INDUSTRY
Biotechnology Industry Stocks
The Biotechnology industry covers 555 US-listed companies on StockSifting — NYSE and NASDAQ stocks operating within the Healthcare sector of the American equity market. Companies in the Biotechnology space compete on recurring themes including Treatment, Clinical, Phase, Disease, Therapeutics, which drive revenue growth, margin expansion, and long-term capital allocation decisions across the group. Representative names such as Vertex Pharmaceuticals Incorporated, Regeneron Pharmaceuticals, Inc., Moderna, Inc., and Revolution Medicines, Inc. show how businesses in this industry pursue differentiated strategies — through proprietary technology, distribution scale, pricing power, brand strength, or regulatory moats — to sustain returns above the cost of capital. For US investors, an industry-level screener is one of the most efficient ways to compare true peers: companies that face the same end-market demand, regulatory framework, raw material costs, and macroeconomic sensitivities, making valuation comparisons far more meaningful than cross-sector analysis. Key metrics to compare across Biotechnology industry stocks include P/E ratio for earnings valuation, ROCE for capital efficiency, ROE for equity profitability, Dividend Yield for income generation, Market Capitalisation for size and liquidity context, and the 52-week trading range for price momentum signals. Use the sortable table below to rank all 555 Biotechnology companies by any fundamental metric and identify which US-listed stocks in this industry offer the most attractive combination of quality, value, and income for your investment portfolio.
How to Analyse Biotechnology Industry Stocks
The Biotechnology industry page on StockSifting is built for US investors who want true peer comparison — businesses facing the same end-market dynamics, regulatory environment, and competitive pressures. Start by sorting the table by ROCE to identify the most capital-efficient operators in the group, then cross-reference with P/E to find high-quality companies available at reasonable valuations. Check Dividend Yield for income-oriented screening and the 52-week High/Low range for price momentum context. Click any company name to open its full profile — including quarterly financials, analyst data, and key ratios — to complete your due diligence before making any investment decision. All data is sourced from NYSE and NASDAQ filings and refreshed daily after US market close.
Key Metrics Explained for Biotechnology Industry Stocks
Every metric in the table below has a specific analytical purpose when comparing Biotechnology industry companies. Understanding what each ratio measures — and what a strong or weak reading looks like within this industry — is essential for making informed investment decisions.
- P/E Ratio (Price-to-Earnings)
- Measures how much investors pay for each dollar of trailing twelve-month earnings. A lower P/E relative to Biotechnology industry peers suggests a cheaper valuation; a higher P/E may reflect premium growth expectations or temporary earnings compression. Always compare P/E within the same industry — cross-sector P/E comparisons are misleading because capital intensity, growth rates, and margin profiles differ structurally.
- Market Capitalisation
- Total market value of a company's outstanding shares (price × shares outstanding). Within the Biotechnology industry, market cap indicates size, liquidity, and index eligibility. Large-cap companies (above $10B) typically offer more analyst coverage and tighter bid-ask spreads; small-caps may offer higher growth potential with commensurately higher risk and lower trading liquidity.
- ROCE — Return on Capital Employed
- Operating profit divided by total capital employed (equity + debt). ROCE is one of the most revealing profitability metrics for Biotechnology industry comparison: it shows which companies generate the most operating profit per dollar of total capital invested. ROCE consistently above 15% signals a strong competitive position; above 25% signals an exceptional business with durable advantages. Companies with high ROCE can self-fund growth and generate superior long-term shareholder returns without requiring continuous equity dilution or heavy borrowing.
- ROE — Return on Equity
- Net income divided by shareholders' equity. ROE measures how efficiently management generates profit from the equity shareholders have invested. In the Biotechnology industry, ROE above 15% is generally considered strong; below 8% raises questions about capital allocation efficiency. Note: high ROE driven by excessive leverage (high D/E ratio) is a warning sign rather than a quality indicator — always check debt levels alongside ROE.
- Dividend Yield
- Annual dividends per share as a percentage of the current share price. For income-oriented US investors, dividend yield is a key criterion — particularly in Biotechnology industry companies with stable, recurring cash flows. A yield significantly above the industry median may indicate an attractive income opportunity or, alternatively, a price decline that warrants further investigation into dividend sustainability. Always verify payout ratio and free cash flow coverage before relying on a high yield as an investment signal.
- 52-Week High / 52-Week Low
- The highest and lowest traded prices over the past 52 weeks. The 52-week range provides immediate context on price momentum and volatility within the Biotechnology industry: stocks trading near their 52-week high may reflect strong business momentum or elevated valuation; stocks near their 52-week low may represent contrarian opportunities or reflect deteriorating fundamentals. Always cross-reference with fundamental metrics rather than relying on price range alone.
Data Sources & Methodology
All financial data displayed on this Biotechnology industry page is sourced from NYSE and NASDAQ company filings, processed through StockSifting's daily data pipeline, and refreshed after each US market close. Fundamental metrics — earnings per share, book value, debt, and revenue — are updated as companies file quarterly reports (10-Q) and annual reports (10-K) with the SEC. Price data reflects the most recent closing price. StockSifting does not provide financial advice. All screening tools are for research and informational purposes only. Conduct your own due diligence before making any investment decision.
Biotechnology Industry Stocks — Frequently Asked Questions
Common questions US investors ask about the Biotechnology industry, answered with data from StockSifting's live screener.
What industry is Biotechnology on the US stock market?
Biotechnology is a recognised industry classification on the US equity market. StockSifting currently tracks 555 NYSE- and NASDAQ-listed companies in the Biotechnology industry, ranging from large-cap S&P 500 constituents to smaller-cap names. The Biotechnology industry page consolidates all these companies into a single sortable view, with live P/E ratio, market cap, ROCE, ROE, dividend yield, and 52-week price range data refreshed daily after US market close.
How many US stocks are in the Biotechnology industry?
StockSifting tracks 555 US-listed companies in the Biotechnology industry across NYSE and NASDAQ. Use the sortable table above to compare them by valuation, profitability, dividend yield, and trading range. Click any company name to open its full profile page with quarterly financials, key ratios, and historical data.
What metrics matter most for Biotechnology industry analysis?
For the Biotechnology industry, the most informative metrics to compare across peers are:
- ROCE — identifies companies with durable competitive advantages generating high returns on invested capital.
- P/E Ratio — measures relative valuation; low P/E within the industry may signal undervaluation.
- ROE — reveals how efficiently management deploys shareholder equity to generate profit.
- Dividend Yield — key for income-oriented US investors screening for reliable cash distributions.
- Market Cap — size and liquidity context; large-caps offer stability, small-caps offer growth potential.
- 52-Week Range — price momentum and volatility signal at a glance.
Comparing these metrics within the Biotechnology industry is more meaningful than cross-sector comparisons, because all companies face similar structural dynamics, cost bases, and regulatory environments.
How do I find the best Biotechnology industry stocks?
There is no single definition of "best" — it depends on your investment objective:
- Quality investors: Sort by ROCE descending to identify the most capital-efficient operators. Look for ROCE above 15% sustained over multiple years, combined with low D/E.
- Value investors: Sort by P/E ascending to find the cheapest earnings. Cross-reference with ROCE to avoid cheap junk — look for low P/E AND high ROCE simultaneously.
- Income investors: Sort by Dividend Yield descending. Verify sustainability by checking payout ratio and free cash flow in individual company profiles.
- Growth investors: Filter by market cap for smaller-cap names with high ROE, indicating efficient growth reinvestment.
Always click through to individual company pages for full due diligence. Nothing on this page constitutes financial advice. Past performance does not guarantee future results.
How often is the Biotechnology industry data updated?
StockSifting refreshes all Biotechnology industry data — price, P/E, market cap, ROCE, ROE, dividend yield, and 52-week range — daily after US market close. Fundamental data (earnings, book value, debt ratios) updates as companies file quarterly 10-Q and annual 10-K reports with the SEC. This means the screener reflects the most current publicly available information for every NYSE- and NASDAQ-listed company in the Biotechnology industry.
555 Companies in the Biotechnology Industry
Compare US-listed Biotechnology industry stocks by price, P/E ratio, market cap, dividend yield, ROCE, ROE, and 52-week high-low range. Click any column header to sort. Click any company name for the full profile.
| #↑ | Company↕ | Price↕ | P/E↕ | Mkt Cap↕ | Div Yield↕ | ROCE↕ | ROE↕ | 52W High↕ | 52W Low↕ |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals Incorporated | $451.63 | 26.79 | $114.63 B | — | — | 0.24% | $507.92 | $362.5 |
| 2 | Regeneron Pharmaceuticals, Inc. | $810.31 | 19.69 | $85.22 B | 0.44% | 10.23% | 13.81% | $859.34 | $541 |
| 3 | Moderna, Inc. | $140.33 | — | $58.11 B | — | -29.7% | -39.2% | $176.66 | $22.28 |
| 4 | Revolution Medicines, Inc. | $207.32 | — | $45.01 B | — | -57.28% | -54.06% | $224.31 | $39.17 |
| 5 | Royalty Pharma plc | $60.59 | 45.13 | $36.78 B | 2.96% | 8.21% | 12.25% | $64.38 | $34.08 |
| 6 | Alnylam Pharmaceuticals, Inc. | $260.1 | 44.07 | $35.61 B | — | 14.33% | 93.61% | $495.55 | $197.81 |
| 7 | Roivant Sciences Ltd. | $41.48 | — | $34.19 B | — | -21.06% | -6.12% | $37.97 | $12.54 |
| 8 | Insmed Incorporated | $124.89 | — | $27.58 B | — | -55.4% | -111.26% | $212.75 | $90.39 |
| 9 | Incyte Corporation | $124.4 | 15.93 | $25.69 B | — | 24.67% | 29.6% | $132.6 | $81.09 |
| 10 | Jazz Pharmaceuticals plc | $240.07 | 17.03 | $16.02 B | — | 5.5% | 21.37% | $266.38 | $123.88 |
| 11 | Ascendis Pharma A/S | $230.83 | 26.29 | $15.14 B | — | — | 3.33% | $250.74 | $160.86 |
| 12 | BridgeBio Pharma, Inc. | $74.76 | — | $14.63 B | — | -77.47% | -206.74% | $93.42 | $48.78 |
| 13 | Exelixis, Inc. | $57.67 | 16.99 | $14.62 B | — | 36.6% | 42.49% | $59.72 | $33.76 |
| 14 | Summit Therapeutics Inc. | $17.28 | — | $14.04 B | — | -161.37% | -168.93% | $29.23 | $12.07 |
| 15 | BioMarin Pharmaceutical Inc. | $64.63 | 176.49 | $12.88 B | — | 5.99% | 1.18% | $70.98 | $49.26 |
| 16 | Halozyme Therapeutics, Inc. | $108.31 | 30.24 | $12.51 B | — | 34.18% | 180.63% | $111.15 | $61.23 |
| 17 | Madrigal Pharmaceuticals, Inc. | $534.16 | — | $12.5 B | — | -31.61% | -56.65% | $615 | $393.61 |
| 18 | Arrowhead Pharmaceuticals, Inc. | $85.11 | 53.97 | $12.2 B | — | 8.27% | -60.54% | $95.49 | $27.1 |
| 19 | Corcept Therapeutics Incorporated | $113.98 | 218.66 | $12.07 B | — | 6.68% | 8.41% | $126.38 | $28.66 |
| 20 | Bio-Techne Corporation | $72.31 | 62.46 | $11.36 B | 0.5% | 10.19% | 8.9% | $72.62 | $43.2 |
| 21 | Axsome Therapeutics, Inc. | $207.82 | — | $10.83 B | — | -54.42% | -255.6% | $260.19 | $112.9 |
| 22 | Krystal Biotech, Inc. | $351.26 | 43.91 | $10.6 B | — | 13.1% | 19.34% | $382.54 | $136.73 |
| 23 | Apogee Therapeutics, Inc. | $135.07 | — | $10.22 B | — | -31.41% | -29.88% | $135.09 | $35.39 |
| 24 | Cytokinetics, Incorporated | $75.35 | — | $10.11 B | — | -50.1% | -131.19% | $88.31 | $47.22 |
| 25 | Praxis Precision Medicines, Inc. | $352.48 | — | $9.82 B | — | -37.15% | -43.02% | $392.7 | $37.19 |
| 26 | Nuvalent, Inc. | $0 | — | $9.79 B | — | -31.35% | -42.78% | $123.99 | $74.4 |
| 27 | Kymera Therapeutics, Inc. | $116.47 | — | $9.76 B | — | -20.82% | -21.5% | $130.05 | $42.22 |
| 28 | Ionis Pharmaceuticals, Inc. | $56.71 | — | $9.65 B | — | -13.92% | -110.92% | $86.74 | $50.01 |
| 29 | Protagonist Therapeutics, Inc. | $145.94 | 113.73 | $9.43 B | — | -25.39% | 12.03% | $160.81 | $54.5 |
| 30 | Vaxcyte, Inc. | $60.36 | — | $9.1 B | — | -33.02% | -37.57% | $65 | $30.81 |
| 31 | Crinetics Pharmaceuticals, Inc. | $84.95 | — | $9.01 B | — | -49.63% | -44.22% | $85.01 | $32.3 |
| 32 | TG Therapeutics, Inc. | $55.74 | 19.41 | $8.57 B | — | 13.56% | 72.3% | $59.3 | $26.76 |
| 33 | ImmunityBio, Inc. | $8.29 | — | $8.56 B | — | -58.17% | -193.29% | $12.43 | $1.95 |
| 34 | Immunovant, Inc. | $39.57 | — | $8.11 B | — | -61.93% | -69.59% | $45.42 | $14.58 |
| 35 | Spyre Therapeutics, Inc. | $90.79 | — | $7.85 B | — | -30.53% | -24.32% | $110.17 | $14.51 |
| 36 | Caris Life Sciences, Inc. | $24.82 | 67.39 | $7.08 B | — | 4.52% | 18.77% | $36.65 | $14.19 |
| 37 | Rhythm Pharmaceuticals, Inc. | $101.8 | — | $7.07 B | — | -51.31% | -80.48% | $122.2 | $74.5 |
| 38 | Scholar Rock Holding Corporation | $57.42 | — | $6.74 B | — | -110.26% | -159.12% | $61.76 | $27.07 |
| 39 | Arcellx Inc | $0 | — | $6.73 B | — | -50.64% | -55.46% | $115.13 | $60.35 |
| 40 | CG Oncology, Inc. | $73.4 | — | $6.62 B | — | -25.08% | -25.2% | $80.97 | $29.85 |
| 41 | Mirum Pharmaceuticals, Inc. | $99.53 | — | $6.55 B | — | -3.47% | -289.33% | $130 | $63.23 |
| 42 | Travere Therapeutics, Inc. | $66.07 | — | $6.15 B | — | -14.11% | -55.79% | $68.03 | $20.84 |
| 43 | Oruka Therapeutics, Inc. | $94.31 | — | $6.13 B | — | -25.79% | -20.76% | $115.52 | $14.67 |
| 44 | Terns Pharmaceuticals, Inc. | $0 | — | $6.12 B | — | -10.92% | -20.02% | $53.19 | $6.78 |
| 45 | Dianthus Therapeutics, Inc. | $109.13 | — | $6.05 B | — | -35.57% | -22.53% | $117.88 | $24.49 |
| 46 | Cogent Biosciences, Inc. | $35.28 | — | $6.03 B | — | -38.16% | -72.57% | $43.73 | $11.6 |
| 47 | Xenon Pharmaceuticals Inc. | $59.55 | — | $5.79 B | — | -63.09% | -43.98% | $72.66 | $35.6 |
| 48 | PTC Therapeutics, Inc. | $68.81 | 792.55 | $5.78 B | — | 44.37% | -351.91% | $90.87 | $56.51 |
| 49 | Ligand Pharmaceuticals Incorporated | $288.83 | 28.87 | $5.69 B | — | 3.1% | 20.06% | $326.63 | $161.82 |
| 50 | Erasca, Inc. | $16.28 | — | $5.66 B | — | -35.74% | -80.43% | $24.28 | $1.47 |
| 51 | CRISPR Therapeutics AG | $54.78 | — | $5.39 B | — | -31.41% | -24.39% | $78.48 | $44.12 |
| 52 | Apellis Pharmaceuticals, Inc. | $0 | 39.41 | $5.25 B | — | 7.37% | 39.71% | $41.14 | $16.83 |
| 53 | Definium Therapeutics, Inc. | $38.23 | — | $5.12 B | — | -44.54% | -85.23% | $49.7 | $8.77 |
| 54 | ACADIA Pharmaceuticals Inc. | $27.58 | 12.69 | $4.83 B | — | 8.14% | 32.39% | $30.96 | $19.69 |
| 55 | Celcuity Inc. | $93.02 | — | $4.68 B | — | -40.76% | -244.61% | $151.02 | $44.42 |
| 56 | Edgewise Therapeutics, Inc. | $43.82 | — | $4.68 B | — | -36.44% | -39.01% | $48.4 | $13.69 |
| 57 | Amicus Therapeutics Inc | $0 | — | $4.55 B | — | 4.84% | -12.02% | $14.5 | $7.61 |
| 58 | Dyne Therapeutics, Inc. | $20.31 | — | $4.53 B | — | -41.2% | -64.3% | $27.3 | $11.92 |
| 59 | Enliven Therapeutics, Inc. | $59.37 | — | $4.35 B | — | -26.04% | -18.55% | $62.32 | $14.79 |
| 60 | Relay Therapeutics, Inc. | $19.11 | — | $4.17 B | — | -50.82% | -42.27% | $21.27 | $3.85 |
| 61 | Veradermics, Incorporated | $103.83 | — | $4.12 B | — | -49.88% | -35.49% | $131.24 | $32 |
| 62 | Tarsus Pharmaceuticals, Inc. | $87.22 | — | $3.98 B | — | -16.64% | -13.53% | $91.53 | $48.2 |
| 63 | Iovance Biotherapeutics, Inc. | $8.7 | — | $3.98 B | — | -51.39% | -40.51% | $9.36 | $1.76 |
| 64 | Catalyst Pharmaceuticals, Inc. | $0 | 17.42 | $3.85 B | — | 26.94% | 23.65% | $32.56 | $19.05 |
| 65 | IDEAYA Biosciences, Inc. | $38.84 | — | $3.85 B | — | -15.17% | -16.47% | $42.68 | $23.23 |
| 66 | Tango Therapeutics, Inc. | $22.7 | — | $3.8 B | — | -29.52% | -25.74% | $34.39 | $6.25 |
| 67 | Arcus Biosciences, Inc. | $29.06 | — | $3.78 B | — | -42.51% | -89.54% | $31.73 | $11.04 |
| 68 | AbCellera Biologics Inc. | $11.44 | — | $3.7 B | — | -15.72% | -17.49% | $12.58 | $2.75 |
| 69 | uniQure N.V. | $45.68 | — | $3.59 B | — | -24.65% | -111.96% | $71.5 | $8.73 |
| 70 | Denali Therapeutics Inc. | $22.08 | — | $3.56 B | — | -53.07% | -55.27% | $27.3 | $12.58 |
| 71 | NewAmsterdam Pharma Company N.V. | $25.63 | — | $3.53 B | — | -33.02% | -38.33% | $42.2 | $23.05 |
| 72 | Viking Therapeutics, Inc. | $30.38 | — | $3.53 B | — | — | -0.7% | $43.15 | $22.96 |
| 73 | Celldex Therapeutics, Inc. | $39.12 | — | $3.12 B | — | -54.02% | -52.35% | $45.14 | $22.1 |
| 74 | Beam Therapeutics Inc. | $26.83 | — | $3.06 B | — | -27.72% | -7.7% | $38.26 | $18.72 |
| 75 | Disc Medicine, Inc. | $76.84 | — | $3.04 B | — | -30.64% | -37.17% | $99.5 | $40 |
| 76 | Immunome, Inc. | $26.81 | — | $3.04 B | — | -35.12% | -50.56% | $30.06 | $8.66 |
| 77 | Arcutis Biotherapeutics, Inc. | $24.39 | 105.33 | $3 B | — | -4.03% | 15.05% | $31.77 | $16.21 |
| 78 | MBX Biosciences, Inc. | $62.99 | — | $2.97 B | — | -26.53% | -26.01% | $72.64 | $9.63 |
| 79 | Pharvaris N.V. | $37.84 | — | $2.86 B | — | -54.28% | -61.01% | $38.13 | $20.65 |
| 80 | SELLAS Life Sciences Group, Inc. | $13.96 | — | $2.8 B | — | -39.64% | -35.91% | $15.88 | $1.39 |
| 81 | Soleno Therapeutics, Inc. | $0 | 28.77 | $2.76 B | — | 2.98% | 22.86% | $72.99 | $29.43 |
| 82 | AtaiBeckley Inc. | $7.28 | — | $2.74 B | — | -76% | -353.23% | $7.45 | $3.27 |
| 83 | Nurix Therapeutics, Inc. | $26.13 | — | $2.71 B | — | -47.48% | -76.09% | $28.23 | $8.2 |
| 84 | Viridian Therapeutics, Inc. | $23.17 | — | $2.6 B | — | -43.85% | -61.35% | $34.29 | $13.18 |
| 85 | Vera Therapeutics, Inc. | $35.28 | — | $2.59 B | — | -46.31% | -84.13% | $56.05 | $21.96 |
| 86 | Kailera Therapeutics, Inc. | $19.9 | — | $2.58 B | — | — | -0.37% | $28.23 | $18.5 |
| 87 | Precigen, Inc. | $6.87 | — | $2.54 B | — | -90.19% | -498.32% | $7.71 | $2.99 |
| 88 | Nektar Therapeutics | $75.44 | — | $2.53 B | — | -57.64% | -37.54% | $109 | $33.4 |
| 89 | Mineralys Therapeutics, Inc. | $31.12 | — | $2.49 B | — | -26.38% | -57.97% | $47.65 | $22.3 |
| 90 | Harmony Biosciences Holdings, Inc. | $42.07 | 13.57 | $2.46 B | — | 20.45% | 20.06% | $43.49 | $25.52 |
| 91 | Trevi Therapeutics, Inc. | $16.82 | — | $2.46 B | — | -26.85% | -23.59% | $20.22 | $6.93 |
| 92 | Nuvation Bio Inc. | $6.61 | — | $2.4 B | — | -41.57% | -49.73% | $9.75 | $2.99 |
| 93 | Sarepta Therapeutics, Inc. | $20.94 | 27.89 | $2.38 B | — | -29.18% | -9.96% | $25.32 | $14.68 |
| 94 | Biohaven Ltd. | $14.72 | — | $2.37 B | — | -222.16% | -639.95% | $18.57 | $7.48 |
| 95 | Ocular Therapeutix, Inc. | $11.37 | — | $2.34 B | — | -35.66% | -59.87% | $16.44 | $6.23 |
| 96 | Palvella Therapeutics, Inc. | $152.28 | — | $2.27 B | — | -80.06% | -47.84% | $161.38 | $52.36 |
| 97 | Zymeworks Inc. | $28.11 | — | $2.26 B | — | -30.42% | -72.07% | $31.34 | $14.06 |
| 98 | Day One Biopharmaceuticals Inc | $0 | — | $2.22 B | — | -28.56% | -23.43% | $21.53 | $6.67 |
| 99 | Kodiak Sciences Inc. | $35.07 | — | $2.22 B | — | -76.6% | -273.23% | $47.84 | $8.55 |
| 100 | Rapport Therapeutics, Inc. | $46.09 | — | $2.2 B | — | -25.36% | -29.02% | $52.93 | $14.21 |
| 101 | ADMA Biologics, Inc. | $9.54 | 12.75 | $2.15 B | — | 34.51% | 39.59% | $20.46 | $7.21 |
| 102 | Zenas BioPharma, Inc. | $33.05 | — | $2.14 B | — | -65.85% | -189.68% | $44.6 | $13.5 |
| 103 | Aurinia Pharmaceuticals Inc. | $16.07 | 6.81 | $2.14 B | — | 16.2% | 59% | $19.25 | $10.34 |
| 104 | UroGen Pharma Ltd. | $43.81 | — | $2.11 B | — | -81.06% | -204.47% | $50.81 | $15.86 |
| 105 | Generate Biomedicines, Inc. | $15.9 | — | $2.1 B | — | -94.79% | -103.72% | $22.67 | $11 |
| 106 | Vericel Corporation | $40.1 | 93.26 | $2.05 B | — | — | 0.07% | $43.57 | $28.95 |
| 107 | Xencor, Inc. | $25.33 | — | $1.98 B | — | -22.77% | -28.66% | $30.61 | $8.19 |
| 108 | Agios Pharmaceuticals, Inc. | $33.55 | — | $1.98 B | — | -38.86% | -35.67% | $46 | $22.24 |
| 109 | Recursion Pharmaceuticals, Inc. | $3.44 | — | $1.95 B | — | -48.86% | -50.41% | $7.18 | $2.77 |
| 110 | GH Research PLC | $27.79 | — | $1.94 B | — | -21.68% | -19.83% | $31.44 | $11.83 |
| 111 | Vir Biotechnology, Inc. | $11.18 | — | $1.93 B | — | -52.69% | -14.86% | $11.94 | $4.75 |
| 112 | Stoke Therapeutics, Inc. | $30.05 | — | $1.92 B | — | -5.71% | -59.36% | $40.22 | $19.55 |
| 113 | Maravai LifeSciences Holdings, Inc. | $7.19 | — | $1.9 B | — | -17.71% | -35.42% | $9.42 | $2.37 |
| 114 | Ascentage Pharma Group Internat | $17.44 | — | $1.89 B | — | -25.48% | -124.87% | $83.15 | $30 |
| 115 | Damora Therapeutics, Inc. | $29.17 | — | $1.86 B | — | -87.69% | -123.08% | $34.89 | $16.5 |
| 116 | Syndax Pharmaceuticals, Inc. | $19.94 | — | $1.84 B | — | -66.67% | -372.94% | $25.59 | $12.99 |
| 117 | Taysha Gene Therapies, Inc. | $5.48 | — | $1.82 B | — | -34.88% | -56.19% | $7.3 | $2.71 |
| 118 | Intellia Therapeutics, Inc. | $12.74 | — | $1.79 B | — | -59.74% | -57.79% | $28.25 | $7.95 |
| 119 | Inhibrx Biosciences, Inc. | $114.34 | — | $1.78 B | — | -119.83% | -269.56% | $155.29 | $26.19 |
| 120 | Septerna, Inc. | $37.37 | — | $1.72 B | — | -15.87% | -6.31% | $51.1 | $13.67 |
| 121 | Tyra Biosciences, Inc. | $26.73 | — | $1.71 B | — | -50.19% | -46.39% | $40.65 | $11.7 |
| 122 | Novavax, Inc. | $10.19 | 3.52 | $1.69 B | — | 76.84% | 283.08% | $11.97 | $6.2 |
| 123 | Fortrea Holdings Inc. | $17.06 | — | $1.68 B | — | -1.7% | -15.53% | $21.39 | $8.3 |
| 124 | AnaptysBio, Inc. | $56.6 | — | $1.68 B | — | 14.7% | -13.09% | $72.36 | $11.4 |
| 125 | Immatics N.V. | $9.44 | — | $1.66 B | — | -35.05% | -47.04% | $12.41 | $5.67 |
| 126 | Forte Biosciences, Inc. | $76.99 | — | $1.63 B | — | -113.91% | -94.82% | $77.2 | $10.11 |
| 127 | LB Pharmaceuticals Inc | $49.39 | — | $1.59 B | — | -9.95% | -25.91% | $50.16 | $13.36 |
| 128 | Innoviva, Inc. | $21.34 | 4.31 | $1.54 B | — | 10.33% | 30.03% | $25.15 | $16.52 |
| 129 | Bicara Therapeutics Inc. | $23.71 | — | $1.53 B | — | -38.7% | -41.49% | $30.99 | $10.29 |
| 130 | ArriVent BioPharma, Inc. | $30.28 | — | $1.53 B | — | -57.79% | -50.26% | $35.83 | $17 |
| 131 | Absci Corporation | $8.91 | — | $1.51 B | — | -64.8% | -59.21% | $12.05 | $2.24 |
| 132 | Ultragenyx Pharmaceutical Inc. | $14.88 | — | $1.51 B | — | -46.6% | -414.17% | $39.89 | $13.81 |
| 133 | Aktis Oncology, Inc. | $25.02 | — | $1.5 B | — | -31.96% | -30.8% | $34.19 | $14.72 |
| 134 | Vor Biopharma Inc. | $25.1 | 2.36 | $1.48 B | — | -84.67% | -142.13% | $49.95 | $6.5 |
| 135 | Alumis Inc. | $10.58 | — | $1.48 B | — | -134.01% | -102.97% | $31.35 | $3.76 |
| 136 | Maze Therapeutics, Inc. | $26.37 | — | $1.46 B | — | -38.15% | -34.94% | $53.65 | $14.27 |
| 137 | KalVista Pharmaceuticals, Inc. | $0 | — | $1.44 B | — | -89% | -237.53% | $27 | $10.41 |
| 138 | Cullinan Therapeutics, Inc. | $21.69 | — | $1.42 B | — | -58.85% | -52.89% | $23.19 | $5.68 |
| 139 | Replimune Group, Inc. | $14.77 | — | $1.42 B | — | -53.14% | -159.32% | $16.33 | $1.5 |
| 140 | Alto Neuroscience, Inc. | $35.81 | — | $1.4 B | — | -38.28% | -46.46% | $37.48 | $3.47 |
| 141 | Avalyn Pharma Inc. | $31.45 | — | $1.39 B | — | — | -0.68% | $32.23 | $24.15 |
| 142 | Omeros Corporation | $19.12 | 10.99 | $1.37 B | — | -49.6% | 107.5% | $19.65 | $3.94 |
| 143 | Hemab Therapeutics Holdings, Inc. | $29.24 | — | $1.37 B | — | — | -0.47% | $36.61 | $23 |
| 144 | Alpha Tau Medical Ltd. | $14.84 | — | $1.36 B | — | -44.45% | -73.23% | $15.17 | $3.43 |
| 145 | MeiraGTx Holdings plc | $13.53 | 16.89 | $1.33 B | — | -86.95% | 74.56% | $15.35 | $6.62 |
| 146 | ORIC Pharmaceuticals, Inc. | $12.62 | — | $1.33 B | — | -36.81% | -35.35% | $14.93 | $7.23 |
| 147 | MannKind Corporation | $4.16 | 144.86 | $1.31 B | — | 7.49% | -297.71% | $6.51 | $2.23 |
| 148 | MoonLake Immunotherapeutics | $14.94 | — | $1.28 B | — | -64.61% | -82.68% | $62.75 | $5.95 |
| 149 | Jade Biosciences, Inc. | $19.45 | — | $1.27 B | 0% | -34.07% | -49.11% | $28 | $6.91 |
| 150 | Janux Therapeutics, Inc. | $20.04 | — | $1.24 B | — | -16.15% | -10.79% | $35.34 | $12.12 |
| 151 | Corvus Pharmaceuticals, Inc. | $13.93 | — | $1.21 B | — | -69.6% | -36.15% | $26.95 | $5.64 |
| 152 | Silence Therapeutics plc | $13.69 | — | $1.21 B | — | -76.17% | -103.26% | $5.99 | $1.06 |
| 153 | Monte Rosa Therapeutics, Inc. | $14.27 | — | $1.18 B | — | -14.1% | -43.31% | $25.77 | $4.79 |
| 154 | Kura Oncology, Inc. | $12.52 | — | $1.18 B | — | -48.86% | -207.18% | $13.9 | $7.36 |
| 155 | Sana Biotechnology, Inc. | $3.45 | — | $1.15 B | — | -60.83% | -134.49% | $6.55 | $2.61 |
| 156 | Savara Inc. | $5.53 | — | $1.1 B | — | -52.68% | -87.19% | $7 | $3.34 |
| 157 | Solid Biosciences Inc. | $9.93 | — | $1.1 B | — | -90.02% | -72.28% | $11.45 | $3.79 |
| 158 | Avalo Therapeutics, Inc. | $19.71 | — | $1.03 B | — | -70.45% | -58.03% | $24.27 | $9.54 |
| 159 | Arbutus Biopharma Corporation | $5.18 | 6.67 | $1.02 B | — | -30.53% | 90.98% | $5.45 | $3.5 |
| 160 | Geron Corporation | $1.51 | — | $1.01 B | — | -11.23% | -29.32% | $2.01 | $1.04 |
| 161 | Lexicon Pharmaceuticals, Inc. | $2.23 | — | $996.7 M | — | -29.8% | -40.4% | $2.68 | $1.05 |
| 162 | Immix Biopharma, Inc. | $13.25 | — | $995.11 M | — | -31.62% | -38.44% | $15.1 | $1.94 |
| 163 | Candel Therapeutics, Inc. | $12.6 | — | $977.91 M | — | -41.46% | -89.38% | $14 | $4.35 |
| 164 | Seaport Therapeutics, Inc. | $18.17 | — | $972.65 M | — | — | -0.28% | $23 | $14.85 |
| 165 | SpyGlass Pharma, Inc. | $28.92 | — | $967.98 M | — | -38.64% | -56.78% | $32.44 | $17.06 |
| 166 | Wave Life Sciences Ltd. | $4.91 | — | $957.65 M | — | -39.63% | -49.87% | $21.73 | $4.64 |
| 167 | Design Therapeutics, Inc. | $15.23 | — | $947.49 M | — | -37.28% | -34.03% | $17.25 | $5.28 |
| 168 | Ardelyx, Inc. | $3.77 | — | $941.93 M | — | -9.92% | -36% | $8.4 | $3.68 |
| 169 | Olema Pharmaceuticals, Inc. | $10.98 | — | $940.6 M | — | -37.1% | -48.22% | $36.26 | $6.35 |
| 170 | Oculis Holding AG | $12.16 | — | $925.34 M | — | -41% | -42.65% | $34.48 | $10.52 |
| 171 | Annexon, Inc. | $4.67 | — | $923.25 M | — | -92.11% | -106.15% | $7.18 | $2.1 |
| 172 | Rigel Pharmaceuticals, Inc. | $47.37 | 2.82 | $909.15 M | — | 30.28% | 96.49% | $52.24 | $24.95 |
| 173 | Aclaris Therapeutics, Inc. | $6.06 | — | $908.22 M | — | -53.3% | -61.65% | $6.6 | $1.74 |
| 174 | Odyssey Therapeutics, Inc. | $19.07 | — | $899.61 M | — | — | -0.86% | $20.3 | $15.35 |
| 175 | Climb Bio, Inc. | $15.9 | — | $891.41 M | — | -42.23% | -31.79% | $18.33 | $1.54 |
| 176 | Theravance Biopharma, Inc. | $17.06 | 16.48 | $886.77 M | — | -0.81% | 19.4% | $21.03 | $13.08 |
| 177 | Achieve Life Sciences, Inc. | $7.84 | — | $873.64 M | — | -167.79% | -193.49% | $8.64 | $2.62 |
| 178 | AgomAb Therapeutics NV | $14.91 | — | $849.24 M | — | -24.35% | -47.78% | $17.82 | $8.75 |
| 179 | 4D Molecular Therapeutics, Inc. | $14.63 | — | $827.01 M | — | -30.52% | -41.33% | $16.93 | $6.47 |
| 180 | CytomX Therapeutics, Inc. | $3.65 | — | $808.41 M | — | -21.31% | -38.46% | $8.21 | $1.9 |
| 181 | Nuvectis Pharma, Inc. | $23.99 | — | $799.45 M | — | -149.75% | -169.47% | $29.27 | $5.55 |
| 182 | Aura Biosciences, Inc. | $7.36 | — | $784.01 M | — | -74.67% | -73.18% | $9.54 | $4.73 |
| 183 | Crescent Biopharma, Inc. | $20.46 | — | $775.57 M | — | -74.74% | -100.26% | $27.41 | $8.72 |
| 184 | Neurogene Inc. | $38.13 | — | $772.44 M | — | -37.96% | -25.27% | $43.66 | $15.93 |
| 185 | Phathom Pharmaceuticals, Inc. | $9.43 | — | $768.56 M | — | -125.87% | -232.78% | $18.31 | $8.21 |
| 186 | Zevra Therapeutics, Inc. | $12.68 | 12.85 | $748.46 M | — | -1.72% | 32.77% | $15.04 | $7.16 |
| 187 | Assembly Biosciences, Inc. | $35.28 | — | $745.2 M | — | -5.8% | -0.02% | $39.7 | $20.23 |
| 188 | Verastem, Inc. | $8.08 | — | $742.62 M | — | -97.68% | -165.4% | $11.25 | $3.43 |
| 189 | MapLight Therapeutics, Inc. | $13.95 | — | $727.72 M | — | -36.5% | -63.84% | $40.43 | $9.1 |
| 190 | Gyre Therapeutics, Inc. | $7.17 | 119.4 | $727.39 M | — | 7.77% | -15.84% | $9.42 | $5.44 |
| 191 | BridgeBio Oncology Therapeutics, Inc. | $8.86 | 148.58 | $719.96 M | — | -35.28% | -46.9% | $14.87 | $7 |
| 192 | XOMA Royalty Corporation | $0 | 21 | $710.16 M | 0.78% | 4.79% | 32.41% | $45.22 | $22.29 |
| 193 | Eupraxia Pharmaceuticals Inc. | $8.25 | — | $682.79 M | — | -47.73% | -45.53% | $12.86 | $7.15 |
| 194 | Shattuck Labs, Inc. | $6.5 | — | $681.47 M | — | -61.34% | -43.57% | $8.33 | $1.45 |
| 195 | Allogene Therapeutics, Inc. | $1.86 | — | $680.62 M | — | -53.97% | -35.31% | $4.46 | $1.04 |
| 196 | Sagimet Biosciences Inc. | $10.71 | — | $673.81 M | — | -51.08% | -31.96% | $11.24 | $4.5 |
| 197 | Prime Medicine, Inc. | $3.56 | — | $671.09 M | — | -68.25% | -188.27% | $6.94 | $2.67 |
| 198 | MiMedx Group, Inc. | $4.67 | 106.77 | $666.13 M | — | 22.95% | 2.61% | $7.97 | $3.03 |
| 199 | Altimmune, Inc. | $3.36 | — | $665.25 M | — | -35.67% | -31.41% | $6.44 | $2.56 |
| 200 | CorMedix Inc. | $8.18 | 3.51 | $657.07 M | — | 23.03% | 44.64% | $13.83 | $6.13 |
| 201 | OmniAb, Inc. | $4.24 | — | $629.54 M | — | -24.23% | -16.59% | $5.43 | $1.3 |
| 202 | Contineum Therapeutics, Inc. | $15.94 | — | $628.27 M | — | -25.5% | -24.73% | $17.79 | $8.6 |
| 203 | Arvinas, Inc. | $9.08 | 66.02 | $613.98 M | — | -20.59% | 1.91% | $14.51 | $6.97 |
| 204 | First Tracks Biotherapeutics, Inc. | $17.42 | — | $607.83 M | — | — | — | $26.8 | $14.72 |
| 205 | ProKidney Corp. | $1.99 | — | $607.67 M | — | -54.13% | -28.1% | $3.48 | $1.3 |
| 206 | Zura Bio Limited | $6.13 | — | $602.23 M | — | -74.11% | -54.45% | $7.44 | $1.88 |
| 207 | Tectonic Therapeutic, Inc. | $30.4 | — | $601.14 M | — | -33.43% | -32.33% | $39.53 | $14.39 |
| 208 | Bright Minds Biosciences Inc. | $60.66 | — | $595.2 M | — | — | -0.15% | $123.75 | $23.18 |
| 209 | REGENXBIO Inc. | $8.76 | — | $590.16 M | — | -48.13% | -220.07% | $16.19 | $5.46 |
| 210 | Cabaletta Bio, Inc. | $3.27 | — | $588.32 M | — | -149.87% | -128.27% | $4.23 | $1.56 |
| 211 | Eikon Therapeutics, Inc. | $10.71 | — | $588.23 M | — | -62.8% | -119.66% | $17.4 | $7.9 |
| 212 | ARS Pharmaceuticals, Inc. | $5.39 | — | $558.89 M | — | -62.2% | -256.67% | $13.15 | $4.91 |
| 213 | Artiva Biotherapeutics, Inc. | $10.88 | — | $547.08 M | — | -76.21% | -60.22% | $14.53 | $2.22 |
| 214 | Ovid Therapeutics Inc. | $2.75 | — | $546.83 M | — | -29.75% | -23.64% | $3.1 | $1.12 |
| 215 | Capricor Therapeutics, Inc. | $9.06 | — | $546.51 M | — | -33.78% | -56.6% | $40.37 | $2.96 |
| 216 | Entera Bio Ltd. | $3.01 | — | $521.5 M | — | -83.6% | -147.19% | $4.2 | $0.91 |
| 217 | Kyverna Therapeutics, Inc. | $8.07 | — | $510.21 M | — | -65.99% | -81.91% | $13.67 | $3.6 |
| 218 | Prothena Corporation plc | $9.54 | — | $504.13 M | — | -64.54% | -14.98% | $11.8 | $7.73 |
| 219 | Editas Medicine, Inc. | $3.03 | — | $496.06 M | — | -70.81% | -196.63% | $4.54 | $1.66 |
| 220 | Puma Biotechnology, Inc. | $9.39 | 20.22 | $492.97 M | — | 27.62% | 20.37% | $9.73 | $4.3 |
| 221 | Relmada Therapeutics, Inc. | $4.25 | — | $472.55 M | — | -67.49% | -47.52% | $8 | $1.3 |
| 222 | Ginkgo Bioworks Holdings, Inc. | $6.94 | — | $468.01 M | — | -29.68% | -60.21% | $17.58 | $5.37 |
| 223 | Atea Pharmaceuticals, Inc. | $5.68 | — | $467.59 M | — | -65.67% | -64.25% | $6.45 | $2.78 |
| 224 | Galectin Therapeutics Inc. | $4.14 | — | $464.92 M | — | -174.62% | -258.62% | $7.13 | $2.02 |
| 225 | C4 Therapeutics, Inc. | $3.55 | — | $462.57 M | — | -32.05% | -45.45% | $5.17 | $1.69 |
| 226 | Ocugen, Inc. | $1.33 | — | $461.19 M | — | -307.31% | -1306.71% | $2.73 | $1.01 |
| 227 | Monopar Therapeutics Inc. | $67.47 | — | $451.99 M | — | — | -0.16% | $105 | $29.18 |
| 228 | Arcturus Therapeutics Holdings Inc. | $15.63 | — | $449.65 M | — | -32.48% | -46.54% | $24.17 | $5.5 |
| 229 | Evommune, Inc. | $13.08 | — | $445.3 M | — | -39.16% | -46.76% | $33.2 | $10.47 |
| 230 | Rezolute, Inc. | $4.4 | — | $441.02 M | — | -48.84% | -58.82% | $11.46 | $1.07 |
| 231 | Prelude Therapeutics Incorporated | $5.3 | — | $435.73 M | — | -118.39% | -75.35% | $6.83 | $0.98 |
| 232 | Benitec Biopharma Inc. | $12.72 | — | $435.61 M | — | -42.71% | -45.91% | $16.76 | $9.85 |
| 233 | Fennec Pharmaceuticals Inc. | $12.45 | — | $434.48 M | — | -10.57% | -6.78% | $13.25 | $5.65 |
| 234 | Compass Therapeutics, Inc. | $2.21 | — | $428.61 M | — | -35.42% | -29.94% | $6.88 | $1.61 |
| 235 | Rocket Pharmaceuticals, Inc. | $3.71 | — | $423.73 M | — | -76.11% | -5.76% | $5.45 | $2.53 |
| 236 | Enanta Pharmaceuticals, Inc. | $13.5 | — | $410.09 M | — | -36.76% | -61.84% | $17.15 | $7.05 |
| 237 | Lexeo Therapeutics, Inc. | $4.76 | — | $401.21 M | — | -85.23% | -41.85% | $10.99 | $3.99 |
| 238 | X4 Pharmaceuticals, Inc. | $3.5 | — | $400.55 M | — | -32.82% | -63.05% | $4.83 | $2.8 |
| 239 | Larimar Therapeutics, Inc. | $4.08 | — | $397.87 M | — | -212.84% | -137.39% | $6.42 | $2.71 |
| 240 | EyePoint, Inc. | $4.56 | — | $394.85 M | — | -74.45% | -135.81% | $19.11 | $3.95 |
| 241 | Opus Genetics, Inc. | $4.34 | — | $388.52 M | — | -90.9% | -316.35% | $5.81 | $1.24 |
| 242 | Century Therapeutics, Inc. | $2.07 | — | $382.07 M | — | -5.16% | -52.76% | $3.04 | $0.43 |
| 243 | InflaRx N.V. | $2.17 | — | $380.42 M | — | -114.26% | -37.43% | $2.95 | $0.8 |
| 244 | Zentalis Pharmaceuticals, Inc. | $4.03 | — | $377.73 M | — | -57.45% | -52.77% | $6.95 | $1.21 |
| 245 | Agenus Inc. | $7.43 | 4.03 | $370.97 M | — | 21.26% | 76.63% | $8.85 | $2.71 |
| 246 | Palisade Bio, Inc. | $2.2 | — | $364.23 M | — | -13.92% | -33.47% | $2.85 | $0.53 |
| 247 | DiaMedica Therapeutics Inc. | $6.54 | — | $364 M | — | -61.16% | -77.68% | $10.42 | $5.25 |
| 248 | AC Immune SA | $2.78 | — | $359.35 M | — | -115.62% | -99.2% | $4 | $2.1 |
| 249 | Q32 Bio Inc. | $11.69 | 11.97 | $356.94 M | — | 33.52% | 137.41% | $23.57 | $1.63 |
| 250 | Conexeu Sciences Inc. | $13.28 | — | $355.35 M | — | — | — | $18.79 | $9.6 |
| 251 | Lyell Immunopharma, Inc. | $13.53 | — | $352.14 M | — | -69.37% | -91.62% | $45 | $11.47 |
| 252 | Inhibikase Therapeutics, Inc. | $2.43 | — | $348.84 M | — | -30.85% | -46.9% | $2.61 | $1.33 |
| 253 | Abeona Therapeutics Inc. | $5.85 | 5.5 | $343.1 M | — | -47.08% | -41.69% | $7.65 | $4 |
| 254 | Upstream Bio, Inc. | $6.19 | — | $339.58 M | — | -47.12% | -48.4% | $33.68 | $5.77 |
| 255 | SAB Biotherapeutics, Inc. | $3.63 | 25.5 | $338.47 M | — | -30.19% | 15.17% | $5.15 | $1.85 |
| 256 | Sutro Biopharma, Inc. | $19.1 | — | $332.78 M | — | -106.34% | -223.84% | $43.85 | $7.15 |
| 257 | ProQR Therapeutics N.V. | $2.05 | — | $332.37 M | — | -54.09% | -75.23% | $3.1 | $1.33 |
| 258 | Sionna Therapeutics, Inc. | $7.3 | — | $324.63 M | — | -28.32% | -32.94% | $54.97 | $4.01 |
| 259 | Pyxis Oncology, Inc. | $3.89 | — | $324.46 M | — | -119.93% | -101.77% | $5.55 | $1.03 |
| 260 | Vanda Pharmaceuticals Inc. | $5.33 | — | $318.42 M | — | -43.97% | -61.41% | $9.94 | $4.27 |
| 261 | Immuneering Corporation | $4.78 | — | $311.84 M | — | -26.76% | -27.15% | $10.08 | $3.86 |
| 262 | Orchestra BioMed Holdings, Inc. | $5.43 | — | $305.33 M | — | -52.8% | -125.78% | $5.78 | $2.2 |
| 263 | Fate Therapeutics, Inc. | $2.5 | — | $297.15 M | — | -52.22% | -65.08% | $3.23 | $0.93 |
| 264 | Fulcrum Therapeutics, Inc. | $3.82 | — | $293.74 M | — | -24% | -22.54% | $15.74 | $2.83 |
| 265 | Foghorn Therapeutics Inc. | $4.83 | — | $292.18 M | — | -59.34% | -301.61% | $7.61 | $3.27 |
| 266 | Turn Therapeutics Inc. | $12.66 | — | $291.92 M | — | -134.02% | -281.64% | $26.5 | $2.57 |
| 267 | Cartesian Therapeutics, Inc. | $8.95 | — | $280.47 M | — | -30.8% | -3215.82% | $11 | $5.6 |
| 268 | MacroGenics, Inc. | $4.32 | — | $280.28 M | — | -34.08% | -31.27% | $5.08 | $1.29 |
| 269 | ALX Oncology Holdings Inc. | $2 | — | $277.94 M | — | -292.37% | -90.3% | $2.66 | $1.01 |
| 270 | Entrada Therapeutics, Inc. | $7.52 | — | $277.62 M | — | -44.74% | -57.61% | $16.45 | $5.02 |
| 271 | CAMP4 THERAPEUTICS CORPORATION | $4.4 | — | $276.74 M | — | -50.89% | -194.74% | $7.75 | $1.46 |
| 272 | Alector, Inc. | $2.47 | — | $274.68 M | — | -69.73% | -295.17% | $3.4 | $1.09 |
| 273 | Lineage Cell Therapeutics, Inc. | $1.09 | — | $273.14 M | — | -21.52% | -71.14% | $2.09 | $1 |
| 274 | Surrozen, Inc. | $20.68 | — | $267.51 M | — | -47.4% | 58.23% | $35 | $11.25 |
| 275 | Satellos Bioscience Inc. | $9.18 | — | $265.84 M | — | -95.23% | -71.97% | $18.98 | $7.32 |
| 276 | Anavex Life Sciences Corp. | $2.85 | — | $265.11 M | — | -54.15% | -11.43% | $10.4 | $2.25 |
| 277 | Whitehawk Therapeutics, Inc. | $4.39 | — | $262.24 M | — | -83.93% | -53.89% | $5.5 | $1.76 |
| 278 | Niagen Bioscience, Inc. | $3.1 | 15.69 | $250.83 M | — | 16.53% | 20.5% | $10.52 | $2.87 |
| 279 | Neumora Therapeutics, Inc. | $1.25 | — | $246.14 M | — | -152.06% | -242.28% | $3.65 | $0.83 |
| 280 | Eledon Pharmaceuticals, Inc. | $2.93 | — | $245.41 M | — | -55.26% | -98.48% | $4.6 | $1.35 |
| 281 | Compugen Ltd. | $2.56 | 7.04 | $245.35 M | — | 23.38% | 47.72% | $3.23 | $1.29 |
| 282 | Invivyd, Inc. | $0.83 | — | $243.47 M | — | -22.89% | -59.73% | $3.07 | $0.53 |
| 283 | Atrium Therapeutics, Inc. | $11.35 | — | $242.73 M | — | -32.47% | -40.3% | $73.06 | $11.13 |
| 284 | NervGen Pharma Corp. | $2.19 | — | $238.93 M | — | -721.31% | -399.62% | $8.49 | $3.2 |
| 285 | Greenwich LifeSciences, Inc. | $15.9 | — | $234.12 M | — | -631.87% | -793.76% | $34.1 | $7.78 |
| 286 | Protara Therapeutics, Inc. | $3.89 | — | $232.84 M | — | -32.51% | -38.7% | $7.82 | $3.02 |
| 287 | Acumen Pharmaceuticals, Inc. | $3.16 | — | $229.97 M | — | -133.4% | -136.27% | $3.6 | $1.21 |
| 288 | Sol-Gel Technologies Ltd. | $69.37 | — | $227.61 M | — | -31.74% | -44.05% | $97.97 | $23.13 |
| 289 | Tonix Pharmaceuticals Holding Corp. | $13.16 | — | $225.36 M | — | -49.81% | -68.99% | $31.55 | $9.4 |
| 290 | Keros Therapeutics, Inc. | $11.17 | 2.55 | $224.44 M | — | 21.27% | -21.4% | $22.55 | $9.69 |
| 291 | AN2 Therapeutics, Inc. | $5.98 | — | $222.27 M | — | -71.59% | -53.52% | $7.19 | $1 |
| 292 | Coherus Oncology, Inc. | $1.37 | 1.05 | $219.39 M | — | -155.52% | -183.36% | $2.62 | $1.09 |
| 293 | Armata Pharmaceuticals, Inc. | $5.82 | — | $217.14 M | — | -45.96% | -120% | $16.34 | $2.76 |
| 294 | Voyager Therapeutics, Inc. | $3.4 | — | $216.28 M | — | -58.41% | -57.92% | $5.55 | $2.94 |
| 295 | PepGen Inc. | $3.21 | — | $215.4 M | — | -58.05% | -51.01% | $7.8 | $1.3 |
| 296 | Protalix BioTherapeutics, Inc. | $2.65 | 11.36 | $215.13 M | — | -9.85% | 31.61% | $3.19 | $1.52 |
| 297 | Corbus Pharmaceuticals Holdings, Inc. | $10.6 | — | $214.3 M | — | -57.84% | -87.05% | $20.56 | $7.12 |
| 298 | Minerva Neurosciences, Inc. | $4.37 | — | $211.52 M | — | -15.79% | -169.62% | $12.46 | $1.93 |
| 299 | Nkarta, Inc. | $3.23 | — | $209.14 M | — | -31.94% | -39.64% | $3.72 | $1.7 |
| 300 | Oramed Pharmaceuticals Inc. | $4.98 | 1.19 | $208.4 M | — | -7.12% | 72.96% | $5.47 | $2.09 |
| 301 | Alpha Cognition Inc. Common Stock | $9.52 | — | $207.33 M | — | -23.03% | -45.33% | $10.14 | $4.5 |
| 302 | Precision BioSciences, Inc. | $7.4 | — | $206.18 M | — | -35.84% | -91.6% | $9.62 | $3.53 |
| 303 | Cue Biopharma, Inc. | $30 | — | $199.34 M | — | -92.35% | -1032.19% | $45.5 | $4.97 |
| 304 | LENZ Therapeutics, Inc. | $5.33 | — | $187.27 M | — | -32.01% | -43.72% | $50.4 | $4.54 |
| 305 | Canton Strategic Holdings, Inc. | $2.23 | — | $181.67 M | — | -3.9% | -29.54% | $6.89 | $1.75 |
| 306 | Korro Bio, Inc. | $13.51 | — | $180.24 M | — | -85.99% | -114.26% | $55.89 | $5.2 |
| 307 | Immunic, Inc. | $12.74 | — | $178.88 M | — | 1572.16% | -95.67% | $17.43 | $5.06 |
| 308 | Tiziana Life Sciences Ltd | $0.99 | — | $177.34 M | — | -401.27% | -398.42% | $2.35 | $0.87 |
| 309 | ADC Therapeutics SA | $1.3 | — | $173.63 M | — | -42.38% | -229.23% | $4.98 | $0.78 |
| 310 | MediWound Ltd. | $13.44 | — | $171.58 M | — | -41.75% | -47.24% | $20.3 | $12.52 |
| 311 | Caribou Biosciences, Inc. | $1.54 | — | $168.32 M | — | -90.82% | -89.11% | $3.54 | $1.38 |
| 312 | Humacyte, Inc. | $0.59 | — | $168.04 M | — | -110.35% | -516.75% | $2.55 | $0.53 |
| 313 | Spruce Biosciences, Inc. | $59.09 | — | $166.49 M | — | -85.04% | -155.4% | $240 | $7.26 |
| 314 | Indaptus Therapeutics, Inc. | $1.85 | — | $162.56 M | — | -629.32% | -302.75% | $8.57 | $0.92 |
| 315 | Outlook Therapeutics, Inc. | $0.64 | — | $162.26 M | — | 246.27% | -415.51% | $2.54 | $0.16 |
| 316 | Codexis, Inc. | $1.43 | — | $159.88 M | — | -31.3% | -74.36% | $2.98 | $0.96 |
| 317 | Tenaya Therapeutics, Inc. | $0.66 | — | $153.19 M | — | -70.98% | -108.05% | $2.35 | $0.53 |
| 318 | Oncolytics Biotech Inc. | $0.81 | — | $151.38 M | — | -1939.57% | -440.39% | $4.49 | $1.48 |
| 319 | NRx Pharmaceuticals, Inc. | $3.47 | — | $151.1 M | — | 103.85% | -195.76% | $5.05 | $1.62 |
| 320 | Milestone Pharmaceuticals Inc. | $1.12 | — | $149.4 M | — | -62.4% | -288.36% | $3.06 | $1 |
| 321 | Inovio Pharmaceuticals, Inc. | $1.42 | — | $147.86 M | — | -283.35% | -190.5% | $2.98 | $0.56 |
| 322 | Biomea Fusion, Inc. | $1.93 | — | $147.14 M | — | -171.28% | -171.19% | $2.99 | $0.87 |
| 323 | OnKure Therapeutics, Inc. | $3.4 | — | $144.98 M | — | -112.02% | -49.02% | $5.38 | $2.23 |
| 324 | Unicycive Therapeutics, Inc. | $5.03 | — | $143.73 M | — | -97.75% | -88.81% | $8.74 | $3.71 |
| 325 | Equillium, Inc. | $2.41 | — | $140.13 M | — | -81.63% | -61.43% | $3.54 | $0.76 |
| 326 | TuHURA Biosciences, Inc. | $2.12 | — | $136.37 M | 0.01% | -120.19% | -154.27% | $3.43 | $0.41 |
| 327 | Vivani Medical, Inc. | $1.35 | — | $134.4 M | — | -84.04% | -191.05% | $1.92 | $0.92 |
| 328 | vTv Therapeutics Inc. | $32.79 | 55.59 | $131.87 M | — | -39.41% | -6.27% | $44 | $18 |
| 329 | NeOnc Technologies Holdings, Inc. | $4.07 | — | $130.46 M | — | 129% | 122.08% | $12.99 | $3 |
| 330 | Lixte Biotechnology Holdings, Inc. | $3.85 | — | $125.36 M | — | -431.9% | -124.69% | $8.38 | $2.36 |
| 331 | enGene Therapeutics Inc. | $1.92 | — | $121.92 M | — | -65% | -56.06% | $12.25 | $1.4 |
| 332 | Black Diamond Therapeutics, Inc. | $2.1 | 7.22 | $121.8 M | — | 15.61% | -38.8% | $4.94 | $1.6 |
| 333 | Cibus, Inc. | $1.61 | — | $121.52 M | — | -23.41% | -320.6% | $4.19 | $1.09 |
| 334 | Rani Therapeutics Holdings, Inc. | $0.87 | — | $120.62 M | — | -83.37% | -73.71% | $3.87 | $0.45 |
| 335 | Aardvark Therapeutics, Inc. | $5.33 | — | $117.74 M | — | -58.82% | -71.54% | $17.94 | $3.35 |
| 336 | Connect Biopharma Holdings Limited | $1.91 | — | $115.87 M | — | -24.19% | -165.41% | $3.82 | $1.23 |
| 337 | Nautilus Biotechnology, Inc. | $0.93 | — | $115.15 M | — | -36.49% | -37.58% | $4.31 | $0.65 |
| 338 | ProMIS Neurosciences, Inc. | $12.53 | — | $112.99 M | — | 3267.2% | -79.35% | $27.4 | $6.27 |
| 339 | Coya Therapeutics, Inc. | $4.61 | — | $111.66 M | — | -51.17% | -53.32% | $7.75 | $3.71 |
| 340 | OKYO Pharma Limited | $1.53 | — | $111.64 M | — | 127.79% | -51.58% | $3.2 | $1.34 |
| 341 | Fractyl Health, Inc. | $0.69 | — | $110.88 M | — | -93.93% | -852.14% | $2.44 | $0.38 |
| 342 | Genelux Corporation | $2.54 | — | $110.4 M | — | -259.44% | -205.85% | $8.54 | $2.29 |
| 343 | PolyPid Ltd. | $5.33 | — | $109.48 M | — | -226.3% | -311.07% | $5.73 | $3.06 |
| 344 | Seer, Inc. | $1.95 | — | $107.98 M | — | -27.82% | -27.23% | $2.41 | $1.55 |
| 345 | RenovoRx, Inc. | $2.2 | — | $107.86 M | — | -176.68% | -145.63% | $2.59 | $0.7 |
| 346 | Anixa Biosciences, Inc. | $2.9 | — | $104.45 M | — | -82.91% | -65.47% | $5.46 | $2.32 |
| 347 | Coeptis Therapeutics Holdings Inc | $2.95 | — | $102.06 M | — | -90.67% | -641.09% | $21.41 | $2.81 |
| 348 | Polaryx Therapeutics, Inc. | $2.02 | — | $99.69 M | — | -171.33% | -644.23% | $48.91 | $1.85 |
| 349 | Fortress Biotech, Inc. | $2.99 | 0.93 | $99.33 M | — | — | 1.1% | $4.53 | $1.7 |
| 350 | Atara Biotherapeutics, Inc. | $10.23 | 2.5 | $97.97 M | — | 674.99% | -315.42% | $19.14 | $3.92 |
| 351 | Cognition Therapeutics, Inc. | $1.01 | — | $97.95 M | — | -70.77% | -50.17% | $2.67 | $0.55 |
| 352 | VYNE Therapeutics Inc. | $29.3 | — | $93.5 M | — | -107.15% | -89.1% | $46.95 | $14.03 |
| 353 | Pelthos Therapeutics Inc. | $24.55 | — | $93.22 M | — | -31.06% | -78.04% | $37.5 | $18.19 |
| 354 | Acrivon Therapeutics, Inc. | $2.1 | — | $91.28 M | — | -73.75% | -70.14% | $3.56 | $1.27 |
| 355 | Verrica Pharmaceuticals Inc. | $5.26 | — | $91.05 M | — | -38.9% | -205.58% | $9.82 | $3.28 |
| 356 | ImmuCell Corporation | $9.84 | 114.19 | $89.91 M | — | 4.28% | 2.68% | $12.1 | $4.52 |
| 357 | Rallybio Corporation | $16.61 | 1.97 | $89.88 M | — | -56.97% | 68.56% | $17.57 | $3.67 |
| 358 | Adicet Bio, Inc. | $9.73 | — | $89.78 M | — | -71.49% | -74.9% | $17.44 | $6.01 |
| 359 | Aldeyra Therapeutics, Inc. | $1.54 | — | $89.28 M | — | -79.69% | -53.14% | $5.93 | $1.07 |
| 360 | OS Therapies Incorporated | $1.83 | — | $87.37 M | — | 582.87% | -567.59% | $2.35 | $1.15 |
| 361 | Gossamer Bio, Inc. | $0.18 | — | $85.69 M | — | -150.03% | -118.77% | $3.87 | $0.11 |
| 362 | Kalaris Therapeutics, Inc. | $3.63 | — | $85.18 M | — | -41.2% | -71.71% | $11.88 | $3.03 |
| 363 | Cardiff Oncology, Inc. | $1.1 | — | $84.8 M | — | -107.63% | -103.08% | $3.31 | $0.76 |
| 364 | MAIA Biotechnology, Inc. | $1.31 | — | $80.3 M | — | -618.06% | -211.15% | $3.19 | $0.87 |
| 365 | MediciNova, Inc. | $1.75 | — | $80.23 M | — | -31.77% | -26.51% | $1.96 | $1.17 |
| 366 | Telomir Pharmaceuticals, Inc. | $1.19 | — | $79.78 M | — | -178.22% | -102.69% | $2.09 | $0.89 |
| 367 | iBio, Inc. | $1.3 | — | $79.72 M | — | -108.92% | -53.86% | $3.82 | $0.77 |
| 368 | Gain Therapeutics, Inc. | $1.83 | — | $78.56 M | — | -96.12% | -161.58% | $4.34 | $1.53 |
| 369 | Rein Therapeutics Inc. | $0.86 | — | $76.7 M | — | -121.99% | -153.23% | $2.18 | $0.69 |
| 370 | NeurAxis, Inc. | $5.91 | — | $74.84 M | — | -216.78% | -169.07% | $9.33 | $2.21 |
| 371 | Annovis Bio, Inc. | $1.75 | — | $74.45 M | — | — | -2.21% | $5.5 | $1.54 |
| 372 | Cingulate Inc. | $5.19 | — | $74.16 M | — | -418.81% | -238.41% | $11.89 | $3.16 |
| 373 | Tenax Therapeutics, Inc. | $1.98 | — | $72.6 M | — | -58.09% | -61.55% | $19.4 | $1.31 |
| 374 | Nutriband Inc. | $6.1 | — | $72.57 M | — | -103.12% | -112.6% | $8.63 | $2.8 |
| 375 | Champions Oncology, Inc. | $5.05 | — | $72.52 M | — | 57.07% | -28.03% | $8.74 | $4.83 |
| 376 | Pliant Therapeutics, Inc. | $1.14 | — | $71.83 M | — | -74.87% | -69.56% | $1.95 | $1.02 |
| 377 | LeonaBio, Inc. | $8.02 | — | $71.23 M | — | -76.55% | -411.58% | $14.21 | $3.53 |
| 378 | Spero Therapeutics, Inc. | $1.19 | 9.54 | $70.46 M | — | 11.92% | 16.17% | $3.08 | $1.08 |
| 379 | Serina Therapeutics, Inc. | $2.5 | — | $69.34 M | — | -709.03% | -106.79% | $5.83 | $1.22 |
| 380 | PMV Pharmaceuticals, Inc. | $1.34 | — | $68.96 M | — | -81.99% | -78.11% | $1.88 | $1.02 |
| 381 | INmune Bio Inc. | $2.51 | — | $67.72 M | — | -128.97% | -82.87% | $2.5 | $1.09 |
| 382 | XBiotech Inc. | $2.18 | — | $67.07 M | — | -39.17% | -31.62% | $3.44 | $2.09 |
| 383 | Heron Therapeutics, Inc. | $0.35 | — | $65.29 M | — | -1.59% | -300.9% | $1.58 | $0.3 |
| 384 | Boundless Bio, Inc. | $2.86 | — | $65.29 M | — | -43.97% | -70.89% | $3.16 | $0.96 |
| 385 | Edesa Biotech, Inc. | $4.73 | — | $63.91 M | — | -57.24% | -124.21% | $20.32 | $0.72 |
| 386 | eXoZymes, Inc. | $6.31 | — | $63.58 M | — | -220.6% | -292.13% | $18.4 | $4.35 |
| 387 | Elicio Therapeutics, Inc. | $2.35 | — | $63.34 M | — | -210.11% | -582.97% | $16 | $2.36 |
| 388 | Apollomics, Inc. | $24.5 | — | $60.38 M | — | -737.55% | -693.39% | $42.12 | $3.95 |
| 389 | MiNK Therapeutics, Inc. | $11.45 | — | $59.4 M | — | 859.68% | -168.87% | $16.98 | $8.48 |
| 390 | Xilio Therapeutics, Inc. | $8.91 | — | $59.22 M | — | -42.66% | -9.23% | $12.74 | $6.47 |
| 391 | Impact BioMedical Inc. | $0.5 | 73.79 | $58.22 M | — | -26.29% | 19.45% | $0.83 | $0.37 |
| 392 | Seres Therapeutics, Inc. | $5.56 | 12.68 | $56.86 M | — | -79.05% | -60.32% | $29.98 | $4.32 |
| 393 | ImageneBio, Inc. | $5.05 | — | $55.05 M | — | -34.18% | -38.99% | $9.47 | $3.94 |
| 394 | Kezar Life Sciences, Inc. | $0 | — | $53.86 M | — | -74.59% | -64.42% | $7.55 | $3.53 |
| 395 | Dogwood Therapeutics, Inc. | $1.55 | 1.32 | $52.13 M | — | — | -0.35% | $9.5 | $1.28 |
| 396 | NovaBay Pharmaceuticals Inc | $0.87 | — | $51.92 M | 0% | -96.1% | -109.37% | $99.75 | $0.83 |
| 397 | Instil Bio, Inc. | $7.82 | — | $51.41 M | — | -26.15% | -26.78% | $33.83 | $5.67 |
| 398 | Hyperion DeFi, Inc. | $3.58 | 7.71 | $51.28 M | — | -38.69% | 9.77% | $15 | $2.34 |
| 399 | aTyr Pharma, Inc. | $0.48 | — | $48.78 M | — | -99.71% | -99.62% | $6.5 | $0.4 |
| 400 | Celularity Inc. | $1.54 | — | $48.63 M | — | -48.8% | -272.44% | $2.55 | $0.56 |
| 401 | Werewolf Therapeutics, Inc. | $0.98 | — | $46.96 M | — | -182.5% | -166.98% | $2.38 | $0.27 |
| 402 | Veru Inc. | $2.58 | — | $45.01 M | — | -161.13% | -45.89% | $7.33 | $2.05 |
| 403 | MindWalk Holdings Corp. | $1.35 | — | $44.94 M | — | -34.42% | -85.76% | $2.99 | $0.99 |
| 404 | Metagenomi Therapeutics, Inc. | $1.16 | — | $44.2 M | — | -48.45% | -51.23% | $3.95 | $1.13 |
| 405 | Grace Therapeutics, Inc. | $2.12 | — | $44.18 M | — | -23.81% | -33.73% | $5.18 | $1.79 |
| 406 | Karyopharm Therapeutics Inc. | $1.72 | — | $40.6 M | — | -554.58% | -182.43% | $10.99 | $1.72 |
| 407 | Tevogen Bio Holdings Inc. | $9.46 | — | $39.91 M | — | — | — | $71 | $4.13 |
| 408 | Filana Therapeutics, Inc. | $0.8 | — | $39.62 M | — | -128.99% | -58.78% | $2.27 | $0.8 |
| 409 | Lite Strategy, Inc. | $1.1 | — | $38.79 M | 0% | -103.09% | -68.86% | $4.45 | $0.69 |
| 410 | Aligos Therapeutics, Inc. | $5.76 | — | $38.78 M | — | -130.74% | -160.72% | $13.69 | $3.98 |
| 411 | CervoMed Inc. | $2.53 | — | $38.7 M | — | -155.27% | -156.02% | $10.74 | $2.13 |
| 412 | NextCure, Inc. | $8.42 | — | $35.79 M | — | -145.43% | -186.96% | $15.74 | $1.55 |
| 413 | Actuate Therapeutics, Inc. Common stock | $1.37 | — | $35.54 M | — | -270.08% | -346.18% | $8.8 | $0.9 |
| 414 | TransCode Therapeutics, Inc. | $1.89 | — | $34.88 M | — | -334.68% | -39.28% | $20.99 | $1.83 |
| 415 | Kyntra Bio, Inc. | $8.22 | 0.19 | $34.62 M | — | -50.18% | -290.91% | $12.58 | $6.32 |
| 416 | Context Therapeutics Inc. | $0.38 | — | $33.23 M | — | -65.65% | -82.06% | $3.62 | $0.35 |
| 417 | Quantum BioPharma Ltd. | $3.29 | — | $33.16 M | — | -300.19% | -625.19% | $28.59 | $2.85 |
| 418 | Actinium Pharmaceuticals, Inc. | $1.23 | 2.86 | $32.38 M | — | -82.74% | 83.42% | $1.74 | $0.74 |
| 419 | Quince Therapeutics, Inc. | $29.5 | — | $31.85 M | — | -33.74% | -127.02% | $910 | $15.1 |
| 420 | IGC Pharma, Inc. | $0.29 | — | $30.81 M | — | -114.73% | -113.58% | $0.45 | $0.23 |
| 421 | Hoth Therapeutics, Inc. | $0.7 | — | $30.69 M | — | -200.97% | -165.25% | $2.45 | $0.49 |
| 422 | Longeveron Inc. | $6.65 | — | $30.59 M | — | -377.18% | -223.19% | $12.3 | $4.75 |
| 423 | CEL-SCI Corporation | $1.65 | — | $28.67 M | — | -107.75% | -202.14% | $11.51 | $0.89 |
| 424 | NanoViricides, Inc. | $1.08 | — | $28.59 M | — | -127.59% | -92.69% | $2.23 | $0.85 |
| 425 | Estrella Immunopharma, Inc. | $0.64 | — | $28.11 M | — | 126.01% | -259.11% | $3.15 | $0.58 |
| 426 | Plus Therapeutics, Inc. | $2.7 | — | $26.64 M | — | -381.4% | -83.36% | $23.43 | $2.62 |
| 427 | TScan Therapeutics, Inc. | $0.34 | — | $26.54 M | — | -64.64% | -108.72% | $2.57 | $0.35 |
| 428 | Evaxion A/S | $3.17 | — | $25.69 M | — | -38.23% | -72.61% | $12.15 | $2.71 |
| 429 | ABVC BioPharma, Inc. | $1.06 | — | $25.59 M | — | -48% | -71.47% | $3.4 | $0.71 |
| 430 | Tvardi Therapeutics, Inc. | $1.94 | — | $25.48 M | — | -127.18% | -145.4% | $43.65 | $1.5 |
| 431 | BeyondSpring Inc. | $0.62 | — | $25.42 M | — | -72.39% | -133.13% | $2.44 | $0.57 |
| 432 | BriaCell Therapeutics Corp. | $2.9 | — | $25.23 M | — | — | -1.75% | $31.6 | $2.6 |
| 433 | Atossa Therapeutics, Inc. | $2.52 | — | $25.15 M | — | -94.38% | -102.99% | $19.35 | $1.7 |
| 434 | Lantern Pharma Inc. | $1.84 | — | $24.35 M | — | -275.14% | -198.35% | $4.7 | $1.11 |
| 435 | Jasper Therapeutics, Inc. | $0.71 | — | $23.58 M | — | -371.51% | -618.87% | $2.78 | $0.32 |
| 436 | Polyrizon Ltd. | $11.15 | — | $23.42 M | — | -27.56% | -17.84% | $18.2 | $2.88 |
| 437 | Lexaria Bioscience Corp. | $9.37 | — | $23.38 M | — | -443.04% | -160.72% | $23.25 | $4.21 |
| 438 | Neuphoria Therapeutics Inc. | $4.31 | — | $23.29 M | — | — | -0.63% | $21.4 | $3.65 |
| 439 | GridAI Technologies Corp. | $3.2 | — | $23.18 M | — | -27% | -56.79% | $6.93 | $1.87 |
| 440 | Palatin Technologies, Inc. | $12.68 | — | $22.6 M | — | 478.76% | -53.7% | $31 | $5.61 |
| 441 | Allarity Therapeutics, Inc. | $1.25 | — | $22.59 M | — | -148.49% | -152.77% | $2.06 | $0.77 |
| 442 | Cellectar Biosciences, Inc. | $2.41 | — | $22.4 M | — | -224.66% | -165.71% | $6.52 | $2.2 |
| 443 | Cocrystal Pharma, Inc. | $1.18 | — | $21.77 M | — | -120.22% | -207.47% | $2.67 | $0.76 |
| 444 | Dyadic International, Inc. | $0.52 | — | $20.84 M | — | -114.18% | -350.86% | $1.6 | $0.48 |
| 445 | Lipocine Inc. | $2.36 | — | $20.2 M | — | -71.64% | -64.75% | $12.37 | $1.81 |
| 446 | Cyclerion Therapeutics, Inc. | $3.36 | — | $19.9 M | — | -40.99% | -87.96% | $8.48 | $1.03 |
| 447 | Marker Therapeutics, Inc. | $1.28 | — | $19.67 M | — | -74.05% | -80.86% | $2.46 | $0.83 |
| 448 | Sensei Biotherapeutics, Inc. | $39.2 | — | $19.5 M | — | -119.5% | -283.67% | $41.16 | $7.45 |
| 449 | Pasithea Therapeutics Corp. | $0.6 | — | $19.38 M | — | -37.74% | -49.49% | $2.06 | $0.28 |
| 450 | NeuroSense Therapeutics Ltd. | $0.42 | — | $19.29 M | — | -383.35% | -395.28% | $1.98 | $0.25 |
| 451 | Enlivex Ltd. | $1.11 | 0.02 | $19.23 M | — | -0.65% | 248.08% | $27.15 | $1.02 |
| 452 | Adial Pharmaceuticals, Inc. | $6.65 | — | $18.7 M | — | -147.82% | -1693.21% | $249.81 | $1.31 |
| 453 | NewcelX Ltd. | $3.25 | — | $17.91 M | — | 23.66% | -163.83% | $24.6 | $1.83 |
| 454 | Psyence Biomedical Ltd. | $4.74 | 51.19 | $17.32 M | — | -54.49% | -53.38% | $216.37 | $1.92 |
| 455 | BioVie Inc. | $2.07 | — | $16.9 M | — | -93.67% | -126.02% | $3.79 | $0.82 |
| 456 | Pluri Inc. | $1.27 | — | $16.79 M | — | -348.95% | -53.15% | $5.29 | $1.25 |
| 457 | Tempest Therapeutics, Inc. | $0.99 | — | $16.46 M | — | -195.16% | -729.89% | $12.23 | $0.84 |
| 458 | BioCardia, Inc. | $1.11 | — | $16.35 M | — | -843.83% | -221.68% | $2.29 | $0.75 |
| 459 | Citius Pharmaceuticals, Inc. | $0.6 | — | $16.13 M | — | -44.79% | -67.15% | $2.19 | $0.47 |
| 460 | Vyome Holdings, Inc. | $2.09 | — | $15.58 M | — | -73.02% | -254.62% | $9.56 | $1.75 |
| 461 | Passage Bio, Inc. | $4.85 | — | $14.96 M | — | -110.08% | -218.59% | $20 | $3.29 |
| 462 | Lisata Therapeutics, Inc. | $1.86 | — | $14.87 M | — | -124.1% | -75.1% | $5.07 | $0.99 |
| 463 | CalciMedica, Inc. | $2.02 | — | $14.82 M | — | -235.71% | -138.8% | $36 | $2 |
| 464 | Daré Bioscience, Inc. | $0.71 | — | $14.18 M | — | -154.2% | -373.17% | $3.78 | $0.69 |
| 465 | Moleculin Biotech, Inc. | $0.75 | — | $13.83 M | — | -164.37% | -35.39% | $15.75 | $0.16 |
| 466 | Intensity Therapeutics, Inc. | $4.09 | — | $13.39 M | — | -100.14% | -116.61% | $43.5 | $3.51 |
| 467 | SeaStar Medical Holding Corporation | $2.95 | — | $13.13 M | — | -116.89% | -162.75% | $12.5 | $2.07 |
| 468 | Phio Pharmaceuticals Corp. | $1.03 | — | $12.55 M | — | -45.76% | -87.41% | $4.19 | $0.81 |
| 469 | Aspire Biopharma Holdings, Inc. | $8.85 | — | $12.44 M | — | 308.11% | -57.48% | $660 | $3.31 |
| 470 | PDS Biotechnology Corporation | $0.3 | — | $12.31 M | — | -150.13% | -346.03% | $1.55 | $0.2 |
| 471 | FibroBiologics, Inc. | $1.71 | — | $12.05 M | — | -211.82% | -536.78% | $12.4 | $0.62 |
| 472 | AEON Biopharma, Inc. | $0.23 | — | $12.01 M | — | 252.78% | -1.74% | $1.45 | $0.18 |
| 473 | IN8bio, Inc. | $1.14 | — | $11.83 M | — | -68.2% | -91.18% | $2.73 | $0.88 |
| 474 | Theriva Biologics, Inc. | $0.25 | — | $11.61 M | — | -85.21% | -93.49% | $0.86 | $0.16 |
| 475 | MetaVia Inc. | $1.7 | — | $11.53 M | — | -250.37% | -209.67% | $19.03 | $0.97 |
| 476 | Kiora Pharmaceuticals, Inc. | $2.51 | — | $11.28 M | — | -45.87% | -63.39% | $2.95 | $1.76 |
| 477 | Xenetic Biosciences, Inc. | $4.28 | — | $10.94 M | — | -38.33% | -40.62% | $13.93 | $1.9 |
| 478 | Azitra, Inc. | $0.17 | — | $10.88 M | — | -277.12% | -284.75% | $1.09 | $0.1 |
| 479 | GT Biopharma, Inc. | $5.24 | — | $10.87 M | — | -214.65% | -443.08% | $1.37 | $0.22 |
| 480 | Lunai Bioworks Inc. | $2.6 | — | $10.84 M | — | 88.63% | -67% | $17.84 | $1.21 |
| 481 | Vistagen Therapeutics, Inc. | $0.24 | — | $10.77 M | — | -78.03% | -152.59% | $5.14 | $0.2 |
| 482 | Senti Biosciences Holdings, Inc. | $0.32 | — | $10.36 M | — | -171.08% | -503.79% | $2.88 | $0.33 |
| 483 | Aprea Therapeutics, Inc. | $0.83 | — | $10 M | — | -100.49% | -46.3% | $1.69 | $0.55 |
| 484 | KALA BIO, Inc. | $0.54 | — | $9.81 M | — | -88.86% | -28.16% | $1,030 | $0.5 |
| 485 | Ensysce Biosciences, Inc. | $0.47 | — | $8.87 M | — | -355% | -374.96% | $2.75 | $0.23 |
| 486 | Imunon, Inc. | $1.54 | — | $8.87 M | — | -191.16% | -314.9% | $6.03 | $1.47 |
| 487 | Evogene Ltd. | $0.51 | — | $8.5 M | — | -84.53% | -38.31% | $1.5 | $0.37 |
| 488 | Traws Pharma, Inc. | $0.55 | 2.49 | $8.45 M | — | -185.49% | -225.02% | $3.27 | $0.43 |
| 489 | CNS Pharmaceuticals, Inc. | $5.94 | — | $8.37 M | — | -241.26% | -204.25% | $10.59 | $1.9 |
| 490 | Soligenix, Inc. | $0.38 | — | $8.27 M | — | -213.96% | -181.02% | $3.07 | $0.28 |
| 491 | Skye Bioscience, Inc. | $1.88 | — | $8.24 M | — | -289.25% | -217.27% | $39.92 | $1.64 |
| 492 | Exicure, Inc. | $1.41 | — | $8.18 M | — | -99.65% | -237.91% | $9.48 | $1.05 |
| 493 | CytoMed Therapeutics Limited | $0.87 | — | $8.09 M | — | -33.09% | -58.15% | $3.68 | $0.68 |
| 494 | Alzamend Neuro, Inc. | $1.68 | — | $8.01 M | — | -113.32% | -277.71% | $2.68 | $0.84 |
| 495 | YD Bio Ltd | $4.25 | — | $7.96 M | — | -22.15% | -21.42% | $25 | $1.7 |
| 496 | Curanex Pharmaceuticals Inc | $5.04 | — | $7.92 M | — | -37.04% | -109.11% | $183.6 | $3.58 |
| 497 | OSR Holdings, Inc. | $0.2 | — | $7.9 M | — | 79.82% | -11.67% | $0.91 | $0.07 |
| 498 | Bolt Biotherapeutics, Inc. | $3.86 | — | $7.51 M | — | -71.68% | -126.23% | $7.2 | $3.13 |
| 499 | Acurx Pharmaceuticals, Inc. | $1.43 | — | $7.48 M | — | -153.59% | -124.74% | $8.34 | $1.31 |
| 500 | Creative Medical Technology Holdings, Inc. | $1.08 | — | $7.32 M | — | -81.64% | -86.7% | $6.25 | $0.62 |
| 501 | Aditxt, Inc. | $0.01 | — | $7.29 M | — | -318.91% | -150.77% | $27,092.88 | $0 |
| 502 | Ernexa Therapeutics Inc. | $4.19 | — | $7.04 M | 0.28% | -342.48% | -169.4% | $71.5 | $3.18 |
| 503 | Reviva Pharmaceuticals Holdings, Inc. | $0.54 | — | $6.95 M | — | -233.59% | -111.82% | $17.2 | $0.26 |
| 504 | AIM ImmunoTech Inc. | $0.23 | — | $6.93 M | — | 2638.91% | -138.03% | $2.89 | $0.19 |
| 505 | CollPlant Biotechnologies Ltd. | $3.58 | — | $6.71 M | — | -141.54% | -160.28% | $31.8 | $2.64 |
| 506 | GRI Bio, Inc. | $2 | — | $6.3 M | — | -198.85% | -134.03% | $80.36 | $1.36 |
| 507 | Kairos Pharma, Ltd. | $1.77 | — | $6.23 M | — | -87.87% | -98.77% | $14.77 | $1.51 |
| 508 | Enveric Biosciences, Inc. | $1.42 | — | $6.22 M | — | -210.04% | -168.05% | $13.25 | $1.17 |
| 509 | Bio Green Med Solution, Inc. | $0.87 | — | $5.98 M | 0.03% | 552.16% | -31.6% | $7.49 | $0.57 |
| 510 | Processa Pharmaceuticals, Inc. | $2.16 | — | $5.75 M | — | -250.81% | -281.3% | $14.24 | $1.67 |
| 511 | Aptorum Group Limited | $6.28 | — | $5.7 M | — | -12.89% | -9.33% | $25.9 | $6 |
| 512 | Jyong Biotech Ltd. | $2.12 | — | $5.63 M | — | 35.69% | 8.55% | $67 | $1.43 |
| 513 | XORTX Therapeutics Inc. | $2.28 | — | $5.61 M | — | -156.2% | -150.08% | $9.85 | $2.42 |
| 514 | Lakewood-Amedex Biotherapeutics, Inc. | $0.39 | — | $5.53 M | — | — | — | $9.82 | $0.37 |
| 515 | Cardio Diagnostics Holdings, Inc. | $1.96 | — | $5.5 M | — | -90.54% | -82.27% | $7.91 | $0.97 |
| 516 | HCW Biologics Inc. | $2.51 | — | $5.4 M | — | -4764.31% | -19.32% | $36.65 | $1.5 |
| 517 | PharmaCyte Biotech, Inc. | $0.49 | — | $5.22 M | — | -8.38% | -50.28% | $1.51 | $0.47 |
| 518 | Pulmatrix, Inc. | $1.4 | — | $5.08 M | — | -135.67% | -96.97% | $5.5 | $1.16 |
| 519 | Moolec Science SA | $6.93 | — | $5.03 M | — | 11.2% | -150.93% | $23.22 | $3.07 |
| 520 | Liminatus Pharma, Inc. | $3.62 | — | $4.98 M | — | 30.51% | — | $145 | $3.42 |
| 521 | Dermata Therapeutics, Inc. | $1.25 | — | $4.87 M | — | -124.91% | -166.67% | $6.22 | $0.95 |
| 522 | VivoSim Labs, Inc. | $0.28 | 0.85 | $4.61 M | — | -115.61% | -15.56% | $5.3 | $0.26 |
| 523 | Cadrenal Therapeutics, Inc. | $1.2 | — | $4.35 M | — | -491.51% | -406.38% | $14.64 | $1.2 |
| 524 | PMGC Holdings Inc. | $4.85 | — | $4.22 M | — | -76.42% | -118.11% | $2,671.2 | $4.97 |
| 525 | Alaunos Therapeutics, Inc. | $1.57 | — | $4.14 M | — | -233.25% | -232.6% | $4.59 | $1.55 |
| 526 | Mustang Bio, Inc. | $0.54 | — | $4.11 M | — | -25.13% | -34.23% | $1.85 | $0.53 |
| 527 | Galmed Pharmaceuticals Ltd. | $3.83 | — | $4.04 M | — | -38.45% | -64.1% | $13.2 | $3.29 |
| 528 | Onconetix, Inc. | $0.84 | — | $4.03 M | — | -40.18% | -91.94% | $209.5 | $0.59 |
| 529 | Revelation Biosciences, Inc. | $1.01 | — | $4.02 M | — | -94.64% | -100.2% | $11.6 | $0.88 |
| 530 | Jupiter Neurosciences, Inc. | $3.08 | — | $4 M | — | -73.72% | -352.06% | $138 | $2.88 |
| 531 | BiomX Inc. | $0.15 | — | $3.95 M | — | -101.67% | -121.19% | $12.29 | $0.12 |
| 532 | Silo Pharma, Inc. | $2.28 | — | $3.81 M | — | -61.55% | -81.74% | $15.15 | $2.21 |
| 533 | BioRestorative Therapies, Inc. | $2.8 | — | $3.77 M | — | -4386.1% | -423.84% | $1.73 | $0.14 |
| 534 | Calidi Biotherapeutics, Inc. | $1.35 | — | $3.58 M | — | -410.2% | -438.03% | $27.84 | $1.25 |
| 535 | GeoVax Labs, Inc. | $0.47 | — | $3.56 M | — | -498.05% | -743.66% | $19 | $0.48 |
| 536 | Artelo Biosciences, Inc. | $6.19 | — | $3.31 M | — | 917.46% | -92.3% | $179.19 | $4.68 |
| 537 | 60 Degrees Pharmaceuticals, Inc. | $0.98 | — | $3.23 M | — | -220.2% | -211.48% | $8.62 | $0.9 |
| 538 | Aptevo Therapeutics Inc. | $1.88 | — | $3.15 M | — | -124.44% | -201.49% | $48.78 | $1.37 |
| 539 | Jaguar Health, Inc. | $0.41 | — | $3.08 M | — | -91.43% | -362.42% | $85.4 | $0.57 |
| 540 | SciSparc Ltd. | $5.1 | — | $3.03 M | — | -80.93% | -287.31% | $80.1 | $2.98 |
| 541 | Genprex, Inc. | $3.54 | — | $2.87 M | — | -194.32% | -163.13% | $1,210 | $3.37 |
| 542 | Virax Biolabs Group Limited | $2.63 | — | $2.83 M | — | -107.11% | -77.95% | $21.75 | $2.5 |
| 543 | Curis, Inc. | $1.27 | — | $2.82 M | — | -558.61% | -176.14% | $39 | $1.3 |
| 544 | Matinas BioPharma Holdings, Inc. | $0.18 | — | $2.67 M | — | -202.13% | -137.45% | $2.14 | $0.17 |
| 545 | Propanc Biopharma, Inc. | $1.03 | — | $2.55 M | — | -407.57% | -1743.6% | $46.76 | $0.95 |
| 546 | Oragenics, Inc. | $0.52 | — | $2.3 M | — | -113.05% | -59.11% | $1.45 | $0.48 |
| 547 | BioAtla, Inc. | $1.26 | — | $2.2 M | — | 732.7% | -357.92% | $71.5 | $1.07 |
| 548 | Silexion Therapeutics Corp | $0.34 | — | $2.02 M | — | -260.98% | -563.11% | $77.7 | $0.35 |
| 549 | Decoy Therapeutics Inc. | $2.63 | — | $1.76 M | — | -379.33% | -315.23% | $70.8 | $2.69 |
| 550 | Clearmind Medicine Inc. | $1.03 | — | $1.72 M | — | -475.2% | -143.79% | $524 | $1.16 |
| 551 | Valion Bio, Inc. | $0.52 | — | $1.66 M | — | — | -1.82% | $5.6 | $0.51 |
| 552 | Bone Biologics Corporation | $0.56 | — | $1.57 M | — | -60.16% | -57.85% | $2.89 | $0.54 |
| 553 | Cybin D/B/A Helus Pharma | $12.39 | — | $1.39 M | — | -60.35% | -74.33% | $19.86 | $5.3 |
| 554 | CDT Equity Inc. | $0.62 | — | $0.49 M | — | 230.89% | -22.3% | $2,440 | $0.61 |
| 555 | IO Biotech, Inc. | $0 | — | $0.22 M | — | -197.41% | -465.36% | $2.08 | $0 |