.57 B | — | -38.15% | -36.63% | $53.65 | $12.81 |
| 128 | MapLight Therapeutics, Inc. | $37.44 | — | $1.53 B | — | -36.5% | -35.16% | $40.43 | $12.24 |
| 129 | AnaptysBio, Inc. | $53.76 | — | $1.53 B | — | 14.7% | -13.09% | $72.36 | $11.4 |
| 130 | Septerna, Inc. | $33.68 | — | $1.45 B | — | -15.87% | -9.44% | $38.04 | $10.62 |
| 131 | KalVista Pharmaceuticals, Inc. | $27 | — | $1.44 B | — | -89% | -237.53% | $27 | $10.41 |
| 132 | Immatics N.V. | $9.41 | — | $1.43 B | — | -35.05% | -47.09% | $12.41 | $5.05 |
| 133 | Absci Corporation | $8.32 | — | $1.4 B | — | -64.8% | -63.58% | $12.05 | $2.24 |
| 134 | Avalyn Pharma Inc. | $31.45 | — | $1.39 B | — | — | -0.68% | $32.23 | $24.15 |
| 135 | Hemab Therapeutics Holdings, Inc. | $29.24 | — | $1.37 B | — | — | -0.47% | $36.61 | $23 |
| 136 | Aktis Oncology, Inc. | $24.63 | — | $1.32 B | — | -31.96% | -47.53% | $34.19 | $14.72 |
| 137 | ArriVent BioPharma, Inc. | $28.26 | — | $1.31 B | — | -57.79% | -48.98% | $35.83 | $16.1 |
| 138 | Novavax, Inc. | $8.07 | 3.52 | $1.3 B | — | 76.84% | 283.08% | $11.97 | $6.2 |
| 139 | Xencor, Inc. | $20.45 | — | $1.3 B | — | -22.77% | -28.77% | $21.26 | $6.92 |
| 140 | Ardelyx, Inc. | $5.09 | — | $1.26 B | — | -9.92% | -38.11% | $8.4 | $4.08 |
| 141 | Jade Biosciences, Inc. | $20.53 | — | $1.24 B | 0% | -34.07% | -51.34% | $28 | $6.67 |
| 142 | Inhibrx Biosciences, Inc. | $87.61 | — | $1.23 B | — | -119.83% | -269.56% | $155.29 | $20.55 |
| 143 | MannKind Corporation | $4.05 | 144.86 | $1.23 B | — | 7.49% | -297.71% | $6.51 | $2.23 |
| 144 | Savara Inc. | $5.84 | — | $1.22 B | — | -52.68% | -87.19% | $7 | $2.26 |
| 145 | Corvus Pharmaceuticals, Inc. | $14.47 | — | $1.21 B | — | -69.6% | -38.92% | $26.95 | $3.96 |
| 146 | Alpha Tau Medical Ltd. | $13.32 | — | $1.17 B | — | -44.45% | -73.23% | $14.11 | $2.87 |
| 147 | MeiraGTx Holdings plc | $12.52 | — | $1.16 B | — | -86.95% | -315.61% | $15.35 | $6.62 |
| 148 | Capricor Therapeutics, Inc. | $19.79 | — | $1.12 B | — | -33.78% | -59.27% | $40.37 | $4.3 |
| 149 | Wave Life Sciences Ltd. | $5.79 | — | $1.12 B | — | -39.63% | -55.74% | $21.73 | $5.02 |
| 150 | ORIC Pharmaceuticals, Inc. | $10.83 | — | $1.12 B | — | -36.81% | -35.33% | $14.93 | $7.23 |
| 151 | Cullinan Therapeutics, Inc. | $18.06 | — | $1.12 B | — | -58.85% | -51.45% | $19.43 | $5.68 |
| 152 | Vor Biopharma Inc. | $20.05 | — | $1.09 B | — | -84.67% | -142.13% | $53 | $6.5 |
| 153 | EyePoint, Inc. | $13.05 | — | $1.08 B | — | -74.45% | -110.54% | $19.11 | $9.4 |
| 154 | Forte Biosciences, Inc. | $50.73 | — | $1.05 B | — | -113.91% | -106.16% | $52.67 | $9.1 |
| 155 | Lexicon Pharmaceuticals, Inc. | $2.38 | — | $1.02 B | — | -29.8% | -18.64% | $2.68 | $1 |
| 156 | Olema Pharmaceuticals, Inc. | $11.59 | — | $1.02 B | — | -37.1% | -45.95% | $36.26 | $4.37 |
| 157 | Alto Neuroscience, Inc. | $27.07 | — | $1.01 B | — | -38.28% | -47.22% | $28.85 | $2.72 |
| 158 | Avalo Therapeutics, Inc. | $18.82 | — | $987.18 M | — | -70.45% | -77.76% | $24.27 | $6.21 |
| 159 | Janux Therapeutics, Inc. | $16.26 | — | $986.12 M | — | -16.15% | -11.85% | $35.34 | $12.12 |
| 160 | Seaport Therapeutics, Inc. | $18.17 | — | $972.65 M | — | — | -0.28% | $23 | $14.85 |
| 161 | Kura Oncology, Inc. | $10.89 | — | $962.76 M | — | -48.86% | -141.95% | $12.49 | $5.45 |
| 162 | Geron Corporation | $1.44 | — | $936.62 M | — | -11.23% | -27.95% | $2.01 | $1.04 |
| 163 | Replimune Group, Inc. | $11 | — | $921.93 M | — | -53.14% | -128.57% | $13.24 | $1.5 |
| 164 | Odyssey Therapeutics, Inc. | $19.07 | — | $899.61 M | — | — | -0.86% | $20.3 | $15.35 |
| 165 | Phathom Pharmaceuticals, Inc. | $11.25 | — | $887.28 M | — | -125.87% | -232.78% | $18.31 | $7.61 |
| 166 | Annexon, Inc. | $5.39 | — | $887.21 M | — | -92.11% | -101.19% | $7.18 | $2.03 |
| 167 | LB Pharmaceuticals Inc | $32.31 | — | $886.11 M | — | -9.95% | -17.69% | $35.34 | $13.36 |
| 168 | Arbutus Biopharma Corporation | $4.52 | 5.5 | $883.98 M | — | -30.53% | 129.32% | $5.38 | $3.08 |
| 169 | Sana Biotechnology, Inc. | $3.16 | — | $880.79 M | — | -60.83% | -161.87% | $6.55 | $2.61 |
| 170 | Theravance Biopharma, Inc. | $16.84 | 7.61 | $871.23 M | — | -0.81% | 43.85% | $21.03 | $10.82 |
| 171 | Solid Biosciences Inc. | $8.46 | — | $836.33 M | — | -90.02% | -74.45% | $11.45 | $3.79 |
| 172 | Oculis Holding AG | $11.96 | — | $831.84 M | — | -41% | -56.78% | $34.48 | $10.52 |
| 173 | Aclaris Therapeutics, Inc. | $5.69 | — | $785.61 M | — | -53.3% | -55.89% | $5.88 | $1.46 |
| 174 | Zevra Therapeutics, Inc. | $12.45 | 6.29 | $781.26 M | — | -1.72% | 81.34% | $15.04 | $7.16 |
| 175 | Climb Bio, Inc. | $13.1 | — | $753.58 M | — | -42.23% | -31.46% | $14.41 | $1.36 |
| 176 | Design Therapeutics, Inc. | $12.06 | — | $747.61 M | — | -37.28% | -33.07% | $17.25 | $3.76 |
| 177 | Candel Therapeutics, Inc. | $10.22 | — | $745.89 M | — | -41.46% | -60.42% | $11.36 | $4.35 |
| 178 | CytomX Therapeutics, Inc. | $3.42 | — | $740.19 M | — | -21.31% | -36.61% | $8.21 | $1.72 |
| 179 | Rigel Pharmaceuticals, Inc. | $39.31 | 2.01 | $733.79 M | — | 30.28% | 147.03% | $52.24 | $18.8 |
| 180 | Neurogene Inc. | $36.68 | — | $729.32 M | — | -37.96% | -25.27% | $43.66 | $15.93 |
| 181 | Aura Biosciences, Inc. | $7.03 | — | $725.09 M | — | -74.67% | -78.12% | $9.54 | $4.73 |
| 182 | XOMA Royalty Corporation | $40.17 | 21 | $710.16 M | 0.78% | 4.79% | 32.41% | $45.22 | $22.29 |
| 183 | Omeros Corporation | $9.53 | 8.11 | $698.42 M | — | -49.6% | 107.5% | $17.65 | $3.37 |
| 184 | Gyre Therapeutics, Inc. | $6.06 | 119.4 | $684.35 M | — | 7.77% | -6.34% | $9.42 | $5.44 |
| 185 | Immix Biopharma, Inc. | $9.57 | — | $682.71 M | — | -31.62% | -73.23% | $12.14 | $1.94 |
| 186 | BridgeBio Oncology Therapeutics, Inc. | $8.72 | 142.98 | $674.5 M | — | -35.28% | 2.51% | $14.87 | $7 |
| 187 | SpyGlass Pharma, Inc. | $20.27 | — | $669.34 M | — | -38.64% | -75.44% | $32.44 | $17.06 |
| 188 | AgomAb Therapeutics NV | $11.64 | — | $669.09 M | — | -24.35% | -47.78% | $17.82 | $8.75 |
| 189 | Achieve Life Sciences, Inc. | $6.5 | — | $664.72 M | — | -167.79% | -193.49% | $7.11 | $2.37 |
| 190 | Silence Therapeutics plc | $10.85 | — | $663.94 M | — | -76.17% | -103.26% | $2.63 | $1.06 |
| 191 | Shattuck Labs, Inc. | $7.21 | — | $655.2 M | — | -61.34% | -60.73% | $8.33 | $0.71 |
| 192 | MiMedx Group, Inc. | $4.32 | 20.77 | $637.49 M | — | 22.95% | 12.86% | $7.99 | $3.03 |
| 193 | ARS Pharmaceuticals, Inc. | $6.36 | — | $635.54 M | — | -62.2% | -153.61% | $18.63 | $6.42 |
| 194 | Allogene Therapeutics, Inc. | $1.85 | — | $633.36 M | — | -53.97% | -57.07% | $4.46 | $0.98 |
| 195 | Tectonic Therapeutic, Inc. | $32.8 | — | $616.55 M | — | -33.43% | -32.33% | $39.53 | $14.39 |
| 196 | CorMedix Inc. | $8.19 | 3.37 | $610.36 M | — | 23.03% | 50.38% | $14.96 | $6.13 |
| 197 | First Tracks Biotherapeutics, Inc. | $17.42 | — | $607.83 M | — | — | — | $26.8 | $14.72 |
| 198 | Eupraxia Pharmaceuticals Inc. | $6.38 | — | $605.58 M | — | -47.73% | -53.51% | $12.86 | $6.41 |
| 199 | Nuvectis Pharma, Inc. | $19.08 | — | $600.88 M | — | -149.75% | -147.78% | $29.27 | $5.55 |
| 200 | Bright Minds Biosciences Inc. | $60.66 | — | $595.2 M | — | — | -0.15% | $123.75 | $23.18 |
| 201 | 4D Molecular Therapeutics, Inc. | $11.38 | — | $591.24 M | — | -30.52% | -36.83% | $14 | $4.14 |
| 202 | Relmada Therapeutics, Inc. | $5.3 | — | $567.98 M | — | -67.49% | -71.22% | $8 | $0.55 |
| 203 | Zura Bio Limited | $5.68 | — | $559.08 M | — | -74.11% | -54% | $7.44 | $1.34 |
| 204 | Prime Medicine, Inc. | $3.12 | — | $550.88 M | — | -68.25% | -188.82% | $6.94 | $2.67 |
| 205 | Altimmune, Inc. | $2.82 | — | $545.5 M | — | -35.67% | -42.57% | $6.44 | $2.56 |
| 206 | Crescent Biopharma, Inc. | $16.64 | — | $536.78 M | — | -74.74% | -102.11% | $27.41 | $8.72 |
| 207 | REGENXBIO Inc. | $10.34 | — | $536.1 M | — | -48.13% | -232.5% | $16.19 | $5.46 |
| 208 | Arvinas, Inc. | $8.26 | — | $531.68 M | — | -20.59% | -44.38% | $14.51 | $6.06 |
| 209 | Assembly Biosciences, Inc. | $26.47 | — | $522.88 M | — | -5.8% | -4.21% | $39.7 | $16.9 |
| 210 | Eikon Therapeutics, Inc. | $9.91 | — | $522.44 M | — | -62.8% | -114.8% | $17.4 | $7.9 |
| 211 | Ginkgo Bioworks Holdings, Inc. | $7.89 | — | $507.9 M | — | -29.68% | -57.31% | $17.58 | $5.37 |
| 212 | Contineum Therapeutics, Inc. | $13.9 | — | $505.84 M | — | -25.5% | -27.09% | $16.91 | $3.86 |
| 213 | Verastem, Inc. | $6 | — | $505.27 M | — | -97.68% | -163.59% | $11.25 | $3.43 |
| 214 | Rezolute, Inc. | $5.09 | — | $485.79 M | — | -48.84% | -58.82% | $11.46 | $1.07 |
| 215 | ProKidney Corp. | $1.59 | — | $483.3 M | — | -54.13% | -28.1% | $3.55 | $1.52 |
| 216 | Artiva Biotherapeutics, Inc. | $10 | — | $477.14 M | — | -76.21% | -60.22% | $14.53 | $2.22 |
| 217 | Cabaletta Bio, Inc. | $2.82 | — | $454.11 M | — | -149.87% | -131.58% | $4.23 | $1.26 |
| 218 | Prothena Corporation plc | $8.75 | — | $453.9 M | — | -64.54% | -49.88% | $11.8 | $6.24 |
| 219 | Monopar Therapeutics Inc. | $67.47 | — | $451.99 M | — | — | -0.16% | $105 | $29.18 |
| 220 | Editas Medicine, Inc. | $2.89 | — | $442.74 M | — | -70.81% | -677.39% | $4.54 | $1.66 |
| 221 | Puma Biotechnology, Inc. | $8.58 | 18.1 | $441.3 M | — | 27.62% | 20.37% | $8.75 | $3.03 |
| 222 | Kyverna Therapeutics, Inc. | $7.48 | — | $440.16 M | — | -65.99% | -81.87% | $13.67 | $2.8 |
| 223 | Ovid Therapeutics Inc. | $2.41 | — | $439.54 M | — | -29.75% | -22.51% | $3.1 | $0.47 |
| 224 | Ocugen, Inc. | $1.3 | — | $435 M | — | -307.31% | -1306.71% | $2.73 | $0.93 |
| 225 | Sagimet Biosciences Inc. | $7.07 | — | $433.49 M | — | -51.08% | -37.57% | $11.41 | $4.5 |
| 226 | C4 Therapeutics, Inc. | $3.83 | — | $425.68 M | — | -32.05% | -50.68% | $5.17 | $1.69 |
| 227 | Tenax Therapeutics, Inc. | $15.72 | — | $422.02 M | — | -58.09% | -56.32% | $19.4 | $5.77 |
| 228 | Evommune, Inc. | $12.22 | — | $415.29 M | — | -39.16% | -33.5% | $33.2 | $11.15 |
| 229 | Benitec Biopharma Inc. | $11.89 | — | $412.25 M | — | -42.71% | -45.91% | $16.76 | $9.85 |
| 230 | Larimar Therapeutics, Inc. | $3.93 | — | $406.7 M | — | -212.84% | -134.14% | $6.42 | $2.71 |
| 231 | Century Therapeutics, Inc. | $2.24 | — | $398.58 M | — | -5.16% | -53.23% | $3.04 | $0.43 |
| 232 | Atea Pharmaceuticals, Inc. | $4.87 | — | $389.33 M | — | -65.67% | -57.01% | $6.45 | $2.78 |
| 233 | Enanta Pharmaceuticals, Inc. | $13.42 | — | $382.67 M | — | -36.76% | -64.04% | $17.15 | $6.45 |
| 234 | DiaMedica Therapeutics Inc. | $7.08 | — | $382.03 M | — | -61.16% | -77.09% | $10.42 | $3.88 |
| 235 | Upstream Bio, Inc. | $6.98 | — | $379.85 M | — | -47.12% | -43.82% | $33.68 | $5.85 |
| 236 | Sutro Biopharma, Inc. | $23 | — | $379.79 M | — | -106.34% | -223.84% | $43.85 | $7.15 |
| 237 | Compass Therapeutics, Inc. | $2.1 | — | $375.48 M | — | -35.42% | -29.94% | $6.88 | $1.61 |
| 238 | Abeona Therapeutics Inc. | $6.53 | 5.61 | $370.75 M | — | -47.08% | 41.4% | $7.54 | $4 |
| 239 | Rocket Pharmaceuticals, Inc. | $3.4 | — | $367.98 M | — | -76.11% | -70.79% | $5.45 | $2.53 |
| 240 | Zentalis Pharmaceuticals, Inc. | $5.01 | — | $363.76 M | — | -57.45% | -52.77% | $6.95 | $1.21 |
| 241 | Fennec Pharmaceuticals Inc. | $10.39 | — | $363 M | — | -10.57% | -12.54% | $11.31 | $5.65 |
| 242 | Q32 Bio Inc. | $15.41 | 12.17 | $362.8 M | — | 33.52% | 137.41% | $23.57 | $1.57 |
| 243 | X4 Pharmaceuticals, Inc. | $3.69 | — | $361.28 M | — | -32.82% | -94.9% | $4.83 | $1.35 |
| 244 | Lexeo Therapeutics, Inc. | $4.66 | — | $357.27 M | — | -85.23% | -47.48% | $10.99 | $3.6 |
| 245 | Conexeu Sciences Inc. | $13.28 | — | $355.35 M | — | — | — | $18.79 | $9.6 |
| 246 | Palisade Bio, Inc. | $1.92 | — | $334.14 M | — | -13.92% | -36.79% | $2.85 | $0.53 |
| 247 | Fate Therapeutics, Inc. | $2.83 | — | $325.78 M | — | -52.22% | -58.89% | $3.23 | $0.91 |
| 248 | Vanda Pharmaceuticals Inc. | $5.48 | — | $325.63 M | — | -43.97% | -61.41% | $9.94 | $4.14 |
| 249 | Prelude Therapeutics Incorporated | $4.04 | — | $321.77 M | — | -118.39% | -74.57% | $5.69 | $0.75 |
| 250 | Lyell Immunopharma, Inc. | $13.11 | — | $315.98 M | — | -69.37% | -85.71% | $45 | $9.24 |
| 251 | InflaRx N.V. | $1.81 | — | $307.35 M | — | -114.26% | -69.5% | $2.95 | $0.74 |
| 252 | Eledon Pharmaceuticals, Inc. | $3.95 | — | $304.13 M | — | -55.26% | -71.97% | $4.6 | $1.35 |
| 253 | Neumora Therapeutics, Inc. | $1.61 | — | $302.01 M | — | -152.06% | -181.7% | $3.65 | $0.83 |
| 254 | Foghorn Therapeutics Inc. | $5.16 | — | $301.79 M | — | -59.34% | -301.61% | $6.95 | $3.27 |
| 255 | OmniAb, Inc. | $2.09 | — | $301.54 M | — | -24.23% | -20.31% | $2.79 | $1.3 |
| 256 | Turn Therapeutics Inc. | $10.18 | — | $299.37 M | — | -134.02% | -117.3% | $26.5 | $2.57 |
| 257 | Inhibikase Therapeutics, Inc. | $2.23 | — | $295.09 M | — | -30.85% | -57.15% | $2.36 | $1.33 |
| 258 | Sol-Gel Technologies Ltd. | $89.74 | — | $292.18 M | — | -31.74% | -3.17% | $97.97 | $8.03 |
| 259 | Indaptus Therapeutics, Inc. | $2.52 | — | $288.77 M | — | -629.32% | -454.03% | $12.03 | $0.92 |
| 260 | Immuneering Corporation | $4.46 | — | $287.58 M | — | -26.76% | -31.93% | $10.08 | $2.9 |
| 261 | AC Immune SA | $2.3 | — | $286.39 M | — | -115.62% | -124.01% | $4 | $2.02 |
| 262 | Lineage Cell Therapeutics, Inc. | $1.14 | — | $281.71 M | — | -21.52% | -151.35% | $2.09 | $0.93 |
| 263 | ALX Oncology Holdings Inc. | $2.05 | — | $277.2 M | — | -292.37% | -124.06% | $2.66 | $0.44 |
| 264 | ProQR Therapeutics N.V. | $1.88 | — | $277.12 M | — | -54.09% | -86.22% | $3.1 | $1.33 |
| 265 | MacroGenics, Inc. | $4.54 | — | $274.59 M | — | -34.08% | -147.8% | $5.08 | $1.29 |
| 266 | Niagen Bioscience, Inc. | $3.49 | 14.51 | $270.39 M | — | 16.53% | 25.38% | $11.29 | $3.17 |
| 267 | SAB Biotherapeutics, Inc. | $3.64 | 20.22 | $268.39 M | — | -30.19% | 15.17% | $6.6 | $1.85 |
| 268 | Surrozen, Inc. | $22.99 | — | $266.92 M | — | -47.4% | 58.23% | $35 | $8.2 |
| 269 | Galectin Therapeutics Inc. | $3.85 | — | $263.43 M | — | -174.62% | -258.62% | $7.13 | $2.02 |
| 270 | Satellos Bioscience Inc. | $8.53 | — | $256.02 M | — | -95.23% | -66.75% | $18.98 | $6.36 |
| 271 | Opus Genetics, Inc. | $3.06 | — | $255.54 M | — | -90.9% | -316.35% | $5.81 | $1.04 |
| 272 | Entrada Therapeutics, Inc. | $6.46 | — | $250.2 M | — | -44.74% | -51.22% | $16.45 | $4.93 |
| 273 | Fulcrum Therapeutics, Inc. | $3.68 | — | $246.21 M | — | -24% | -22.54% | $15.74 | $2.83 |
| 274 | Cartesian Therapeutics, Inc. | $8.13 | — | $238.58 M | — | -30.8% | -3215.82% | $14.56 | $5.6 |
| 275 | Anavex Life Sciences Corp. | $2.56 | — | $236.31 M | — | -54.15% | -38.76% | $13.99 | $2.25 |
| 276 | Protara Therapeutics, Inc. | $4.09 | — | $229.59 M | — | -32.51% | -38.7% | $7.82 | $2.97 |
| 277 | Outlook Therapeutics, Inc. | $1.42 | — | $225.81 M | — | 246.27% | -415.51% | $3.39 | $0.16 |
| 278 | Compugen Ltd. | $2.49 | 6.39 | $222.67 M | — | 23.38% | 47.72% | $3.23 | $1.29 |
| 279 | Orchestra BioMed Holdings, Inc. | $3.69 | — | $222.16 M | — | -52.8% | -137.82% | $5.42 | $2.2 |
| 280 | Coherus Oncology, Inc. | $1.47 | 1.18 | $219.03 M | — | -155.52% | 214.57% | $2.62 | $0.81 |
| 281 | Nautilus Biotechnology, Inc. | $1.7 | — | $217.94 M | — | -36.49% | -35.04% | $4.31 | $0.62 |
| 282 | Greenwich LifeSciences, Inc. | $14.65 | — | $217.24 M | — | -631.87% | -941.06% | $34.1 | $7.78 |
| 283 | Agenus Inc. | $5.58 | 3.27 | $211.13 M | — | 21.26% | 76.63% | $8.7 | $2.71 |
| 284 | Whitehawk Therapeutics, Inc. | $3.91 | — | $209.22 M | — | -83.93% | -79.63% | $5.5 | $1.57 |
| 285 | Keros Therapeutics, Inc. | $10.57 | 2.55 | $207.72 M | — | 21.27% | -17.04% | $22.55 | $9.69 |
| 286 | Immunic, Inc. | $15.15 | — | $204.8 M | — | 1572.16% | -130.32% | $15.84 | $5.06 |
| 287 | Minerva Neurosciences, Inc. | $4.48 | — | $203.59 M | — | -15.79% | -169.62% | $12.46 | $1.76 |
| 288 | Atrium Therapeutics, Inc. | $12.29 | — | $201.16 M | — | -32.47% | -40.3% | $73.06 | $11.4 |
| 289 | Codexis, Inc. | $2.2 | — | $200.88 M | — | -31.3% | -68.09% | $3.87 | $0.96 |
| 290 | Invivyd, Inc. | $0.68 | — | $199.95 M | — | -22.89% | -53.48% | $3.07 | $0.48 |
| 291 | Precision BioSciences, Inc. | $7.62 | — | $197.13 M | — | -35.84% | -79.62% | $9.62 | $3.53 |
| 292 | Protalix BioTherapeutics, Inc. | $2.36 | 12.53 | $192.16 M | — | -9.85% | 28.1% | $3.19 | $1.41 |
| 293 | Armata Pharmaceuticals, Inc. | $5.16 | — | $188.69 M | — | -45.96% | -120% | $16.34 | $2.32 |
| 294 | MediWound Ltd. | $14.28 | — | $187.55 M | — | -41.75% | -67.22% | $21.11 | $13.54 |
| 295 | Voyager Therapeutics, Inc. | $3.14 | — | $186.7 M | — | -58.41% | -55.97% | $5.55 | $2.88 |
| 296 | Nkarta, Inc. | $2.58 | — | $183.51 M | — | -31.94% | -30.9% | $3.72 | $1.7 |
| 297 | NRx Pharmaceuticals, Inc. | $4.46 | — | $183.29 M | — | 103.85% | -195.76% | $5.05 | $1.62 |
| 298 | Humacyte, Inc. | $0.67 | — | $180.79 M | — | -110.35% | -1278.91% | $2.84 | $0.55 |
| 299 | AN2 Therapeutics, Inc. | $5 | — | $180.08 M | — | -71.59% | -52.35% | $6.91 | $1 |
| 300 | Tenaya Therapeutics, Inc. | $0.82 | — | $177.34 M | — | -70.98% | -80.56% | $2.35 | $0.53 |
| 301 | Alpha Cognition Inc. Common Stock | $7.89 | — | $177.02 M | — | -23.03% | -54.13% | $10.34 | $4.5 |
| 302 | Tonix Pharmaceuticals Holding Corp. | $11.56 | — | $175.03 M | — | -49.81% | -67.65% | $69.97 | $10.03 |
| 303 | Tiziana Life Sciences Ltd | $1 | — | $173.48 M | — | -401.27% | -195.51% | $2.6 | $0.91 |
| 304 | CAMP4 THERAPEUTICS CORPORATION | $3.19 | — | $172.39 M | — | -50.89% | -194.74% | $7.75 | $1.32 |
| 305 | Korro Bio, Inc. | $11.96 | — | $170.69 M | — | -85.99% | -117.86% | $55.89 | $5.2 |
| 306 | Arcturus Therapeutics Holdings Inc. | $5.99 | — | $169.69 M | — | -32.48% | -36.55% | $24.17 | $5.77 |
| 307 | Karyopharm Therapeutics Inc. | $7.87 | — | $169.29 M | — | -554.58% | -182.43% | $10.99 | $3.65 |
| 308 | OnKure Therapeutics, Inc. | $4.17 | — | $168.45 M | — | -112.02% | -61.02% | $5.38 | $1.91 |
| 309 | Alector, Inc. | $1.54 | — | $168.2 M | — | -69.73% | -295.17% | $3.4 | $1.09 |
| 310 | Oramed Pharmaceuticals Inc. | $4.02 | 1.53 | $167.8 M | — | -7.12% | 55.11% | $5.19 | $1.98 |
| 311 | Corbus Pharmaceuticals Holdings, Inc. | $8.98 | — | $166.01 M | — | -57.84% | -70.89% | $20.56 | $7.12 |
| 312 | Equillium, Inc. | $2.63 | — | $165.65 M | — | -81.63% | -61.43% | $3.54 | $0.36 |
| 313 | Caribou Biosciences, Inc. | $1.65 | — | $163.65 M | — | -90.82% | -100.13% | $3.54 | $1.38 |
| 314 | Canton Strategic Holdings, Inc. | $2.16 | — | $163.11 M | — | -3.9% | -36.93% | $9.08 | $1.08 |
| 315 | ADC Therapeutics SA | $1.27 | — | $161.53 M | — | -42.38% | -229.23% | $4.98 | $0.78 |
| 316 | Acumen Pharmaceuticals, Inc. | $2.23 | — | $160.71 M | — | -133.4% | -123.07% | $3.6 | $1.19 |
| 317 | LENZ Therapeutics, Inc. | $5.16 | — | $158.34 M | — | -32.01% | -37.56% | $50.4 | $4.68 |
| 318 | Unicycive Therapeutics, Inc. | $5.69 | — | $152.19 M | — | -97.75% | -131.18% | $8.74 | $3.71 |
| 319 | Milestone Pharmaceuticals Inc. | $1.23 | — | $150.64 M | — | -62.4% | -169.03% | $3.06 | $1 |
| 320 | PepGen Inc. | $2.12 | — | $149.06 M | — | -58.05% | -59.89% | $7.8 | $1.01 |
| 321 | Oncolytics Biotech Inc. | $0.86 | — | $142.79 M | — | -1939.57% | -440.39% | $1.85 | $1.13 |
| 322 | TuHURA Biosciences, Inc. | $2.21 | — | $141.69 M | 0.01% | -120.19% | -153.95% | $3.9 | $0.41 |
| 323 | Pyxis Oncology, Inc. | $2.23 | — | $141.6 M | — | -119.93% | -70.8% | $5.55 | $0.97 |
| 324 | Cibus, Inc. | $1.86 | — | $141.21 M | — | -23.41% | -225.59% | $4.19 | $1.09 |
| 325 | Cue Biopharma, Inc. | $33.46 | — | $140.42 M | — | -92.35% | -98.3% | $45.5 | $4.97 |
| 326 | Connect Biopharma Holdings Limited | $2.21 | — | $139.46 M | — | -24.19% | -122.29% | $3.82 | $1.23 |
| 327 | NervGen Pharma Corp. | $1.78 | — | $136.48 M | — | -721.31% | -399.62% | $8.49 | $2.71 |
| 328 | Genelux Corporation | $2.89 | — | $131.38 M | — | -259.44% | -174.55% | $8.54 | $2.29 |
| 329 | vTv Therapeutics Inc. | $32.91 | 57.32 | $129.08 M | — | -39.41% | 3.96% | $44 | $14 |
| 330 | enGene Therapeutics Inc. | $1.93 | — | $127.61 M | — | -65% | -56.06% | $12.25 | $1.4 |
| 331 | ProMIS Neurosciences, Inc. | $14.49 | — | $125.95 M | — | 3267.2% | -56.72% | $39.75 | $6.27 |
| 332 | Vivani Medical, Inc. | $1.43 | — | $125.9 M | — | -84.04% | -264.04% | $1.92 | $0.92 |
| 333 | Lixte Biotechnology Holdings, Inc. | $5.41 | — | $125.36 M | — | -431.9% | -124.69% | $8.38 | $2.36 |
| 334 | Spruce Biosciences, Inc. | $45.68 | — | $125.28 M | — | -85.04% | -155.4% | $240 | $6.76 |
| 335 | Fractyl Health, Inc. | $0.77 | — | $123.87 M | — | -93.93% | -852.14% | $2.44 | $0.38 |
| 336 | Anixa Biosciences, Inc. | $3.56 | — | $121.12 M | — | -82.91% | -65.47% | $5.46 | $2.32 |
| 337 | Aardvark Therapeutics, Inc. | $6.08 | — | $121.02 M | — | -58.82% | -61.71% | $17.94 | $3.35 |
| 338 | Polaryx Therapeutics, Inc. | $2.32 | — | $117.64 M | — | -171.33% | -644.23% | $48.91 | $2.01 |
| 339 | Seer, Inc. | $2.1 | — | $115.33 M | — | -27.82% | -26.58% | $2.41 | $1.55 |
| 340 | Black Diamond Therapeutics, Inc. | $1.87 | 7.22 | $106.87 M | — | 15.61% | -36.37% | $4.94 | $1.6 |
| 341 | Coya Therapeutics, Inc. | $4.55 | — | $104.15 M | — | -51.17% | -57.26% | $7.75 | $3.71 |
| 342 | Aldeyra Therapeutics, Inc. | $1.75 | — | $102.55 M | — | -79.69% | -57.34% | $6.17 | $1.07 |
| 343 | Coeptis Therapeutics Holdings Inc | $4.53 | — | $102.06 M | — | -90.67% | -641.09% | $21.41 | $4.35 |
| 344 | ImmuCell Corporation | $11.2 | — | $101.06 M | — | 4.28% | -1.88% | $12.1 | $4.52 |
| 345 | OKYO Pharma Limited | $1.44 | — | $99.71 M | — | 127.79% | -134.46% | $3.35 | $1.34 |
| 346 | Fortress Biotech, Inc. | $2.99 | 0.93 | $99.33 M | — | — | 1.1% | $4.53 | $1.7 |
| 347 | Entera Bio Ltd. | $1.96 | — | $98.09 M | — | -83.6% | -87.97% | $3.22 | $0.91 |
| 348 | Biomea Fusion, Inc. | $1.33 | — | $95.8 M | — | -171.28% | -196.72% | $2.99 | $0.87 |
| 349 | Rani Therapeutics Holdings, Inc. | $0.69 | — | $94.88 M | — | -83.37% | -56.46% | $3.87 | $0.4 |
| 350 | Pelthos Therapeutics Inc. | $26.86 | — | $94.75 M | — | -31.06% | -2.4% | $37.5 | $16.5 |
| 351 | Verrica Pharmaceuticals Inc. | $5.44 | — | $93.62 M | — | -38.9% | -87.04% | $9.82 | $3.28 |
| 352 | Heron Therapeutics, Inc. | $0.48 | — | $90.93 M | — | -1.59% | -223.39% | $1.99 | $0.38 |
| 353 | Inovio Pharmaceuticals, Inc. | $1.1 | — | $88.44 M | — | -283.35% | -201.57% | $2.98 | $1.03 |
| 354 | Rallybio Corporation | $16.91 | — | $88.27 M | — | -56.97% | -14.39% | $17.57 | $3.2 |
| 355 | Cognition Therapeutics, Inc. | $1 | — | $87.39 M | — | -70.77% | -72.68% | $3.83 | $0.55 |
| 356 | Kalaris Therapeutics, Inc. | $4.04 | — | $86.44 M | — | -41.2% | -72.78% | $11.88 | $2.14 |
| 357 | NeurAxis, Inc. | $7.01 | — | $84.96 M | — | -216.78% | -185.74% | $9.33 | $2.2 |
| 358 | NeOnc Technologies Holdings, Inc. | $3.37 | — | $84.8 M | — | 129% | 122.08% | $12.99 | $3 |
| 359 | Champions Oncology, Inc. | $6.1 | — | $84.71 M | — | 57.07% | -58.02% | $8.74 | $5.5 |
| 360 | Spero Therapeutics, Inc. | $1.38 | 5.23 | $79.61 M | — | 11.92% | 35.58% | $3.08 | $1.37 |
| 361 | Rein Therapeutics Inc. | $0.89 | — | $77.91 M | — | -121.99% | -163.66% | $2.18 | $0.83 |
| 362 | Gain Therapeutics, Inc. | $1.84 | — | $77.84 M | — | -96.12% | -201.43% | $4.34 | $1.41 |
| 363 | MAIA Biotechnology, Inc. | $1.33 | — | $77.82 M | — | -618.06% | -284.8% | $3.19 | $0.87 |
| 364 | Enlivex Ltd. | $4.73 | 0.06 | $76.75 M | — | -0.65% | 248.08% | $31.5 | $4.25 |
| 365 | Adicet Bio, Inc. | $8.12 | — | $75.53 M | — | -71.49% | -80.35% | $17.44 | $6.01 |
| 366 | LeonaBio, Inc. | $7.98 | — | $74.87 M | — | -76.55% | -381.01% | $14.21 | $3.24 |
| 367 | Atara Biotherapeutics, Inc. | $8.63 | 2.5 | $74.69 M | — | 674.99% | -315.42% | $19.14 | $3.92 |
| 368 | Acrivon Therapeutics, Inc. | $1.75 | — | $74.48 M | — | -73.75% | -64.43% | $3.56 | $1.2 |
| 369 | Annovis Bio, Inc. | $1.75 | — | $74.45 M | — | — | -2.21% | $5.5 | $1.54 |
| 370 | Gossamer Bio, Inc. | $0.15 | — | $73.96 M | — | -150.03% | -118.77% | $3.87 | $0.11 |
| 371 | PolyPid Ltd. | $3.74 | — | $73.85 M | — | -226.3% | -241.96% | $5.73 | $3.06 |
| 372 | Elicio Therapeutics, Inc. | $3.08 | — | $72.98 M | — | -210.11% | -977.67% | $16 | $2.66 |
| 373 | ImageneBio, Inc. | $6 | — | $70.03 M | — | -34.18% | -35.2% | $18 | $3.94 |
| 374 | PMV Pharmaceuticals, Inc. | $1.31 | — | $69.33 M | — | -81.99% | -68.98% | $1.88 | $1.02 |
| 375 | XBiotech Inc. | $2.24 | — | $69.21 M | — | -39.17% | -26.1% | $3.61 | $2.09 |
| 376 | iBio, Inc. | $1.41 | — | $68.06 M | — | -108.92% | -53.86% | $3.82 | $0.56 |
| 377 | OS Therapies Incorporated | $1.56 | — | $67.25 M | — | 582.87% | -567.59% | $2.57 | $1.15 |
| 378 | Pliant Therapeutics, Inc. | $1.09 | — | $67.18 M | — | -74.87% | -69.56% | $1.95 | $1.07 |
| 379 | MediciNova, Inc. | $1.33 | — | $65.46 M | — | -31.77% | -27.26% | $1.96 | $1.17 |
| 380 | Telomir Pharmaceuticals, Inc. | $1.08 | — | $63.22 M | — | -178.22% | -201.23% | $3.1 | $0.89 |
| 381 | Cingulate Inc. | $4.78 | — | $63.17 M | — | -418.81% | -365.16% | $11.89 | $3.16 |
| 382 | TScan Therapeutics, Inc. | $0.94 | — | $61.5 M | — | -64.64% | -91.94% | $2.57 | $0.83 |
| 383 | Edesa Biotech, Inc. | $6.03 | — | $57.65 M | — | -57.24% | -82.34% | $20.32 | $0.72 |
| 384 | Context Therapeutics Inc. | $0.63 | — | $57.53 M | — | -65.65% | -59.95% | $3.62 | $0.55 |
| 385 | Cardiff Oncology, Inc. | $0.84 | — | $57.16 M | — | -107.63% | -95.5% | $4.52 | $0.82 |
| 386 | MiNK Therapeutics, Inc. | $11.07 | — | $54.95 M | — | 859.68% | -168.87% | $22.34 | $8.48 |
| 387 | Boundless Bio, Inc. | $2.48 | — | $54.84 M | — | -43.97% | -53.6% | $2.79 | $0.96 |
| 388 | Xilio Therapeutics, Inc. | $8.7 | — | $53.93 M | — | -42.66% | -39.2% | $12.74 | $6.47 |
| 389 | Dyadic International, Inc. | $1.47 | — | $53.93 M | — | -114.18% | -350.86% | $1.35 | $0.65 |
| 390 | Kezar Life Sciences, Inc. | $0 | — | $53.86 M | — | -74.59% | -64.42% | $7.55 | $3.53 |
| 391 | Dogwood Therapeutics, Inc. | $1.55 | 1.32 | $52.13 M | — | — | -0.35% | $9.5 | $1.28 |
| 392 | eXoZymes, Inc. | $5.33 | — | $51.98 M | — | -220.6% | -220.64% | $18.4 | $5.25 |
| 393 | INmune Bio Inc. | $1.97 | — | $51.97 M | — | -128.97% | -170.86% | $3.24 | $1.09 |
| 394 | NovaBay Pharmaceuticals Inc | $1.2 | — | $51.92 M | 0% | -96.1% | -109.37% | $99.75 | $1 |
| 395 | BeyondSpring Inc. | $1.25 | — | $51.61 M | — | -72.39% | -133.13% | $2.44 | $1.16 |
| 396 | Seres Therapeutics, Inc. | $5.25 | 12.68 | $50.07 M | — | -79.05% | -127.3% | $29.98 | $5 |
| 397 | Instil Bio, Inc. | $7.25 | — | $49.17 M | — | -26.15% | -39.76% | $33.83 | $5.67 |
| 398 | Filana Therapeutics, Inc. | $1.01 | — | $49.03 M | — | -128.99% | -99.85% | $2.27 | $1 |
| 399 | MindWalk Holdings Corp. | $1.46 | — | $48.7 M | — | -34.42% | -63.66% | $3.25 | $0.99 |
| 400 | Impact BioMedical Inc. | $0.44 | — | $47.98 M | — | -26.29% | 24.58% | $0.83 | $0.37 |
| 401 | aTyr Pharma, Inc. | $0.49 | — | $47.85 M | — | -99.71% | -99.62% | $7.29 | $0.4 |
| 402 | Metagenomi Therapeutics, Inc. | $1.22 | — | $45.93 M | — | -48.45% | -51.23% | $3.95 | $1.13 |
| 403 | PDS Biotechnology Corporation | $0.76 | — | $42.66 M | — | -150.13% | -346.03% | $1.55 | $0.51 |
| 404 | Hyperion DeFi, Inc. | $2.76 | — | $41.99 M | — | -38.69% | -42.8% | $15 | $2.49 |
| 405 | NanoViricides, Inc. | $1.6 | — | $40.22 M | — | -127.59% | -92.69% | $2.23 | $0.85 |
| 406 | Tevogen Bio Holdings Inc. | $9.46 | — | $39.91 M | — | — | — | $71 | $4.13 |
| 407 | Grace Therapeutics, Inc. | $2.43 | — | $39.71 M | — | -23.81% | -6.94% | $5.18 | $1.79 |
| 408 | Apollomics, Inc. | $18.71 | — | $39.22 M | — | -737.55% | -693.39% | $42.12 | $3.66 |
| 409 | RenovoRx, Inc. | $0.88 | — | $39.2 M | — | -176.68% | -138.61% | $1.45 | $0.7 |
| 410 | CervoMed Inc. | $2.89 | — | $38.89 M | — | -155.27% | -136.08% | $13.13 | $2.13 |
| 411 | VYNE Therapeutics Inc. | $0.89 | — | $38.26 M | — | -107.15% | -69.57% | $1.59 | $0.28 |
| 412 | Lantern Pharma Inc. | $2.94 | — | $37.89 M | — | -275.14% | -198.35% | $5.74 | $1.11 |
| 413 | Veru Inc. | $2.34 | — | $36.92 M | — | -161.13% | -52.86% | $7.33 | $2.05 |
| 414 | Nutriband Inc. | $3.08 | — | $36.71 M | — | -103.12% | -112.6% | $9.21 | $2.9 |
| 415 | Lite Strategy, Inc. | $1 | — | $35.9 M | 0% | -103.09% | -68.86% | $8.25 | $0.69 |
| 416 | Estrella Immunopharma, Inc. | $0.8 | — | $35.07 M | — | 126.01% | -259.11% | $3.15 | $0.73 |
| 417 | Aligos Therapeutics, Inc. | $5.44 | — | $33.57 M | — | -130.74% | -139.47% | $13.69 | $4.8 |
| 418 | Actuate Therapeutics, Inc. Common stock | $1.35 | — | $33.5 M | — | -270.08% | -206.5% | $9.22 | $1.16 |
| 419 | ABVC BioPharma, Inc. | $1.23 | — | $32.24 M | — | -48% | -92.02% | $3.6 | $0.88 |
| 420 | Serina Therapeutics, Inc. | $2.09 | — | $31.12 M | — | -709.03% | -903.25% | $7.92 | $1.22 |
| 421 | Hoth Therapeutics, Inc. | $0.84 | — | $30.69 M | — | -200.97% | -165.25% | $2.45 | $0.49 |
| 422 | Quantum BioPharma Ltd. | $3.02 | — | $28.79 M | — | -300.19% | -625.19% | $43 | $2.85 |
| 423 | Kyntra Bio, Inc. | $7.3 | 0.17 | $28.5 M | — | -50.18% | -290.91% | $12.6 | $6.32 |
| 424 | Actinium Pharmaceuticals, Inc. | $0.9 | — | $27.7 M | — | -82.74% | -218.67% | $1.89 | $0.88 |
| 425 | Polyrizon Ltd. | $13.49 | — | $27.63 M | — | -27.56% | -17.84% | $18.2 | $2.88 |
| 426 | Tvardi Therapeutics, Inc. | $2.86 | — | $27.49 M | — | -127.18% | -64.17% | $43.65 | $1.5 |
| 427 | Plus Therapeutics, Inc. | $3.92 | — | $27.12 M | — | -381.4% | -198.48% | $23.43 | $2.9 |
| 428 | IGC Pharma, Inc. | $0.27 | — | $26.99 M | — | -114.73% | -94.51% | $0.5 | $0.24 |
| 429 | Evaxion A/S | $3.02 | — | $25.65 M | — | -38.23% | -111.18% | $12.15 | $2.45 |
| 430 | BriaCell Therapeutics Corp. | $2.9 | — | $25.23 M | — | — | -1.75% | $31.6 | $2.6 |
| 431 | NeuroSense Therapeutics Ltd. | $0.7 | — | $24.39 M | — | -383.35% | -395.28% | $2.1 | $0.63 |
| 432 | Atossa Therapeutics, Inc. | $2.4 | — | $24.34 M | — | -94.38% | -84.91% | $19.35 | $1.7 |
| 433 | Celularity Inc. | $0.81 | — | $23.74 M | — | -48.8% | -272.44% | $4.35 | $0.56 |
| 434 | Neuphoria Therapeutics Inc. | $4.31 | — | $23.29 M | — | — | -0.63% | $21.4 | $3.65 |
| 435 | GridAI Technologies Corp. | $3.54 | — | $23.26 M | — | -27% | -18.69% | $6.93 | $1.08 |
| 436 | Skye Bioscience, Inc. | $0.64 | — | $22.49 M | — | -289.25% | -217.27% | $4.99 | $0.57 |
| 437 | CEL-SCI Corporation | $1.25 | — | $22.46 M | — | -107.75% | -221.5% | $13.48 | $0.89 |
| 438 | Jasper Therapeutics, Inc. | $0.77 | — | $22.21 M | — | -371.51% | -523.04% | $3.48 | $0.32 |
| 439 | CalciMedica, Inc. | $0.71 | — | $21.83 M | — | -235.71% | -206.51% | $7.2 | $0.46 |
| 440 | Marker Therapeutics, Inc. | $1.27 | — | $21.51 M | — | -74.05% | -80.86% | $2.46 | $0.81 |
| 441 | NewcelX Ltd. | $3.81 | — | $20.79 M | — | 23.66% | -100.99% | $28.03 | $1.83 |
| 442 | NextCure, Inc. | $5.11 | — | $20.79 M | — | -145.43% | -186.96% | $15.74 | $1.55 |
| 443 | Pluri Inc. | $1.95 | — | $20.61 M | — | -348.95% | -53.15% | $5.68 | $1.56 |
| 444 | Cellectar Biosciences, Inc. | $2.58 | — | $20.14 M | — | -224.66% | -264.79% | $6.52 | $2.2 |
| 445 | Lisata Therapeutics, Inc. | $2.24 | — | $19.85 M | — | -124.1% | -84.39% | $5.07 | $1.81 |
| 446 | Sensei Biotherapeutics, Inc. | $28.37 | — | $19.5 M | — | -119.5% | -283.67% | $37.9 | $6.33 |
| 447 | Allarity Therapeutics, Inc. | $1.22 | — | $19.41 M | — | -148.49% | -109.94% | $2.35 | $0.77 |
| 448 | Longeveron Inc. | $0.61 | — | $19.34 M | — | -377.18% | -202.41% | $1.8 | $0.47 |
| 449 | Daré Bioscience, Inc. | $1.25 | — | $18.88 M | — | -154.2% | -373.17% | $3.78 | $1.23 |
| 450 | Quince Therapeutics, Inc. | $18.78 | — | $18.38 M | — | -33.74% | 67.67% | $910 | $15.1 |
| 451 | Lipocine Inc. | $2.19 | — | $17.73 M | — | -71.64% | -66.69% | $12.37 | $1.81 |
| 452 | Werewolf Therapeutics, Inc. | $0.36 | — | $17.6 M | — | -182.5% | -208.23% | $2.38 | $0.27 |
| 453 | Cyclerion Therapeutics, Inc. | $3.69 | — | $16.09 M | — | -40.99% | -62.1% | $8.48 | $1.03 |
| 454 | Tempest Therapeutics, Inc. | $0.99 | — | $15.98 M | — | -195.16% | -729.89% | $12.23 | $0.93 |
| 455 | GT Biopharma, Inc. | $0.36 | — | $15.88 M | — | -214.65% | -321.96% | $2.29 | $0.26 |
| 456 | Passage Bio, Inc. | $4.91 | — | $15.58 M | — | -110.08% | -150.88% | $20 | $3.29 |
| 457 | Pasithea Therapeutics Corp. | $0.45 | — | $15.39 M | — | -37.74% | -57.44% | $2.06 | $0.28 |
| 458 | SeaStar Medical Holding Corporation | $3.86 | — | $15.39 M | — | -116.89% | -146.29% | $12.5 | $2.07 |
| 459 | OSR Holdings, Inc. | $0.44 | — | $15.36 M | — | 79.82% | -11% | $1.24 | $0.3 |
| 460 | Vyome Holdings, Inc. | $2.18 | — | $15.16 M | — | -73.02% | -302.13% | $18.6 | $1.75 |
| 461 | Citius Pharmaceuticals, Inc. | $0.55 | — | $15.09 M | — | -44.79% | -67.43% | $2.19 | $0.47 |
| 462 | Palatin Technologies, Inc. | $8.62 | — | $15.07 M | — | 478.76% | -53.7% | $31 | $5 |
| 463 | Senti Biosciences Holdings, Inc. | $0.46 | — | $14.66 M | — | -171.08% | -503.79% | $2.88 | $0.42 |
| 464 | Lexaria Bioscience Corp. | $0.55 | — | $13.96 M | — | -443.04% | -160.72% | $1.55 | $0.46 |
| 465 | KALA BIO, Inc. | $0.73 | — | $13.85 M | — | -88.86% | -366.61% | $1,030 | $0.73 |
| 466 | BioCardia, Inc. | $0.92 | — | $13.8 M | — | -843.83% | -221.68% | $2.42 | $0.78 |
| 467 | Phio Pharmaceuticals Corp. | $1.13 | — | $13.13 M | — | -45.76% | -77.34% | $4.19 | $0.81 |
| 468 | Cocrystal Pharma, Inc. | $0.93 | — | $12.91 M | — | -120.22% | -150.61% | $2.67 | $0.86 |
| 469 | Lunai Bioworks Inc. | $2.76 | — | $12.9 M | — | 88.63% | -67% | $28 | $1.21 |
| 470 | Intensity Therapeutics, Inc. | $4.4 | — | $12.7 M | — | -100.14% | -136.82% | $43.5 | $3.51 |
| 471 | IN8bio, Inc. | $1.24 | — | $12.11 M | — | -68.2% | -96.39% | $2.73 | $1.17 |
| 472 | Moleculin Biotech, Inc. | $2.15 | — | $11.69 M | — | -164.37% | 17.93% | $21.5 | $1.79 |
| 473 | Psyence Biomedical Ltd. | $3.11 | 45.15 | $11.67 M | — | -54.49% | -6.35% | $468.38 | $1.92 |
| 474 | Kiora Pharmaceuticals, Inc. | $2.53 | — | $11.35 M | — | -45.87% | -51.37% | $3.23 | $1.76 |
| 475 | Exicure, Inc. | $1.93 | — | $10.93 M | — | -99.65% | -179.41% | $9.5 | $1.43 |
| 476 | Theriva Biologics, Inc. | $0.23 | — | $10.72 M | — | -85.21% | -178.29% | $0.86 | $0.16 |
| 477 | BioVie Inc. | $1.29 | — | $9.84 M | — | -93.67% | -101.09% | $9.09 | $1.06 |
| 478 | Aspire Biopharma Holdings, Inc. | $7.54 | — | $9.61 M | — | 308.11% | -83.31% | $1,050 | $3.31 |
| 479 | Vistagen Therapeutics, Inc. | $0.23 | — | $9.35 M | — | -78.03% | -133.02% | $5.14 | $0.2 |
| 480 | Traws Pharma, Inc. | $0.61 | 2.49 | $9.3 M | — | -185.49% | 265% | $3.27 | $0.6 |
| 481 | Curis, Inc. | $4.75 | — | $8.97 M | — | -558.61% | -53.31% | $39 | $3.61 |
| 482 | CytoMed Therapeutics Limited | $0.97 | — | $8.9 M | — | -33.09% | -58.15% | $3.68 | $0.68 |
| 483 | BioRestorative Therapies, Inc. | $0.32 | — | $8.36 M | — | -4386.1% | -423.84% | $1.89 | $0.16 |
| 484 | Jupiter Neurosciences, Inc. | $0.17 | — | $8.3 M | — | -73.72% | -352.06% | $1.85 | $0.16 |
| 485 | Bolt Biotherapeutics, Inc. | $4.02 | — | $8.26 M | — | -71.68% | -100.9% | $7.2 | $3.75 |
| 486 | MetaVia Inc. | $1.58 | — | $8.21 M | — | -250.37% | -172.92% | $19.03 | $0.97 |
| 487 | Aprea Therapeutics, Inc. | $0.65 | — | $8.05 M | — | -100.49% | -58.84% | $2.22 | $0.55 |
| 488 | TransCode Therapeutics, Inc. | $8.4 | — | $7.98 M | — | -334.68% | -53.11% | $20.99 | $3.82 |
| 489 | CNS Pharmaceuticals, Inc. | $5.39 | — | $7.88 M | — | -241.26% | -239.7% | $10.59 | $1.9 |
| 490 | Liminatus Pharma, Inc. | $0.12 | — | $7.66 M | — | 30.51% | — | $9.38 | $0.1 |
| 491 | Aptorum Group Limited | $9.54 | — | $7.63 M | — | -12.89% | -9.33% | $4.47 | $0.6 |
| 492 | AEON Biopharma, Inc. | $0.29 | — | $7.57 M | — | 252.78% | -1.74% | $1.45 | $0.26 |
| 493 | Imunon, Inc. | $1.67 | — | $6.98 M | — | -191.16% | -341.23% | $8.19 | $1.59 |
| 494 | AIM ImmunoTech Inc. | $0.25 | — | $6.93 M | — | 2638.91% | -142.26% | $19.74 | $0.21 |
| 495 | Kairos Pharma, Ltd. | $0.36 | — | $6.89 M | — | -87.87% | -92.26% | $2.11 | $0.28 |
| 496 | PharmaCyte Biotech, Inc. | $0.61 | — | $6.6 M | — | -8.38% | -7.66% | $1.51 | $0.61 |
| 497 | Acurx Pharmaceuticals, Inc. | $1.52 | — | $6.53 M | — | -153.59% | -153.93% | $9.96 | $1.33 |
| 498 | Cadrenal Therapeutics, Inc. | $2.17 | — | $6.48 M | — | -491.51% | -411.02% | $14.64 | $2.07 |
| 499 | Xenetic Biosciences, Inc. | $2.7 | — | $6.37 M | — | -38.33% | -39.28% | $13.93 | $1.9 |
| 500 | Evogene Ltd. | $0.53 | — | $6.33 M | — | -84.53% | -38.31% | $1.5 | $0.37 |
| 501 | Ernexa Therapeutics Inc. | $4.54 | — | $6.21 M | 0.32% | -342.48% | -169.4% | $71.5 | $3.18 |
| 502 | Processa Pharmaceuticals, Inc. | $2.24 | — | $6.2 M | — | -250.81% | -281.3% | $14.24 | $1.67 |
| 503 | Moolec Science SA | $8.45 | — | $6.19 M | — | 11.2% | -150.93% | $59.85 | $3.07 |
| 504 | BioAtla, Inc. | $3.69 | — | $6.14 M | — | 732.7% | -357.92% | $71.5 | $3.12 |
| 505 | Jaguar Health, Inc. | $1.26 | — | $6.14 M | — | -91.43% | -582.86% | $92.75 | $1.02 |
| 506 | Pulmatrix, Inc. | $1.7 | — | $6.14 M | — | -135.67% | -96.97% | $6.3 | $1.16 |
| 507 | Adial Pharmaceuticals, Inc. | $2.74 | — | $5.94 M | — | -147.82% | -162.83% | $440.66 | $1.31 |
| 508 | CollPlant Biotechnologies Ltd. | $0.32 | — | $5.91 M | — | -141.54% | -160.28% | $3.23 | $0.27 |
| 509 | Curanex Pharmaceuticals Inc | $0.2 | — | $5.72 M | — | -37.04% | -85.41% | $9.18 | $0.2 |
| 510 | Reviva Pharmaceuticals Holdings, Inc. | $0.44 | — | $5.64 M | — | -233.59% | -111.82% | $17.2 | $0.26 |
| 511 | Lakewood-Amedex Biotherapeutics, Inc. | $0.39 | — | $5.53 M | — | — | — | $9.82 | $0.37 |
| 512 | Aptevo Therapeutics Inc. | $4.42 | — | $5.51 M | — | -124.44% | -198.5% | $59.4 | $3.68 |
| 513 | Jyong Biotech Ltd. | $2.58 | — | $5.45 M | — | 35.69% | 8.55% | $67 | $1.43 |
| 514 | Soligenix, Inc. | $0.36 | — | $5.45 M | — | -213.96% | -246.04% | $6.23 | $0.28 |
| 515 | YD Bio Ltd | $2.27 | — | $5.37 M | — | -22.15% | -21.42% | $25 | $1.7 |
| 516 | HCW Biologics Inc. | $3.38 | — | $5.35 M | — | -4764.31% | 98.31% | $44.1 | $1.5 |
| 517 | Alaunos Therapeutics, Inc. | $2.09 | — | $5.32 M | — | -233.25% | -165.94% | $4.59 | $1.67 |
| 518 | Silo Pharma, Inc. | $4.71 | — | $5.26 M | — | -61.55% | -88.41% | $15.15 | $3.31 |
| 519 | GeoVax Labs, Inc. | $0.99 | — | $5.21 M | — | -498.05% | -709.51% | $23.1 | $0.82 |
| 520 | XORTX Therapeutics Inc. | $2.04 | — | $5.1 M | — | -156.2% | -150.08% | $9.85 | $2.42 |
| 521 | Cardio Diagnostics Holdings, Inc. | $1.67 | — | $5.06 M | — | -90.54% | -78.82% | $7.91 | $0.97 |
| 522 | Alzamend Neuro, Inc. | $1.32 | — | $5.02 M | — | -113.32% | -177.48% | $3.48 | $0.84 |
| 523 | Dermata Therapeutics, Inc. | $1.28 | — | $5.01 M | — | -124.91% | -127.91% | $7.5 | $1.1 |
| 524 | Bio Green Med Solution, Inc. | $0.89 | — | $4.93 M | 0.03% | 552.16% | -51.2% | $19.87 | $0.57 |
| 525 | PMGC Holdings Inc. | $1.05 | — | $4.86 M | — | -76.42% | -116.96% | $309.12 | $1 |
| 526 | Enveric Biosciences, Inc. | $1.32 | — | $4.82 M | — | -210.04% | -220.99% | $17.64 | $1.26 |
| 527 | FibroBiologics, Inc. | $0.77 | — | $4.69 M | — | -211.82% | -767.07% | $14.4 | $0.73 |
| 528 | Mustang Bio, Inc. | $0.62 | — | $4.66 M | — | -25.13% | -35.38% | $2.19 | $0.53 |
| 529 | Revelation Biosciences, Inc. | $1.15 | — | $4.53 M | — | -94.64% | -107.66% | $12.88 | $0.88 |
| 530 | Ensysce Biosciences, Inc. | $0.29 | — | $4.38 M | — | -355% | -374.96% | $2.75 | $0.23 |
| 531 | Virax Biolabs Group Limited | $3.88 | — | $4.09 M | — | -107.11% | -102.54% | $28.5 | $2.5 |
| 532 | 60 Degrees Pharmaceuticals, Inc. | $1.57 | — | $4.02 M | — | -220.2% | -200.06% | $8.62 | $1.22 |
| 533 | Creative Medical Technology Holdings, Inc. | $0.83 | — | $3.98 M | — | -81.64% | -88.5% | $6.25 | $0.79 |
| 534 | Genprex, Inc. | $8.01 | — | $3.97 M | — | -194.32% | -247.33% | $1,210 | $6.71 |
| 535 | Galmed Pharmaceuticals Ltd. | $0.52 | — | $3.95 M | — | -38.45% | -64.1% | $2.09 | $0.41 |
| 536 | Artelo Biosciences, Inc. | $1.12 | — | $3.9 M | — | 917.46% | -44.33% | $49.32 | $0.96 |
| 537 | Matinas BioPharma Holdings, Inc. | $0.28 | — | $3.85 M | — | -202.13% | -137.45% | $3.09 | $0.27 |
| 538 | Onconetix, Inc. | $0.89 | — | $3.29 M | — | -40.18% | -104.19% | $229.5 | $0.71 |
| 539 | Aditxt, Inc. | $0 | — | $3.1 M | — | -318.91% | -150.77% | $31,974.48 | $0 |
| 540 | Decoy Therapeutics Inc. | $4.92 | — | $2.74 M | — | -379.33% | -258.5% | $415.8 | $4.32 |
| 541 | SciSparc Ltd. | $4.75 | — | $2.69 M | — | -80.93% | -287.31% | $80.1 | $2.98 |
| 542 | GRI Bio, Inc. | $1.51 | — | $2.67 M | — | -198.85% | -199.52% | $80.36 | $1.42 |
| 543 | Silexion Therapeutics Corp | $2.51 | — | $2.67 M | — | -260.98% | -516.87% | $223.6 | $2.31 |
| 544 | Clearmind Medicine Inc. | $1.64 | — | $2.47 M | — | -475.2% | -143.79% | $524 | $1.63 |
| 545 | Oragenics, Inc. | $0.54 | — | $2.44 M | — | -113.05% | -59.11% | $1.49 | $0.5 |
| 546 | BiomX Inc. | $0.21 | — | $2.4 M | — | -101.67% | -190.95% | $13.7 | $0.19 |
| 547 | Azitra, Inc. | $0.14 | — | $2.36 M | — | -277.12% | -284.75% | $1.6 | $0.1 |
| 548 | Propanc Biopharma, Inc. | $1.38 | — | $2.18 M | — | -407.57% | -1743.6% | $188.99 | $1.3 |
| 549 | Bone Biologics Corporation | $1.11 | — | $1.99 M | — | -60.16% | -50.45% | $4.13 | $1.05 |
| 550 | CDT Equity Inc. | $3.83 | — | $1.98 M | — | 230.89% | -45.58% | $4,500 | $3 |
| 551 | Calidi Biotherapeutics, Inc. | $0.1 | — | $1.93 M | — | -410.2% | -438.03% | $10.92 | $0.11 |
| 552 | Valion Bio, Inc. | $0.52 | — | $1.66 M | — | — | -1.82% | $5.6 | $0.51 |
| 553 | VivoSim Labs, Inc. | $0.45 | 0.85 | $1.61 M | — | -115.61% | -15.56% | $5.3 | $0.44 |
| 554 | Cybin D/B/A Helus Pharma | $8.1 | — | $1.36 M | — | -60.35% | -74.33% | $12.7 | $5.3 |
| 555 | IO Biotech, Inc. | $0 | — | $0.22 M | — | -197.41% | -465.36% | $2.79 | $0 |